Jennifer E Wu
@jenewu1
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Senior Scientist @Regeneron | PhD @WherryLab immunologist, cocktail enthusiast, native Californian
Tarrytown, NY
Joined October 2019
In vitro models of CD8 T cell exhaustion make high-throughput interrogation easy, but can they be used to discover real Tex biology with therapeutic relevance?. Read to find out! In our new work from the @EJohnWherry lab, out now at @SciImmunology, we.
science.org
CRISPR screening in an in vitro model of CD8 T cell exhaustion identifies BHLHE40 as regulator of T cell differentiation.
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RT @megclarks: Thrilled to share our paper on how mitochondrial complex IV remodeling can modulate TAM functions and promote anti-tumor imm….
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RT @megannn_lynne: Didn’t even get a Roaring 20s before this Great Depression. I got fucking grad school.
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If you read one paper this week, make it this one!! Gorgeous mechanistic work—detailing how TOX not only initiates but maintains the cell fate of exhausted CD8 T cells—by an extremely talented scientist and good friend @jane__huang.
Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below!.
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RT @jane__huang: Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fat….
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RT @CancerResearch: Cancer research cannot wait! In response to @NIH uncertainty & funding cuts, we’re committing $2.5M to support 10 addit….
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RT @UPENN_ITMAT: Rewiring exhausted T cells to create therapeutic innovations for #ChronicInfections & #CancerTreatment .
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RT @subaita_rahman: I’d never imagine seeing a pipette in a museum but I’m glad it’s the one that saved the world
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RT @thatsdrpox2you: So excited to share that the research I've been working on the last few years in @montserrat lab is out now in @SciImmu….
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RT @EJohnWherry: Very happy to share this new work on LAG3 and PD1. Has been a long road to (begin to) sort out how LAG3 functions in CD8 T….
cell.com
LAG-3 loss modulates PD-1 deficiency by regulating TOX transcription factor expression in exhausted CD8+ T cells and their responsiveness to cellular stress in target cells.
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RT @parkerici: New research from @PennMedicine in @ScienceMagazine, led by PICI Investigators, shows promising results for advanced #NSCLC….
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RT @s_apostolidis: We are currently looking for a motivated Research Specialist to join the Apostolidis Lab! If you're passionate about und….
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RT @divijmathew: extremely excited to share our new story on the impact of JAK inhibition on responses to immune checkpoint blockade in lun….
science.org
Persistent inflammation driven by cytokines such as type-one interferon (IFN-I) can cause immunosuppression. We show that administration of the Janus kinase 1 (JAK1) inhibitor itacitinib after...
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RT @M_S_Hakeem: Hakeem Lab is hiring a Visiting Fellow! . Come join our team @PATRU_Emory @EmoryVaccineCtr @EmoryUniversity!. At least 2 y….
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RT @Lukeocyte_bio: Excited to announce the publication of my PhD work with @metaBailism in @SciImmunology! Many thanks to the lab and coll….
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RT @thatsdrpox2you: My postdoctoral research in @monsterrat lab is now on Biorxiv! We delve into mechanics of X Chromosome Inactivation (XC….
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RT @KellyKersten8: I’m hiring a postdoc and SRA for my new lab at @sbpdiscovery in San Diego, CA! Are you passionate about dissecting the i….
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