The Hsieh-Wilson Lab
@hsiehwilson_lab
Followers
579
Following
876
Media
24
Statuses
103
Student-run twitter account for the Hsieh-Wilson lab @Caltech @CaltechCCE. Chemistry, neurobiology, #glycotime!
Pasadena, CA
Joined July 2020
Check out our latest paper in @PNASNews on the role of glycosaminoglycan sulfation patterns in regulating synapses, perineuronal nets, and social memory! For an overview, see the QnA article with @Lhsiehwilson. Congratulations to Tracy and coworkers! 👏 https://t.co/fmGtuJLrzz
pnas.org
Glycan alterations are associated with aging, neuropsychiatric, and neurodegenerative diseases, although the contributions of specific glycan struc...
1
14
29
Chemoenzymatic Labeling, Detection and Profiling of Core Fucosylation in Live Cells | Journal of the American Chemical Society @Caltech @CaltechCCE #Chemoenzymatic #Labeling #Detection #Profiling #Fucosylation #Live #Cells
pubs.acs.org
Core fucosylation, the attachment of an α-1,6-linked-fucose to the N-glycan core pentasaccharide, is an abundant protein modification that plays critical roles in various biological processes such as...
0
6
14
In @J_A_C_S: a new chemoenzymatic labeling method for α-1,6-linked fucose (core fucose), with ELISA integration for detecting cancer-related biomarkers in patient serum samples. Congrats to @JeanLucChaubard, Qiang Zhu, & team!
pubs.acs.org
Core fucosylation, the attachment of an α-1,6-linked-fucose to the N-glycan core pentasaccharide, is an abundant protein modification that plays critical roles in various biological processes such as...
0
3
26
New paper from @hsiehwilson_lab and others on a new approach to label core a1,6-Fuc - using Caenorhabditis GALT-1 - I'm acknowledged as years ago we sent some fucosylated glycopeptide substrate. #glycotime
https://t.co/uyiWYB4HQv
pubs.acs.org
Core fucosylation, the attachment of an α-1,6-linked-fucose to the N-glycan core pentasaccharide, is an abundant protein modification that plays critical roles in various biological processes such as...
0
7
31
What an honor to join such an inspiring group of scientists. I am tremendously grateful to the @BeckmanFnd for funding this project and to the @MGriffinLab for their fearless work. We're excited to continue pushing the boundaries of #glycotime, so...
Congratulations to 2024 Beckman Young Investigator Awardee Matthew Griffin, PhD! https://t.co/9kUBF1pjwo
#byi @ucirvine
5
3
22
Phenomenal seminar today @CornellChem by @Lhsiehwilson @CaltechCCE — from powerful new synthetic methods (go fluorous phase!) to mouse studies of social behavior to understand the sulfation code of glycosaminoglycans! #glycotime
0
2
27
Sugar doesn’t just help the medicine go down; sugar can be the medicine. @michiganstateu @Xuefei_lab is part of a national team uncovering how carbohydrates could pioneer new treatments, from battling cancer to taming autoimmune disorders. More: https://t.co/IKUEVLxzg3
1
6
22
New paper on aSyn O-GlcNAc modification with @Hlashuel and amazing collabs. @SaelicesL, Kelvin Luk & Virginia Lee. Briefly, we find that a certain O-GlcNAc forces aSyn to make a distinct amyloid structure which can seed aggregation in vitro but…
1
11
40
Congratulations to Professor Shu-ou Shan @Caltech / @CaltechCCE winner of the 2024 @theNASciences Award in Molecular Biology, for her novel research on molecular mechanisms underlying critical cellular processes! #NASaward #MolecularBiology
0
3
26
That being said, we're hiring at all levels (undergrads, Ph.D. trainees, and postdocs)! Check out our open positions to tackle bioinformatic enzyme discovery, microbial engineering, and cancer immunology at https://t.co/nM30gPMicM. (Please disseminate widely!)
0
17
14
A great time at today's Chemical Biology & Molecular Biosciences (CB&MB) social! The social, which followed a scavenger hunt for new students through the labs, kicked off the first year of the new CB&MB track within the chemistry grad program. https://t.co/dRNBkIm1ny
0
0
6
Congratulations to Hsieh-Wilson lab alum, and assistant professor of chemistry at @UCIChemistry, @Matt_E_Griffin on being awarded the V Scholar Research Grant! https://t.co/xVE6fhfdCz 🧪👏
ps.uci.edu
The award honors interdisciplinary work to understand the human microbiome.
1
0
11
@Lhsiehwilson now moves onto #chondroitin sulphates and their roles in perineuronal nets & neuroplasticity, including social memory.
0
1
6
@Lhsiehwilson shows at #glyco26 how her lab exploits a unique set of 64 ‘printable’ #heparan sulphate tetrasaccharides. Now able to test the FGF family’s ability to recognize different sulphation states.
1
1
5
📢NOW HIRING: The Division invites applications for a faculty position at all levels with research interests in chemical biology and all areas of chemistry, including inorganic, organic, physical, theoretical, and materials chemistry. APPLY➡️: https://t.co/vVoFjesXRt
0
5
15
The Tetrahedron Prize Symposium is in room 7 at #ACSFall2023 Great talks so far from both Linda Hsieh Wilson @Lhsiehwilson @hsiehwilson_lab and Eric Jacobsen @JacobsenLab celebrating our winner Chi-Huey Wong
1
4
17
Linda Hsieh-Wilson and team found that sugar molecules are important for the communication between nerve cells. These finding could have implications for repairing neurons after injury. Watch the full briefing from #ACSFall2023: https://t.co/Ilor098ynn
0
3
6
Complex sugars called glycosaminoglycans affect “plasticity” in the brains of mice, according to research being presented today at #ACSFall2023, which could help us understand how memory and learning work in humans. https://t.co/1HmvzF5xpY
@hsiehwilson_lab @CaltechCCE @Caltech
0
3
8
Congrats @clemonslab @profbilc!
We are absolutely thrilled to finally share our new structure from @clemonslab of escape mechanism of the smallest phages (φX174) by breaching the peptidoglycan layer, now out in Science! https://t.co/haFGabV5eE 🧵 In this thread, I'll give you a sneak peek of the YES complex👇🏼
0
0
5