Glad to be involved in this study on arcyriaflavin compound!

🎉Big news! Bactobio has received two awards from the Engineering Biology Collaborative R&D program, thanks to @UKRI_News & @innovateuk! 🚀 A game-changing moment for us as we aim to transform antimicrobial discovery with our cutting-edge synthetic biology. Updates to follow📰

Kia Ora Wellington! It’s been a blast these past 4 years. On to the next adventure!

Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides opens possibilities for the discovery and production of nonribosomal peptides with diverse biological activities.@nchembio https://t.co/ZGfthRkPa2

Thrilled that the 2nd AusNZ Natural Product Chemistry & Biology Symposium @SMS_UWA is starting!! First up we have Nancy Keller @TheKellerLab from University of Wisconsin-Madison on the chemistry and biology of highly interesting Isocyanide compounds from fungi.

And the Oscar goes to…. 😂

CHAP and @bactobio have collaborated to harness novel compounds from untapped soil bacteria to control foliar diseases in wheat Find out more in our brand new project video ▶️Watch the video: https://t.co/6jbzzyEjpz @Rothamsted @DefraGovUK @UKRI_News

CRISPR-containing bacteriophages are being developed by biotechs as an alternative to antibiotics. These viruses can kill harmful bacteria without damaging the healthy microbiome. Read more in my News analysis for @NatureBiotech https://t.co/CzGXpQS3m1

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent immune response against a distant tumor. @yerinchen led the charge w/ help from @DjenetBousbaine, @VeinbachsA, @BelkaidLab. @ScienceMagazine 1/26 https://t.co/bgW3C7CJgh

Can large language models understand genomic sequences and uncover new biology? 🧬🧬🧬 Excited to share a new #preprint with @sokrypton, @ancornman1, and @pgirguis. TLDR: A Large Language Model for genomic sequences! #genomics #AI #machinelearning #NLP https://t.co/g6FPz5c8bs 1/

Here are the big takeaways from the @IPCC_CH Synthesis Report released today. First, climate change has already caused widespread and substantial losses to almost every aspect of human life on this planet, and the impacts on future generations depend on the choices we make NOW.

Metabolomics is extremely hard. Why is it so different to the other ‘omics?

This looks cool in @mSystemsJ: “draft genome sequences for 322 lichen-associated actinomycetes” ▶️ “reservoirs for discovering new SMs” A Genomic Survey of the Natural Product Biosynthetic Potential of Actinomycetes Isolated from New Zealand Lichens https://t.co/WPoGAGyd4r

Interferon λ, a new way to cut hospitalizations by 50% after Covid, in a randomized, placebo-controlled trial >2,000 patients age 50+ or high risk @dr_gilmarreis and colleagues https://t.co/njkI3VzbB1

Today we're proud to announce our latest £6Mn raise to help us discover novel antimicrobials. Funds will support our mission to help turn our captured biodiversity into commercial products. ▶️Read more here: https://t.co/pa0X5vADHy #biotech #fundraise #announcement

In the LLM-science discussion, I see a common misconception that science is a thing you do and that writing about it is separate and can be automated. I’ve written over 300 scientific papers and can assure you that science writing can’t be separated from science doing. Why? 1/18

Oh how fun! The links are real but are totally unrelated papers. https://t.co/N9DMrKtYnN https://t.co/LMgvPsLymo

And when queried about the papers that could not be found, it doubled down and suggest a publisher's paywall was the reason. I wish it could just come clean and say that this is a fabricated response to look and sound right.

Was trying to look for an answer to a very specific question in NRPS biosynthesis - are there examples of NRPS BGC producing truncated peptides when expressed in heterologous hosts. And ChatGPT threw out some fabricated references that look legit to non-experts.

Related to the query above: are there examples of NRPS or PKS clusters heterologously expressed in other hosts, but only made truncated products? All examples I have seen so far were studied in native hosts. Thanks!