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Dr Joanna Moncrieff Profile
Dr Joanna Moncrieff

@joannamoncrieff

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Critical psychiatrist, author and researcher. Also @joannamoncrieff.bsky.social

UK
Joined October 2013
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@joannamoncrieff
Dr Joanna Moncrieff
8 months
Following the storm of interest provoked by our 2022 review, I am pleased to announce the publication of my book telling the story of the serotonin theory of depression from the beginning to recent times. Due out Jan 2025. To pre-order @flint_books 1/3
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@joannamoncrieff
Dr Joanna Moncrieff
3 hours
Thanks for highlighting this - a very important issue.
@CarlatPsych
Carlat Psychiatry
9 months
In a survey of sexual+gender minority youth, excluding people with hormonal treatments, 1 in 7 experienced PSSD symptoms after stopping antidepressants, 14 times the rate in youth who had stopped other psychiatric medications. #mentalhealth RT @markhoro
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@joannamoncrieff
Dr Joanna Moncrieff
3 hours
Totally accept your point. It is v. difficult to get funding to do research on adverse effects e.g. withdrawal. Here is one paper we did looking at experiences of antidepressant withdrawal in people in online groups - it showed how severe it is for many
@angpeacock1111
Angie Peacock, MSW, CPC
21 hours
@Rozewicz @JAMAPsych @markhoro @joannamoncrieff We have thousands of patients in online communities and deprescribing practices that NO ONE is studying. Lots of media about this, documentaries, videos, even some of your own journal articles talk about it:
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@joannamoncrieff
Dr Joanna Moncrieff
4 hours
The fact the review is interpreted as ‘reassuring’ by its authors is concerning, and suggests future patients may not be properly informed about the risks of antidepressants 5/n.
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@joannamoncrieff
Dr Joanna Moncrieff
5 hours
The criterion of 4 plus symptoms to indicate clinically significant withdrawal, although suggested by others, is arbitrary and has no empirical basis – 1 severe symptom could be disabling and could also obscure other symptoms 3/n.
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@joannamoncrieff
Dr Joanna Moncrieff
5 hours
On the other hand, the data on the incidence of individual symptoms is completely unreliable because it includes data from spontaneously reported adverse events, which are not collected systematically, and highly likely to miss cases 2/n.
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@joannamoncrieff
Dr Joanna Moncrieff
5 hours
The new review of antidepressant withdrawal has some merits: in trials using systematic measurement, it shows SSRIs and SNRIs cause withdrawal symptoms even after a few weeks of use. Agomelatine doesn’t (this is already recognised) 1/n
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@joannamoncrieff
Dr Joanna Moncrieff
5 hours
RT @lizctucker: My latest Substack article highlights my podcast with @LauraDelano who diagnosed as bipolar at 14, discusses how the medica….
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@joannamoncrieff
Dr Joanna Moncrieff
5 hours
As I was leaving a meeting today someone I don't know approached me to tell me her mother is in severe antidepressant withdrawal. Anecdotal, of course, but suggests this experience is not uncommon.
@AnnaKin06551830
Anna King
15 hours
Attached is a montage of 8 individuals who share their lived experience of Antidepressant Withdrawal. Their symptoms are not mild or transient & their exposure to ADs is far beyond 6-12 weeks. They represent the real-life experience of AD withdrawal.
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@joannamoncrieff
Dr Joanna Moncrieff
5 hours
RT @MichelleFunk3: Thank you so much @markhoro for putting the new data into context with clear, evidence-based analysis. You highlight tha….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
RT @BioProtocol: @joannamoncrieff The gap between short-term studies and real-world long-term use is massive, and honestly, it’s frustratin….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
RT @ReadReadj: New Scientist includes critique by ⁦@markhoro⁩ and myself of this flawed study irresponsibly minimising antidepressant withd….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
This thread highlights the severe limitations of the recent review of antidepressant withdrawal.
@markhoro
Mark Horowitz @markhoro.bsky.social
1 day
The review by Kalfas on antidepressant withdrawal in JAMA Psychiatry will mislead as it is based largely on people who have taken antidepressants for 8-12 weeks in 11 RCTs-this will under-estimate the risks for millions of long-term users. Thread (1/n)
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
RT @markhoro: Looking at what happens to people after 8-12 weeks is the equivalent of a car company running a crash collision of its cars b….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
This is what's wrong with minimising antidepressant withdrawal.
@cwestonclark
Carrie Clark
2 days
According to @markhoro, @sameerjauhar will publish an article tomorrow calling for antidepressant withdrawal to be deemphasised in clinical guidelines. This is a huge gut punch for those of us in the prescribed harm community who are trying to raise awareness about the risks of.
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
RT @markhoro: Useful article on long-lasting antidepressant withdrawal injuries from @NPRHealth including showing people who have delayed o….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
and note the only longer term trial (26 weeks) was of agomelatine, which seems to cause substantially less physical dependence.
@markhoro
Mark Horowitz @markhoro.bsky.social
1 day
The review by Kalfas on antidepressant withdrawal in JAMA Psychiatry will mislead as it is based largely on people who have taken antidepressants for 8-12 weeks in 11 RCTs-this will under-estimate the risks for millions of long-term users. Thread (1/n)
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
RT @markhoro: In the NYT, academics, some of whom have been paid by companies that market these drugs, say that patient concern about withd….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
RT @markhoro: Concluding that depressed mood following antidepressant withdrawal was relapse "could lead clinicians to neglect or misjudge….
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
'Studying what happens to people after just eight to 12 weeks on antidepressants is like testing car safety by crashing a vehicle into a wall at 5km/h – ignoring the fact that real drivers are out on the roads doing 60km/h'
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@joannamoncrieff
Dr Joanna Moncrieff
1 day
Article about a new review on antidepressant withdrawal: 'the new research relied on short-term drug company studies of just a few weeks, which bore little resemblance to patients who had been taking antidepressants for many years'
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