Poonam Thakur
@poonam_thakur6
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#firstgen Assistant Prof @tvmiiser. Interested in the neuroscience of Parkinson's disease. Previously @OfficialPU, @lunduniversity, @goetheuni
Thiruvananthapuram, India
Joined February 2014
RT @SutirthDey: Announcing the 9th Edition of the online "Biostatistics: A User's Perspective" course. This will be an intuitive understan….
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Grateful to @CureParkinsonsT UK for this feature on #ResearchAppreciationDay & their continued support for our preclinical research program for #Parkinsons. Their commitment to advancing fundamental research that can inform future therapeutic strategies for PD is commendable.🙏.
This #ResearchAppreciationDay, we’re launching our Meet the Researcher series! .In this interview, Assistant Professor Dr Poonam Thakur discusses studying repurposed drugs for Cure Parkinson’s, and why it's vital for scientists to engage with the public:
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RT @Ankita_JenaIITK: All these things were not enough for Air India. After torturous treatment from Air India, I somehow landed in JFK. Sur….
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RT @fchollet: Key to research success: ambition in vision, but pragmatism in execution. You must be guided by a long-term, ambitious goal t….
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Recently hit 10K followers! Grateful for the connection & support over the years. But can’t ignore how Indian #AcademicTwitter is slowly fading - fewer people, less engagement, more silence. Where are the vibrant discussions, the dissent, camaraderies? Let’s revive it 🙏.
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Time for our next set of students to fly from the nest. We tried to do new things with computational biology, data sciences and ML, faced some setbacks but also grew & learnt together. Best wishes to all of them for a bright future. Onwards & upwards 🙌
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RT @Saran240478: Biogroup India, a dynamic network of life science researchers, holds its seventh annual meeting at….
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Very proud of all the present and past lab members who have contributed to the study with immense hard work and patience: @Akshaya_cgr, Anish & Shaliya. Very thankful to @group_vv for help with NMR studies & funding agencies for the support.
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Our data show that glycated α-Synuclein may be a causal link, not just a correlation. A strong case for studying metabolic risk factors in neurodegenerative diseases.
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However, glycated α-Syn induced more intense neuroinflammation and earlier behavioural deficits. Thus, glycation changes how α-synuclein drives disease, making symptoms appear earlier. This could explain why people with diabetes are at increased risk of developing Parkinson's.
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Using several biophysical techniques, we demonstrate that glycation prevents α-synuclein from forming a cross-β-sheet structure; however, glycated assemblies still cause neurodegeneration in the mouse brain to the same extent as the beta-sheet-rich α-synuclein fibrils.
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Excited to share our new preprint! α-Synuclein misfolding is a key event in #Parkinson disease. But what happens when it gets glycated—a non-enzymatic change promoted by high sugar levels in #diabetes or hyperglycemia? .
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Yes! A significant step in improvement of RnD ecosystem. Looking forward to timely disbursal of funds and fellowship as next steps in ease of research.
We must also ensure that our scientific workforce—PhD students and postdoctoral fellows—receive uninterrupted fellowships throughout the duration of their training. @DBTIndia @CSIR_IND @IndiaDST @ICMRDELHI @PrinSciAdvGoI @insa_academy @IAScBng .
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It is crucial to understand the raw data and present it in a way that accurately reflects its nuances. Some cool stuff in this paper to take it to the next level.
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"Academia, in its best form, can feed your stomach, brain and heart." These words resonate so deeply. A great thread for everyone pursuing or wishing to pursue an academic career in India.
Today, I complete 15 years as a faculty member at #IISERPune. I have attempted to put together a list (based on my blogs) of some lessons that I have learnt so far. A disclaimer to note is that this list is by no means a comprehensive one, but a text of self-reflection from my.
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RT @IndAcadNeurosci: It’s time for the much awaited Annual meeting of Indian Academy of Neurosciences. This year the IAN-2025 is @RGCB_Triv….
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Thrilled to be spending the next few days @ENSdeLyon as BIOSANTEXC Discovery program grantee. Looking forward to engaging in scientific discussions with @MollereauLab and sharing our work during the upcoming "Mini-symposium on Neurodegeneration." @tvmiiser
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n/n- Lastly, there is no one formula to succeed in the interviews. Different committees and institutes are looking for different skills. A rejection doesn’t mean you are a bad candidate. It may simply mean you may be a better fit elsewhere. Best wishes to all of you.
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9/n- Afterwards—After the interview, note down the key learning points. Even if one interview didn’t go great, don’t beat yourself up over that. Take some time and focus on the next interview.
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8/n- Language- Most interviews are conducted in English. However, if you are more comfortable in another language, you may request the committee. If the committee has any member who speaks that language, there is a good chance they will help you out.
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