The first paper from my research group is published! We engineer the first cell cycle reporters in primary human intestinal monolayers, design a collagen press for optimal imaging, and compile a computational pathway for image analysis. https://t.co/inMgjYKfSt

Our pre print is available now! @JimWellsLab @CuSTOMOrganoids

Check out this great paper from @MikeVerzi that @magnesslab and I helped with showing how TGFB1 affects the intestinal epithelium through the Sox9 axis. It was a beast of a project before we joined and I'm glad we could help flesh out the mechanism!

The first manuscript from the Burclaff Group is live as a preprint! See our engineered platform, cell constructs, and computational analysis pipeline for visualizing and measuring cell cycle phases in primary human intestinal stem cells!

Also check out @JosephBurclaff new paper on Sox9 and cell cycle. Cool stuff!!

Here is some of the work highlighted showing that Sox9 is necessary to maintain the reserve #stemcells

We are excited to introduce our incoming co-editors-in-chief, Drs. Michele Battle and Jonathan Katz! Read more of our announcement ➡️ https://t.co/QnOwEcbCAc

Join FASEB for the inaugural Gastrointestinal Epithelium Conference on September 17 in Colorado. This will be the best venue for researchers of the lining from the esophagus to the colon. #GESRC @BeyderLab @squeakyanimal Register: https://t.co/k0XEaTkVSo

Scott Magness @magnesslab with Misty Good was awarded 1M by the @ChanZuckerberg Initiative to establish a single-cell atlas of rare inflammatory pediatric disease. "Early biomarkers are lacking currently, but offer hope for identifying and preventing NEC." https://t.co/lkSG3NT4Cl

Also... Check out the newly updated Magness Group Website!

https://t.co/y7KGemP1ct

What happens to human intestinal stem cells during hypoxia? Rivera & Bliton et al from the Magness Group build a microphysiological hypoxia system, assess ISC viability, HIF1a, transcriptomics during acute/chronic hypoxia and show hypoxia primes ISCs for interleukin responses.

Also... Check out the newly updated Magness Group Website!

https://t.co/4Lf0l37O1t

Meryem Ok et al in the Magness Group show C. diff receptor expression in single cells across the human gut, transcriptomic differences in primary colonocyte and Caco2 maturation, a 2D colonic cell system to evaluate TcdA/B, demonstration of uncoupled apical/basal toxicity. 👍

@TaniguchiMD @JosephBurclaff @magnesslab

The lab of @AlexandervanOu1 developed two new methods to study chromatin in single cells. Researchers can use these methods, published in @NatureBiotech and @NatureGenet, to increase our understanding of chromatin regulation during development. https://t.co/vN6qoF9isO

Very excited that our intestinal atlas is included in the top 15 high impact basic science articles of 2022 by @AmerGastroAssn! Congrats to everyone else included on the list! It was a good year for GI research!