Alex Melamed
@headofmelon
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Gynecologic Oncology practice @MassGenNews. Researching how real-world cancer care affects real-world patients. He/his/him/himself
Joined March 2013
Our latest lead by Dr. Katy Abel. More evidence that underutilization of NACT is associated with worse post-operative outcomes, without any hint of long-term benefit, even in high-volume centers.
For patients with advanced-stage ovarian cancer, higher utilization of neoadjuvant chemotherapy at high-volume centers was associated with the lowest 90-day surgical mortality and longest 60-month survival. https://t.co/NvOIMK7ZET
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Our JAMA Oncology study is now featured in the @IJGConline podcast! Thank you for highlighting our work. Grateful to work with such an amazing team! @dviverosc @headofmelon @NiteckiRoni @RParejaGineOnco @RauhHainMD
🎙️ New #IJGCConversations Episode! 🚨 Radiation alone vs. Chemoradiation in Intermediate Risk #CervicalCancer with @nagustiga and @dviverosc 🎧 Tune in now and stay ahead in #GynOnc! 🔗 https://t.co/YP7ULOejCm
@pedroramirezMD @HsuMd @JayrajAarthi @AndreFernandes2 @IGCSociety
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Our 15-year cohort study explores trends in surgical de-escalation in gynecologic oncology. These findings are transforming patient care but raise important questions about the preparation of fellows in surgical training. @headofmelon @dviverosc @RauhHainMD @NiteckiRoni
Gynecologic oncology is moving towards less invasive surgical methods and decreased surgery overall, which likely benefits patients but also raises challenges for surgical training and the equitable access. https://t.co/5ToUXj8xIv
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LANCE trial lead-in pilot shows the feasibility of a phase III study to evaluate the efficacy of MIS for interval cytoreduction in ovarian cancer. @RauhHainMD @annafagottimd @RParejaGineOnco @pedroramirezMD @abedsinno
LANCE RCT: A minimally invasive surgery for advanced ovarian cancer after neoadjuvant chemotherapy is feasible and may reduce postoperative complications compared to laparotomy. https://t.co/ZfEn4aamYF
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#cancer during #pregnancy is associated with severe maternal and neonatal morbidity. Proud of the entire team for this important manuscript! https://t.co/qB7QRETVkK
@RauhHainMD @headofmelon @markaclapp @abigailflynt @dviverosc @nagustiga @MDAndersonNews @AJOG_thegray
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Cool picture of a adenosarcoma assocaited uterine inversion which we treated laparoscopically. Nice work by Baran Vardar and @AlexBercowMD getting these pictures into the literature. https://t.co/D6Yy7Erjpp
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Josseli Barnica is the victim of a totalitarian state imposing its ideology on women’s bodies. America we are better than this.
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NACT and interval cytoreductive surgery edges out primary cytoreductive surgery as the most frequent treatment for advanced-stage ovarian cancer in the US. 11 years after Vergote et al. It really does take a decade.
Since 2021, neoadjuvant chemotherapy followed by interval cytoreductive surgery has become the most prevalent approach of upfront treatment for patients with advanced epithelial ovarian cancer in the US.
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Since 2021, neoadjuvant chemotherapy followed by interval cytoreductive surgery has become the most prevalent approach of upfront treatment for patients with advanced epithelial ovarian cancer in the US.
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Thanks @IJGConline and @pedroramirezMD for this great honor.
📣 Great news!!! Dr. Alexander Melamed joins the #IJGC #AssociateEditors team 🔥 🔥 Welcome Alex!🤩 @pedroramirezMD @HsuMd @JayrajAarthi @AndreFernandes2 @IGCSociety @ESGO_society @ENYGO_official @OncoAlert @IJGCfellows @GynMe4
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A new paper by super intern Katy Abel looks at the use and efficacy of primary site surgery in metastatic cancer. There is a lot of heterogeneity across cancer sites, raising essential questions about how, and if, we know when surgery is helpful https://t.co/DRXYL9mUcp
onlinelibrary.wiley.com
Purpose To assess the impact of primary-site surgery plus systemic therapy compared to systemic therapy alone on overall survival in common metastatic cancer types. Methods Data sources included E...
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A new paper by Jason Silberman @JSilby3: who is on the market for the gyn onc fellowship spot! https://t.co/96GXOnqXyW cytotoxic NACT has increased for stage III&IV low-grade serous ovarian cancer in last 15y w/o evidence that this approach is effective in this cancer type
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Nice study from Vrede et al: The molecular subtype may not be prognostically important for low-grade endometrioid endometrial cancer Relevance of Molecular Profiling in Patients With Low-Grade Endometrial Cancer https://t.co/uGKtQQS9lz via @JAMANetworkOpen part of @JAMANetwork
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Our latest study in @JAMASurgery revealed that spending for cancer surgery decreased significantly among Medicare beneficiaries. Read the full text: https://t.co/u3sniF1G6G
@headofmelon @NancyKeatingMD @anaeze_offodile
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If you last checked in on AI image makers a month ago & thought “that is a fun toy, but is far from useful…” Well, in just the last week or so two of the major AI systems updated. You can now generate a solid image in one try. For example, “otter on a plane using wifi” 1st try:
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The dramatic difference between leg room one gets in economy compared to economy plus seems like an ominous symptom of declining solidarity in US society. But also: I’m never flying regular economy again.
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When you ask the intern for the patient’s oncologic history on rounds:
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