TheKellerLab
@TheKellerLab
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Updates from the Nancy Keller lab at University of Wisconsin-Madison. Fungal genetics, genomics, and secondary metabolism. 🍄 Managed by grad students
Madison, WI
Joined August 2020
🚨I will be hiring two postdoctoral scholars to start early 2025 at our new lab at UC Berkeley🚨 If you are attending MSA in Toronto next week and want to chat about either of these positions, please contact me! 🌱🍄 📄Details & application instructions:
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🚨job alert!🚨 An exciting opportunity to study #fungi and their secondary metabolites in the Rush lab at Oak Ridge. Please pass it along: #postdocposition
https://t.co/76MHNyNqDK
jobs.ornl.gov
Postdoctoral Research Associate - Fungal Systems Biology
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In addition to summarizing the field, we included some novel analyses that give insight into the untapped biosynthetic potential within the fumigatus species complex (hint, it's a lot). There's still much work we must do as a community!
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Our latest review summarizing every characterized BGC and their elucidated products in Aspergillus fumigatus has now been published! Open access. We hope this is a helpful resource to the fumigatus community 😁 @MDPIOpenAccess
https://t.co/nRC4fBOpMA
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New Research: Vibrio gazogenes-dependent disruption of aflatoxin biosynthesis in Aspergillus flavus: the connection with endosomal uptake and hyphal morphogenesis #microbiology
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This is a back-to-back publication with @BayramLAB which shows similar findings on the conservation of the KERS chromatin regulatory complex in Aspergillus flavus https://t.co/Xph3RxuK5T
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We are excited to share our latest paper led by @dianiluciano on the role of the histone demethylase KdmB in Penicillium expansum. Here, we show that KdmB mediates virulence and secondary metabolite production in the apple host. https://t.co/mK3F1GAD3V
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#MDTP Student Highlight: Nayanna M. Mercado-Soto @Nay_MMS is a 3rd year PhD candidate in Keller Lab (@TheKellerLab) and Huttenlocher lab studying Aspergillus fumigatus and Pseudomonas aeruginosa infections in the zebrafish larval model. #WomenInSTEM #PhDChat #UWGrad #NSFGRFP
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Exciting research being done by CMB student, Grant Nickles, and the Keller lab! @GrantNickles18
https://t.co/7P9N0aBCsm
news.wisc.edu
Researchers have trained a new algorithm based on promising new targets and reinvigorated the search for clusters of genes likely to result in interesting biological compounds.
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Curious if your fungus of interest contains any ICS BGCs? You can find out for yourself! We've created a website to host all ICS BGC predictions made in the study. Check it out at: https://t.co/QRg2qZnfrg. 🌐🔍
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📢 Exciting news! 🎉 My FIRST, first-author research paper is now available in @NAR_Open! 📚 🔗:
academic.oup.com
Abstract. The products of non-canonical isocyanide synthase (ICS) biosynthetic gene clusters (BGCs) mediate pathogenesis, microbial competition, and metal-
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Phantom #Threads – Fungal protein ZfpA protects the infection from the immune system and antifungal drugs #fungalinfection Image & research by @TJSchoen et al Huttenlocher Lab, @TheKellerLab @UWMadison in @PLOSpathogens. Read more on https://t.co/SFpJbycnAz with @MRC_LMS
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Congratulations to Nancy Keller from @UWMadisonMMI who was awarded a patent in May! Share your idea with us: https://t.co/dTO5qi12IN See the patent: https://t.co/owkRLPEWmf
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Close encounters of the microbial kind: Nancy Keller @TheKellerLab will explain how #bacteria and #fungi reside together in diverse environments. Hear more on this & other talks at our Annual Scientific Meeting. Book your place at: https://t.co/LNEf9DIdJn
#research #microbiology
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#Invasive plants and animals get all the limelight. But a deadly #mushroom is spreading east after being introduced to the US west coast. Our work opens the opportunity to explore why. https://t.co/eUWHli9Uon
news.wisc.edu
The discovery could help researchers better understand how the toxic fungus is successfully invading California and open the door for new drug discovery pathways.
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Check out our collaborative project with @JeanMichelAne, @TheKellerLab on mapping GRNs in Aspergillus and a visualization tool https://t.co/Rg0Pa8TTpy to explore our resource. Work led by outstanding trainees: Spencer Halberg-Spencer, @saptarshipyne01, Cristobal Carriel!
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Check out this podcast featuring our former lab member, Dr. Luciano-Rosario @dianiluciano !
A recent podcast featuring @dianiluciano explores the impact of storage bins in #postharvest diseases caused by #fungi! Where do your spores come from? 🍄 https://t.co/S0uEePiJLN
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What makes the 🍄☠️death cap☠️🍄 so deadly? Our paper @ISMEjournal explores the #toxin gene family of #Amanita phalloides showing differences between mushrooms, #invasive and native ranges, and revealing ancient origins Ft @TheKellerLab and Pringle Lab https://t.co/0ZoVLmZ1P1
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ASM wrote a press release on our paper. Check it out here 😁--> https://t.co/Fobm8qj4BA
asm.org
In a new study, researchers use cheese rinds to demonstrate that fungal antibiotics can influence how microbiomes develop.
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In our latest study, we shed light on a fascinating group of specialized metabolites secreted by Penicillium species. These compounds play a crucial role in regulating the development of cheese rinds 🧀 by selectively inhibiting specific bacterial community members 🦠.
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