🚨 1/ NEW PAPER in @NatureComms https://t.co/G2Jl7h1oAN Can we define lymphoid-competent HSCs across age? What drives their fate — and is it conserved? We uncover a rare, lymphoid-primed HSC subset with immune regenerative power across lifespan. 🩸👇🧵

HAPPY 4th and excited to be part of this. Congrats to the talented Dr. Harold Elias @hrldelias for getting this epic Nature Comm story https://t.co/0c2MpoFood on how kitlow HSCs have superior thyme reconstitution. Big congrats to @DrMvandenBrink and collaborators @mskcc.

🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! @epicypher @FuksLab https://t.co/SYynz5fyxi

Excited to announce that we are starting to look for a Lab Manager for our group! Let me know if you are interested in joining!

So proud of this incredible work from @GauravA_UK from our group with help from many fantastic folks in our lab and inspiring collaborators, including @KharasLab, @AlexBickMDPhD, @yash_pershad, @_ruslansoldatov, @AbdelWahablab. Please check it out 👇👇

Hey ALL for the time our lab is has its own team KHARAS LAB! @Cycle4Survival to raise money for rare cancer research at @MSKCancerCenter, and your support would mean so much to us. Make a 100% tax-deductible donation using the link. Thank you so much!

ChromaFold predicts the 3D contact map from single-cell chromatin accessibility @NatureComms 1. ChromaFold introduces a deep learning model that predicts 3D chromatin interactions using only single-cell ATAC sequencing (scATAC-seq) data, bypassing the need for expensive,

Thrilled to share our paper now out @Nature delineating #plasticity during #CRC #metastasis, a fantastic collaboration led by @andrewrmoorman @elliebenitez11, and @f_cambuli from the @KarunaGaneshLab and @dana_per lab! https://t.co/NYQRHfq3gz https://t.co/Z4GFwqL8G2. A 🧵

This causes HSCs to divide & make red cells. Julia didn't discard repetitive sequences when comparing gene expression in HSCs from pregnant vs non-pregnant mice & humans: retrotransposons came on in pregnant HSCs. Nobody had noticed this because rep seqs are usually discarded 2/5

📢Thrilled to announce that I will start independent position at Fox Chase Cancer Center Jan 2025 @CeiFccc @FoxChaseCancer. The Luo lab will study novel #mechanisms controlling stem cell fate choices in normal and diseases. 🧬🔬🐁🩸#RNA #RNAmodifications #HSC #leukemia (1/4)

We posted an update to "A transposase-derived gene required for human brain development" including additional patient families with PGBD5 deficiency syndrome and mouse model studies for its unanticipated (neuron genome remodeling!) mechanism of action:

Our team @SCICambridge is expanding and we have now a very exciting opening for a Laboratory Research Technician/Assistant!!! More positions to be announced very soon. Help us spread the word 👇👇🔬🔬 https://t.co/U4qdvpvFWx

Read the In the Spotlight commentary by @KharasLab, Dotting out AML by targeting Fibrallarin, discussing a recent @NatureCellBio paper from Pengxu Qian et al. https://t.co/1rqrowpBTn

🎉It's Gilliam Day! 🎉 We're so excited to announce the 2024 #GilliamFellows! These 50 adviser-student pairs are being recognized for their outstanding research as well as their commitments to advancing equity and inclusion in science.

GoT-ChA! I am thrilled to announce that our paper "Mapping Genotypes to Chromatin Accessibility Profiles in Single Cells" is now out in @Nature !! 👩‍🔬👨‍🔬🧬If you want to link somatic mutations to epigenetic changes directly in patient samples: https://t.co/M9Y3wEvpuW 👇🧵

Also a link to @nature for this work: https://t.co/36E1WoGf0G We have already helped ~15 labs get going on GoT-ChA, ping us if we can be of any help

Read our latest on epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas:

@ramith__ This is addicting, just made a song about RNA and splicing 😅 https://t.co/9vy9S9jFo0

A fantastic initiative spearheaded by @IfeAkano, my superstar @WeillCornell @MSKCancerCenter graduate student, to provide a safe space to discuss resilience as part of a path to wellness. 🔥Happening this Thursday- please register! Thank you @HHMINEWS Gilliam for supporting!🙏🏻

Thrilled and proud to share the new paper from the lab @NatureComms https://t.co/MiGukymC57 A shout out for the awesome editorial team @NatureComms and reviewers for my best experience with publishing. Grateful to all authors, special thanks to my lab. @ubcpharmacy @BCCancer