Computational Transcriptomics
@goekelab
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Lab of Computational Transcriptomics @astar_gis. Software releases, publications, journal clubs, anything long read RNA-Seq by team members. PI @jonathangoeke
Singapore
Joined March 2021
RT @astar_gis: 🚀 Exciting News from Singapore! 🚀. Scientists at A*STAR's Genome Institute of Singapore (@astar_gis) have unveiled one of th….
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RT @naturemethods: This Analysis presents benchmarking results from the Singapore Nanopore Expression consortium project, including a valua….
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For the new release of SG-NEx v0.6.0, it now features updated fastq/bam files processed with Guppy 6.4.2 & Minimap2-2.22. Check out here for more details on the resource:
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The project is a close collaboration with experts from multiple institutions, including @Hasindu2008, @aka_hpatel, @AliciaOshlack, @mikelove, and many others. We are grateful for their support and contributions to this study.
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The SG-NEx data is a comprehensive resource for enabling the development and benchmarking of computational methods for profiling complex transcriptional events at isoform-level resolution.
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The manuscript provides a systematic benchmark of long-read and short-read RNA-seq protocols, demonstrates the value of long-read RNA-seq data in understanding alternative isoforms, novel transcripts, fusion transcripts and m6A RNA modifications.
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We are happy to share that our SG-NEx manuscript (led by @chenying927, @nadia_davidson, @yukkeiwan and @JonathanGoeke), is now out with open access: together with an update release of SG-NEx data v0.6.0!
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RT @shyam_lab: Great to see this software tool that enables long-read single cell and spatial transcriptomics!.
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RT @astar_gis: Congratulations to our Bambu team: @JonathanGoeke, Andre Sim, Min Hao Ling, Ying Chen, Sui Yue, and @JayShin on the release….
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RT @JonathanGoeke: The recommended way to run bambu-clump is through the nextflow pipeline (bambu-pipe), which optimises barcode detection,….
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RT @JonathanGoeke: Very happy to release the single cell and spatial long read RNA seq module for our transcript discovery and quantificati….
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RT @biorxiv_bioinfo: Isoform-level discovery, quantification and fusion analysis from single-cell and spatial long-read RNA-seq data with B….
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RT @CellCellPress: Now online! An atlas of transcription initiation reveals regulatory principles of gene and transposable element express….
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RT @astar_gis: Congratulations @JonathanGoeke @J_i_n_g_m_e_i from @astar_gis, recipients of the 2024 A*STAR Fellows for their outstanding c….
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RT @astar_research: Meet the latest recipient of the Young Scientist Award: @JonathanGoeke, Senior Principal Scientist at @astar_gis! 🏅. Gö….
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RT @astar_gis: Congratulations to @JonathanGoeke on achieving the Young Scientist Award, which recognizes young researchers who are activel….
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RT @JonathanGoeke: Many thank to my team members and collaborators, without them this would not have been possible!.
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RT @astar_research: The brainchild of researchers at @astar_gis, Bambu can detect both known and previously unidentified gene patterns with….
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RT @astar_gis: This week, we celebrate with our GIS colleagues who were conferred various awards for their distinguished service and signif….
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RT @astar_gis: @JonathanGoeke, Andre Sim and Ying Chen from @astar_gis introduced a new context-aware transcript quantification approach ca….
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