Lab of Synapse Biology
@joris_dewit_lab
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Laboratory at VIB-KU Leuven Center for Brain & Disease studying synapse development and neural connectivity. Team-managed account.
Leuven, Belgium
Joined August 2020
Glad to see our new paper finally out! We show how the GPR158 receptor controls synapse maturation and function by silencing an intrinsic inhibitory mechanism. https://t.co/pRYbizdEph Work from Ben Verpoort and colleagues, with special thanks to our collaborators.
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Postdoc opportunity in the heart of Europe! Check out the flyer below. Join our team on an international project with Anthony Holtmaat @teuntoonenaug exploring synaptic plasticity and specificity in cortical and thalamocortical circuits.
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🧠 The team of @joris_dewit_lab and colleagues discovered how 'synaptic signatures' in specific brain cells (in a mouse model) could contribute to neurodevelopmental disorders. @CBD_VIB @FWOVlaanderen @KU_Leuven Read here 👉 https://t.co/IyTyE18bll
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We continue the #BrainMosaic24 Poster Pitches🎬 with Dan Dascenco @DDascenco of @joris_dewit_lab / @CBD_VIB. He shows that CRISPR-tagged synaptic proteins reveal vital factors in synapse development and connectivity. ▶️Watch his pitch to find out more.
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Today Dr. Joris de Wit @joris_dewit_lab from @CBD_VIB offered us a fantastic #SeminarsIN about the synapse biology in the ‘omics age’. Great talk, thank you 👏
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For our latest Colleague with a Story we chat with @artemiskoum, postdoctoral researcher in the @joris_dewit_lab and Executive Director at @TReNDinAfrica, a non-profit organization supporting scientific capacity-building across Africa 🚀↘️ https://t.co/56SPOl5nPn
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📢Big news, please RT🎉 I will be starting as a TT Assistant Professor (W2) of Neuroscience at @LMU_Muenchen in April 2025! The Schroeder lab will study how the brain 🧠 generates internal states, and then uses this information to adapt behavior in dynamic environments. 👇A🧵
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⏰ Are you conducting research in #neuroscience and want to present your findings to the leading scientists at #BrainMosaic24? Submit your abstract before the 8 August deadline. @NatureNeuro will offer a poster prize 🏆! Submit your abstract here: https://t.co/1zwVRKOAYW
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💡 @SFARIorg has awarded grants to @joris_dewit_lab and @VanderhaeghenP2, researchers at @CBD_VIB, to facilitate research into the neurobiological underpinnings of #Autism Spectrum Disorder. Find out more ➡ https://t.co/IzOQAwM6CM
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Just posted! https://t.co/i69XhsTf8t. How do #neurons wire up during #development at the right time in the right place? We looked at glutamatergic excitatory synapses in the hippocampus in vivo and found an unexpected role for NMDA receptors in a very early ‘critical window’🧵
biorxiv.org
The rules governing neural circuit formation in mammalian central nervous systems are poorly understood. NMDA receptors are involved in synaptic plasticity mechanisms in mature neurons, but their...
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🗞️ New paper driven by @reMYNDnv with involvement from labs at @CBD_VIB published in @ScienceMagazine discovers a pharmacological intervention that restores calcium homeostasis and acts as a protective mechanism in models of #Alzheimers. Find out more 👉 https://t.co/0ZKXbY8z8H
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#ScienceDay 2024 was a blast! 🚀 Yesterday @CBD_VIB employees came together for our annual day of talks, networking and activities to spark new research ideas and foster our vibrant community spirit ✨
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New preprint out from our lab! We uncover a novel mechanism that regulates synaptic organelle content of dendritic spines, important for the proper maturation of cortical connectivity. https://t.co/La63ufTTLg
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Looking for a weekend read? 🌞 📚 In this #review, scientists from the @joris_dewit_lab provide an overview of the intracellular 🚦 signaling pathways that are engaged by #synaptic cell adhesion molecules. https://t.co/3HlShhjJzw
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🏆 Stichting Alzheimer Onderzoek - Fondation Recherche Alzheimer selected 15 research projects from VIB this year to invest a record amount of 3️⃣ million euros! Congratulations to all 👏 @CBD_VIB @CMN_VIB @InflamResCen
https://t.co/D2M121d07l
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🤝 This month, we teamed up with @TAJO to inspire young people to get interested in neuroscience! We touch base with the researcher volunteers from @Verstreken_Lab × @joris_dewit_lab and TAJO educators to find out more about their experience ⬇️ https://t.co/XmZtmrqsVq
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New insights into cortical layer 5 neurons! @_gabmas work reveals unique synaptic signatures of L5 IT and PT neurons in somatosensory circuits. Molecular profiles hint at specialized roles, with L5 IT showing enrichment of autism risk genes. https://t.co/7tezgO6LlX
biorxiv.org
Cortical layer 5 (L5) intratelencephalic (IT) and pyramidal tract (PT) neurons are embedded in distinct information processing pathways. Despite their significance for cognitive function, it remains...
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👀Check out the @BioCentury feature on the research from the teams of @VanderhaeghenP2 and @joris_dewit_lab! If you’re interested in learning more about this exciting breakthrough, you can read our full article here 👉 https://t.co/JsKIDVW8F5.
cbd.sites.vib.be
Stay up-to-date with the latest news from the Center for Brain & Disease Research | Neuroscience in Leuven, Belgium
Voltage-gated sodium channel insights outside of pain. Researchers link Nav1.7 to osteoarthritis progression and identify a modulator of Nav1.6 for epilepsy.
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