Mercurio Lab
@lab_mercurio
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Official twitter feed of the Mercurio Lab at the University of Massachusetts Medical School
Worcester
Joined July 2019
The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing
cell.com
Mukhopadhyay et al. report that TRPC6, a cation channel that mediates calcium entry, distinguishes cancer stem cells from other populations in breast cancer and that it sustains their function. Tumor...
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Thrilled to share our recent paper published online @CellReports led by our graduate student Dimpi @Mukherjee4D 🎉 @UMassChan @UMassCancerCtr @UMassChanMCCB @UMassChanGSBS
https://t.co/qMgf7kPEfV
cell.com
Mukhopadhyay et al. report that TRPC6, a cation channel that mediates calcium entry, distinguishes cancer stem cells from other populations in breast cancer and that it sustains their function. Tumor...
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So proud of our lab's work!! @lab_mercurio
The @lab_mercurio discovers that #Neuropilin2 presents a promising treatment target in #ProstateCancer, showing that targeting its connection to VEGF with an antibody sensitizes normally-resistant tumors to #PDL1 immunotherapy in mice. @UMassChanSOM
https://t.co/tQgyupFKxQ
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New Science Translational Medicine Publications!
mercuriolab.umassmed.edu
Our assistant professor Hira Goel also published in collaboration with aTyr Pharma “Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative...
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It is with deep sadness that we share Michael Green, MD, PhD, has died. Please honor his legacy by reading about his work as one of the most distinguished biomedical research leaders in our academic community and across the nation:
umassmed.edu
Joint statement from Chancellor Michael F. Collins and Dean Terence R. Flotte on the death of Michael Green.
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Last week Mandy presented her poster at the 2022 Cell Bio Conference in Washington DC!
mercuriolab.umassmed.edu
The 2022 Cell Bio Conference in Washington DC hosted by the American Society for Cell Biology (ASCB) and the European Molecular Biology Organization (EMBO) featured advances in multiple areas of cell...
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The annual commencement proceedings returned to the UMass Chan Medical School campus in Worcester on Sunday for the first time in three years in a jubilant gathering. We have more photos posted here: https://t.co/3XBtg9lYQj
#UMassChan2022 @UMassChanSOM @UMassChanGSBS @UMass
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Congratulations to these newly minted PhDs from the Morningside Graduate School of Biomedical Sciences! #UMassChan2022 @UMassChanGSBS
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First in-person conference ✅ with the best bunch!!
Learned a lot from all these great scientists at the @FASEBorg #CSCSRC22 meeting on Cell Signaling in Cancer in New Orleans this week. Thanks for a great week and for organizing @bradylabupenn @VickySanzMoreno @DarArvin and Jorrit Enserink. With @JuraLab_UCSF @Ed_Linossi
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Dimpi Presents at The Cell Signaling in Cancer Conference: From Mechanisms to Therapy
mercuriolab.umassmed.edu
Graduate student Dimpi Mukhopadhyay was selected to give a short talk on her current work at The Cell Signaling in Cancer Conference: From Mechanisms to Therapy, hosted by the Federation of American...
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Spotlight on an unexpected role for PD-L1 in front–rear polarization and directional migration
mercuriolab.umassmed.edu
Our recent publication, PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics , was highlighted by Sánchez-Álvarez and del Pozo in a JCB this week! You can...
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New Spotlight: Sánchez-Álvarez @bio_miguelon & del Pozo @madelpozo67 highlight work by @lab_mercurio ( https://t.co/f5hQ61uU1Q) that shows that PD-L1 promotes front–rear polarity and migration independently of PD-1 https://t.co/BpDSdVCwVr
@CaveoLab @CNIC_CARDIO #Cancer #Migration
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Dr. Walker was recently invited to discuss her publication with a group of MIT trainees interested in glycobiology.
mercuriolab.umassmed.edu
Recent graduate, Dr. Melanie Walker, met with the MIT Glycobio Club on April 6th to discuss her recent publication O-linked α2,3 sialylation defines stem cell populations in breast cancer. Dr. Walker...
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Video: PD-L1 and β4 #integrin co-localize at “roots” of retraction fibers during cell migration. Wang, Xiong and Mercurio @lab_mercurio @UMassChan show that PD-L1 promotes rear retraction during persistent cell #migration by altering integrin β4 dynamics https://t.co/f5hQ61uU1Q
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Some of our recent work was presented at the annual AACR meeting this past week!
mercuriolab.umassmed.edu
Recent Mercurio Lab work was a part of two presentations at the annual American Association for Cancer Research meeting. Graduate student Emmet Karner presented on ferroptosis resistance in epithel...
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