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Alex Melamed Profile
Alex Melamed

@headofmelon

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Gynecologic Oncology practice @MassGenNews. Researching how real-world cancer care affects real-world patients. He/his/him/himself

Joined March 2013
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@headofmelon
Alex Melamed
3 months
Our latest lead by Dr. Katy Abel. More evidence that underutilization of NACT is associated with worse post-operative outcomes, without any hint of long-term benefit, even in high-volume centers.
@JAMANetworkOpen
JAMA Network Open
4 months
For patients with advanced-stage ovarian cancer, higher utilization of neoadjuvant chemotherapy at high-volume centers was associated with the lowest 90-day surgical mortality and longest 60-month survival. https://t.co/NvOIMK7ZET
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@nagustiga
Núria Agustí Garcia
5 months
Our JAMA Oncology study is now featured in the @IJGConline podcast! Thank you for highlighting our work. Grateful to work with such an amazing team! @dviverosc @headofmelon @NiteckiRoni @RParejaGineOnco @RauhHainMD
@IJGConline
IJGC
5 months
🎙️ New #IJGCConversations Episode! 🚨 Radiation alone vs. Chemoradiation in Intermediate Risk #CervicalCancer with @nagustiga and @dviverosc 🎧 Tune in now and stay ahead in #GynOnc! 🔗 https://t.co/YP7ULOejCm @pedroramirezMD @HsuMd @JayrajAarthi @AndreFernandes2 @IGCSociety
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@headofmelon
Alex Melamed
10 months
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@nagustiga
Núria Agustí Garcia
10 months
Our 15-year cohort study explores trends in surgical de-escalation in gynecologic oncology. These findings are transforming patient care but raise important questions about the preparation of fellows in surgical training. @headofmelon @dviverosc @RauhHainMD @NiteckiRoni
@JAMANetworkOpen
JAMA Network Open
10 months
Gynecologic oncology is moving towards less invasive surgical methods and decreased surgery overall, which likely benefits patients but also raises challenges for surgical training and the equitable access. https://t.co/5ToUXj8xIv
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@headofmelon
Alex Melamed
1 year
LANCE trial lead-in pilot shows the feasibility of a phase III study to evaluate the efficacy of MIS for interval cytoreduction in ovarian cancer. @RauhHainMD @annafagottimd @RParejaGineOnco @pedroramirezMD @abedsinno
@JAMANetworkOpen
JAMA Network Open
1 year
LANCE RCT: A minimally invasive surgery for advanced ovarian cancer after neoadjuvant chemotherapy is feasible and may reduce postoperative complications compared to laparotomy. https://t.co/ZfEn4aamYF
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@NiteckiRoni
Roni Nitecki Wilke
1 year
#cancer during #pregnancy is associated with severe maternal and neonatal morbidity. Proud of the entire team for this important manuscript! https://t.co/qB7QRETVkK @RauhHainMD @headofmelon @markaclapp @abigailflynt @dviverosc @nagustiga @MDAndersonNews @AJOG_thegray
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@headofmelon
Alex Melamed
1 year
What an honor for us to host @scambiagiovanni and @annafagottimd at @MghObgyn.
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@headofmelon
Alex Melamed
1 year
Cool picture of a adenosarcoma assocaited uterine inversion which we treated laparoscopically. Nice work by Baran Vardar and @AlexBercowMD getting these pictures into the literature. https://t.co/D6Yy7Erjpp
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@headofmelon
Alex Melamed
1 year
Josseli Barnica is the victim of a totalitarian state imposing its ideology on women’s bodies. America we are better than this.
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@headofmelon
Alex Melamed
1 year
NACT and interval cytoreductive surgery edges out primary cytoreductive surgery as the most frequent treatment for advanced-stage ovarian cancer in the US. 11 years after Vergote et al. It really does take a decade.
@JAMANetworkOpen
JAMA Network Open
1 year
Since 2021, neoadjuvant chemotherapy followed by interval cytoreductive surgery has become the most prevalent approach of upfront treatment for patients with advanced epithelial ovarian cancer in the US.
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@JAMANetworkOpen
JAMA Network Open
1 year
Since 2021, neoadjuvant chemotherapy followed by interval cytoreductive surgery has become the most prevalent approach of upfront treatment for patients with advanced epithelial ovarian cancer in the US.
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@headofmelon
Alex Melamed
1 year
Thanks @IJGConline and @pedroramirezMD for this great honor.
@IJGConline
IJGC
1 year
📣 Great news!!! Dr. Alexander Melamed joins the #IJGC #AssociateEditors team 🔥 🔥 Welcome Alex!🤩 @pedroramirezMD @HsuMd @JayrajAarthi @AndreFernandes2 @IGCSociety @ESGO_society @ENYGO_official @OncoAlert @IJGCfellows @GynMe4
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@headofmelon
Alex Melamed
2 years
A new paper by super intern Katy Abel looks at the use and efficacy of primary site surgery in metastatic cancer. There is a lot of heterogeneity across cancer sites, raising essential questions about how, and if, we know when surgery is helpful https://t.co/DRXYL9mUcp
Tweet card summary image
onlinelibrary.wiley.com
Purpose To assess the impact of primary-site surgery plus systemic therapy compared to systemic therapy alone on overall survival in common metastatic cancer types. Methods Data sources included E...
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@headofmelon
Alex Melamed
2 years
A new paper by Jason Silberman @JSilby3: who is on the market for the gyn onc fellowship spot! https://t.co/96GXOnqXyW cytotoxic NACT has increased for stage III&IV low-grade serous ovarian cancer in last 15y w/o evidence that this approach is effective in this cancer type
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@headofmelon
Alex Melamed
3 years
Nice study from Vrede et al: The molecular subtype may not be prognostically important for low-grade endometrioid endometrial cancer Relevance of Molecular Profiling in Patients With Low-Grade Endometrial Cancer https://t.co/uGKtQQS9lz via @JAMANetworkOpen part of @JAMANetwork
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@AbbasHassanMD
Abbas M. Hassan, MD, PhD
3 years
Our latest study in @JAMASurgery revealed that spending for cancer surgery decreased significantly among Medicare beneficiaries. Read the full text: https://t.co/u3sniF1G6G @headofmelon @NancyKeatingMD @anaeze_offodile
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@emollick
Ethan Mollick
3 years
If you last checked in on AI image makers a month ago & thought “that is a fun toy, but is far from useful…” Well, in just the last week or so two of the major AI systems updated. You can now generate a solid image in one try. For example, “otter on a plane using wifi” 1st try:
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@headofmelon
Alex Melamed
3 years
The dramatic difference between leg room one gets in economy compared to economy plus seems like an ominous symptom of declining solidarity in US society. But also: I’m never flying regular economy again.
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@headofmelon
Alex Melamed
3 years
When you ask the intern for the patient’s oncologic history on rounds:
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