Itamar Lev
@itamar_lev
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Very happy our teams story (@Toker_IA @YaelMor3) is finally out! Even transient transgenerational effects can have an impact on evolutionary processes. great-grand progeny of stressed worms inherit the ability to produce male attracting odor, increasing their chances of mating.
Our “Distracted Worm” paper is finally published! Can transgenerational RNA inheritance bias crucial behavioral decisions for multiple generations? Read how stress controls the progeny’s mating preferences by boosting attractiveness 🔥💥👇 https://t.co/weatuVCEJs
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BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has
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A super cool story from Ethan and the @OdedRechavi , O2-sensation-related, neuronal small RNAs regulate germline DNA damage and fertility in high temp!🔥
WOoo! Hot pre-print alert! 🔥 Our new story shows that neuronal oversight of germline small RNAs prevents sterility & allows lab-domesticated C. elegans to reproduce when temperatures rise. This picture shows how neuronal small RNAs rescue the germline from being messed up (1/2)
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rRNA intermediates dictate nucleolar architecture in C. elegans
biorxiv.org
The nucleolus is a multilayered, membraneless organelle essential for rRNA transcription, processing and ribosome assembly; however, it remains largely unclear whether and how these molecular events...
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Molecular profiling of adult C. elegans glia across sexes by single-nuclear RNA-seq https://t.co/rP6unf59qn
cell.com
Purice et al. present single-nuclear RNA-seq profiling of adult C. elegans glia by sex (wormglia.org) with custom computational analytics, and identify glial heterogeneity, molecular markers, and sex...
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Last year, we posted a preprint providing the first genetic evidence that the Harbin skull likely belonged to a Denisovan: https://t.co/DSsB6tkkM7 Today, DNA evidence provided the final proof: https://t.co/guMUY7k8lx
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Divergence in neuronal signaling pathways despite conserved neuronal identity among Caenorhabditis species https://t.co/6zBcf4XQEo
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📄 New paper: "A Minimum Description Length Approach to Regularization in Neural Networks" with Orr Well, Emmanuel Chemla, @roni_katzir, and @nurikolan . We explore why neural networks often struggle with simple structured tasks. Spoiler: our regularizers might be the problem. 🧵
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Flatworms, but make it high-res. 🧠🪱 This new protocol combines tissue expansion + light-sheet microscopy to reveal planarian neural and muscle anatomy in 3D, at single-cell resolution. #Planaria #Microscopy #DevBio
https://t.co/ng3wTyhzW9
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🔥🔥🔥OUR NEW PREPRINT: Slowing and reversing aging? Nature does it, here we show how! Age deceleration and reversal gene patterns in dauer diapause. Huge congrats to Kristy Totska, João Barata, Walter Sandt and @Meyer_DH
biorxiv.org
The aging process is characterized by a general decrease in physical functionality and poses the biggest risk factor for a variety of diseases such as cancer, cardiovascular diseases, and neurodege...
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WOW!! A new pre-print rethinking how mosquitoes, the world's deadliest animal, mates. Amazing work from Leah @LeahHouri (former PhD student in my lab) conducted in @leslievosshall's lab. Huge implications! Leah found that contrary to what was previously thought, mosquito mating
biorxiv.org
Female mosquitoes typically mate once in a lifetime1–3, making this singular mating decision critically important for the female. Yet, mosquito mating has been historically viewed as male-guided,...
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Reactivation of retrotransposable elements is associated with environmental stress and ageing https://t.co/CzjTWL3Oxf
nature.com
Nature Reviews Genetics - In this Review, Della Valle et al. discuss the role of retrotransposable elements (RTEs) in the onset and progression of ageing and ageing-related disease, including...
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That's dramatic (and cool): "archaea species can also form multicellular tissue–like structures when compressive forces are applied... ... These results establish multicellularity as a feature of all three domains of life" https://t.co/BUd2GCqaRu
science.org
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal...
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על פרסים שמתנשאים על ערבים... הייתה לנו שיחה ממש מעניינת על המון נושאים שבד"כ לא מגיעים אליהם בפודקסטים רגילים, תקשיבו! השיחה המלאה כאן: https://t.co/OXRze3uUxH
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A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival https://t.co/TuoPY6Eysy
#biorxiv_molbio
biorxiv.org
Argonautes are ancient proteins with well-characterised functions in cell-autonomous gene regulation and genome defense but less clear roles in non-cell-autonomous processes. Extracellular Argonautes...
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Check out this amazing pre-print: recodings of brain-wide dynamics reveal an hierarchical organization of behavior: "information about major actions is broadcast via a distributed manifold, to enable nesting of granular motor patterns within those major actions" @itamar_lev
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Many congratulations to Maya Voychek and co. for crafting such a fantastic preprint ( https://t.co/vvBuXRjTQJ ) and for being an outstanding community member, mentor and super mom! 1/2
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🚨Paper alert 🚨 Our latest research is out in @Nature! We reveal a surprising new role for the proteasome in innate immunity: generating antimicrobial peptides that can directly disrupt bacterial membranes. 🦠⚡ @WeizmannScience @Sys_Immunology 🔗 https://t.co/YzgdM8gsON 🧵👇
nature.com
Nature - Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics...
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We are ready to recruit new postdocs to join our team at MPI Biology Tübingen! Please help us spread the words. Thank you!!! 😊
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Excited to share our new paper in Nature! 'Transcriptomic neuron types vary topographically in function and morphology' explores how neurons in the zebrafish optic tectum exhibit diverse functions and shapes despite similar transcriptional profiles. https://t.co/289nAF8Pu3
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Almost 200 people signed up already - add your name soon before we have to stop registration for this once in a life time conference!
docs.google.com
June 10-13 in Prague & in the Woods of Bohemia Sign up here to receive information! What do we require for doing good and enjoyable science? François Jacob said it well: we need ‘an atmosphere of...
IT'S HAPPENING! The Woodstock of Biology 2.0 meets Night Science @nightsciencepod 10-13 of June in Prague & the Woods of Bohemia... Be there or be REJECTED. #theconferencetoendallconferences
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