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Mark Horowitz @markhoro.bsky.social Profile
Mark Horowitz @markhoro.bsky.social

@markhoro

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Trainee psychiatrist/Researcher @NELFT @UCLPsychiatry (honorary) . Maudsley Deprescribing Guidelines: https://t.co/MdD00q9Yd1 (US) https://t.co/9eUVpPj52p (UK)

London
Joined April 2013
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@markhoro
Mark Horowitz @markhoro.bsky.social
1 year
The Maudsley Deprescribing Guidelines is available in the UK US Australia Canada elsewhere around the world (also at other booksellers).
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@markhoro
Mark Horowitz @markhoro.bsky.social
23 minutes
This statement is derived from studies of people who have been on the drugs for 8 weeks and in which severity was not measured and extrapolated to all users of antidepressants
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@markhoro
Mark Horowitz @markhoro.bsky.social
31 minutes
RT @joannamoncrieff: 'Studying what happens to people after just eight to 12 weeks on antidepressants is like testing car safety by crashin….
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@markhoro
Mark Horowitz @markhoro.bsky.social
32 minutes
RT @EllenBarryNYT: Comments are open on this piece on antidepressant withdrawal and a new analysis suggesting that withdrawal symptoms are,….
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@markhoro
Mark Horowitz @markhoro.bsky.social
33 minutes
RT @joannamoncrieff: This thread highlights the severe limitations of the recent review of antidepressant withdrawal.
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@markhoro
Mark Horowitz @markhoro.bsky.social
55 minutes
RT @JDaviesPhD: The New York Times were not taken in by the PR campaign pushing the new antidepressant study (a study mostly denying antide….
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@markhoro
Mark Horowitz @markhoro.bsky.social
56 minutes
RT @joannamoncrieff: and note the only longer term trial (26 weeks) was of agomelatine, which seems to cause substantially less physical de….
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@markhoro
Mark Horowitz @markhoro.bsky.social
56 minutes
press release 'presenting the data': "Now, this cutting-edge review clarifies the scientific evidence and should reassure all parties about the use, and discontinuation, of these treatments. Official guidance should now be changed to reflect the evidence."
@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
They presented data from 8-12 week trials, concealed that in the paper (zero mention of length) and called for guidelines to be re-written in their press release for millions of long term users. That is not "just presenting data" Data here:
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@markhoro
Mark Horowitz @markhoro.bsky.social
1 hour
Dr Lewis “We do see supporting evidence for the experience of withdrawal symptoms after antidepressants are stopped. However, by the 12-month follow up, there’s very little evidence of a difference,” Only 12 months of withdrawal on average, no issue here!
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
They presented data from 8-12 week trials, concealed that in the paper (zero mention of length) and called for guidelines to be re-written in their press release for millions of long term users. That is not "just presenting data" Data here:
@sameerjauhar
Sameer Jauhar
22 hours
As before, incorrect. Just presenting data. Polarisation is wrong, in any context. See what you think of the paper. Regards, Sameer.
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
Concluding that depressed mood following antidepressant withdrawal was relapse "could lead clinicians to neglect or misjudge these symptoms, leading to longer-than-needed use of medication for some patients."
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
In the NYT, academics, some of whom have been paid by companies that market these drugs, say that patient concern about withdrawal was caused by a 2019 review of withdrawal and is manufactured
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
RT @ReadReadj: Antidepressant withdrawal: new review downplays symptoms but misses the mark for long-term use via @….
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
Very common story - delayed onset withdrawal effects often occur.
@i_r_wilson
Andy Wilson
2 hours
@markhoro I can't access the full paper. It says in the summary that this was looking at symptoms after 1 week off the medication. Is that correct? It seems like a massive limitation. The first week off the drugs for me was relatively mild compared to how I was a few months later.
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
The review by Kalfas on antidepressant withdrawal in JAMA Psychiatry will mislead as it is based largely on people who have taken antidepressants for 8-12 weeks in 11 RCTs-this will under-estimate the risks for millions of long-term users. Thread (1/n)
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
"Scientists accused of downplaying dangers of antidepressants"
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Mark Horowitz @markhoro.bsky.social
2 hours
RT @KyCryxpto: @sameerjauhar “Presenting the data” that you know full well is compromised like that in the Antler trials by misclassifying….
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
When denial of the issue is no longer tenable they turn to minimisation and underplaying. See @ConversationUK article here: (31/n).
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
It is hard not to think of Naomi Oreskes book ‘Merchants of Doubt’ in which she outlines how academics backed by industry have set out to deny, obscure and minimise health and environmental issues, including links between smoking and cancer. (30/n).
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@markhoro
Mark Horowitz @markhoro.bsky.social
2 hours
This may have the effect of diminishing the already paltry efforts by the health system to help 10,000s of people who are suffering and much greater numbers at risk of serious issues. (29/n).
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