kaeli mathias
@kaeli_mathias
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phd student @BMBGGUPENN, working with @LilingWanLab and @MustafaMir16
Joined January 2020
We’re excited to share that, after receiving many requests each year from the research community for Oligopaint DNA & RNA FISH probes, we’re piloting a service to design & prepare probes for labs. Please share with colleagues who may benefit!
ericjoycelab.com
In an effort to make Oligopaint FISH probes more broadly available to the research community, we offer DNA and RNA FISH probe design, synthesis, and generation. By dedicating a full-time staff memb…
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1/n) Excited to share our new preprint: Using high-res live embryo imaging we show that transcription factor hubs are localized to new genes when specific DNA binding is perturbed. Hub interaction kinetics at these new sites determine factor occupancy: https://t.co/ZkNklKMgTV
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Congratulations our student @kaeli_mathias for being awarded the Patel Family Cancer Research Scholars Award!
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Fun labor day celebration with the lab and partners!
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Excited to announce I have been awarded an F31 from the NCI! Incredibly grateful for the excellent mentorship and guidance from @LilingWanLab and @MustafaMir16 and all the support from my lab mates in these two great labs. Special thanks to all those who helped along the way!
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Incredibly honored to be selected as a Freeman Hrabowski scholar along with so many outstanding early career scientists. We are excited to use this support to continue to ask big questions while improving the scientific work environment for all. Thank you @HHMINEWS #FHScholars
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Congratulations to Dr. Mustafa Mir for being selected as an @HHMINEWS Freeman Hrabowski Scholar! Learn more about the honor + Dr. Mir's research on Cornerstone: https://t.co/Hjos18FtWa
#FHScholars
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It's been a great year in the #Mirlab from setting up our MOSAIC microscope to visualizing how proteins navigate the crowded nuclear environment in live embryos during development in real time! Stay tuned for more stories! ;) #FluorescenceFriday #drosophila #latticelightsheet
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Happy #FluorescenceFriday! It's been so fun learning light sheet microscopy in @MustafaMir16's lab🔬 Transcription factor (green) dynamics during nuclear divisions in the early fly embryo 🪰🧬
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Congrats to @kaeli_mathias for winning both the People's Choice and Best Application poster awards at our @CHOP_CCGM center retreat this weekend!
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Ft'd on the cover of @MolecularCell, new research provides insights into mutant ENL condensate formation ft. Lele Song, Hangpeng Li, @alanboka1, Yiman Liu, @kaeli_mathias, Lingbo Xia, Qinglan Li @MustafaMir16 & @LilingWanLab @Penn_CBIO @PennCBP @PennCancer
https://t.co/uTZPWPuiYr
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Wonder how transcriptional condensates form? Are they causal to function? disease implications? Check out our new study out @MolecularCell we provide insights into these questions by investigating a series of mutations in the chromatin reader ENL (1/n)
cell.com
Song et al. show that ENL cancer mutations trigger aberrant condensate formation at genomic targets through multivalent homotypic and heterotypic interactions and in a dose-dependent manner. Pertur...
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Dance of the Histones (ft. several nuclear divisions inside a live #Drosophila embryo during development taken on our MOSAIC system earlier this year). Sound on! and happy #FluorescenceFriday :)
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(1/n) First tweetorial so hopefully I did this right. our paper on targeting chromatin reader ENL is out @CD_AACR. we developed an in vivo bioavailable ENL inhibitor, demonstrated its efficacy in molecularly defined AML, and determined its mechanisms
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Congratulations to @kaeli_mathias from the @MustafaMir16 lab for receiving the Genetics Training Grant!
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Congratulations to @kaeli_mathias (co-mentored w/ @MustafaMir16) for passing her prelim @BMBGGUPENN and becoming the first Ph.D. candidate in the lab! so proud of you and can't wait to see great things you will accomplish in the next few years! #ProudPI #WomenInSTEM
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Congrats @kaeli_mathias. Very proud of our first PhD candidate & looking forward to all the awesome discoveries you will make. 2 labs = 2x the fun!
Congratulations to @kaeli_mathias (co-mentored w/ @MustafaMir16) for passing her prelim @BMBGGUPENN and becoming the first Ph.D. candidate in the lab! so proud of you and can't wait to see great things you will accomplish in the next few years! #ProudPI #WomenInSTEM
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Thanks to the Margaret Q Landenberger foundation for funding our research on studying the molecular dynamics of gene regulation! We are still looking for more postdocs to join us on our adventures. Please DM or email me if you are interested and help spread the word!
Congratulations to Mustafa Mir (@MustafaMir16) on receiving a Margaret Q Landenberger Research Foundation grant to study the molecular dynamics of gene regulation during development and in cancer! 🎉🏆🥼
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NEWS: Amherst College is ending the longstanding practice of a legacy admission preference and expanding its financial aid investment to $71 million per year. These changes will assure an Amherst education is within reach for all. https://t.co/gpH0wcVslT
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Congratulations to @MustafaMir16 (@PennCDB/@CHOP_CCGM), recipient of the @NIHDirector's New Innovator Award!🎉 Learn more about Dr. Mir's project https://t.co/WCsIs7iA5V and research interests here https://t.co/We1UpoVeGK
#NIHHighRisk
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