Giuseppe Biondi-Zoccai
@gbiondizoccai
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Cardiologist, scientist & former airborne officer
Rome, Italy
Joined April 2010
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You can't come to Athens for the upcoming ESC Preventive Cardiology 2024 congress on 25-27 April and miss a visit to the Parthenon! This is me today with my dearest Giuseppe Jr on top of the Acropolis
#ESCPrev2024
#cardiotwitter
#CVD
#CVPrev
#cvprevention
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20 years of uninterrupted applauses to Alain Cribier for inventing this lifesaving procedure!
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Must-read review in the latest issue of JAMA on 'Diagnosis and Treatment of Acute Myocarditis'
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Must-read review on 'Perioperative Management of Anticoagulant and Antiplatelet Therapy'
@NEJMEvidence
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Must-read: Joint British Societies’ position statement on bullying, harassment and discrimination in cardiology
@Heart_BMJ
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HF patients with ICDs on carvedilol treatment experience a significantly lower risk of atrial tachyarrhythmia and inappropriate ICD shocks when compared to treatment with metoprolol
@JACCJournals
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Cardiovascular meta-analyses: fool’s gold or gold for fools? by Giuseppe Biondi-Zoccai, Stephan Windecker, Peter Juni, Deepak L Bhatt (open access)
@ehj_ed
@DLBHATTMD
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William C. Roberts is stepping down after 40 years, Subhash Banerjee has become the new Editor-in-Chief of The American Journal of Cardiology
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Who would have thought that going to the gym would teach me the basics of the normal distribution?
(courtesy of )
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Still we miss the elephant in the room... all-cause deaths... just look at what happened in Northern Italy... this discrepancy between official COVID-19 deaths and true COVID-19 burden in mortality is the most likely explanation of the way too rosy situation in China
Important chart, as most similar analyses have not normalized the number of cases and deaths for the size of the underlying population. Note the radical differences in the top and bottom graphs. Epidemiology 101.
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Wellens syndrome followed by giant R-wave syndrome + macroscopic T-wave alternans -> LAD culprit!
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Coronary physiology in the catheterisation laboratory: an A to Z practical guide
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Another meta-analysis on novel oral anticoagulants for left ventricular thrombus: when enough is enough? by Martino, Bernardi, Pingitore et al
@JCardioMedicine
@MarcoBernardiMD
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Welcome to the '“Reverse Spider View” for left stem coronary artery angiographic evaluation', courtesy of Rigatelli et al
@ccijournal
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'Clopidogrel monotherapy after 1-month DAPT compared with 12-month DAPT reduced major bleeding events without an increase in cardiovascular events regardless of diabetes'
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Must-read review on "Acute Decompensated Heart Failure in the Setting of Acute Coronary Syndrome"
@JACCJournals
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A rosy representation of scientific publishing
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Must-read review on antithrombotic therapy for primary and secondary prevention of ischemic stroke
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In patients with angina with nonobstructive coronary arteries, ischemia on ECG stress testing (EST) was highly specific of underlying ischemic substrate. These findings challenge the traditional belief that EST has a high false positive rate
@JACCJournals
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Is there any better way to celebrate your 48th birthday than enjoying the best Amatriciana ever in the world-class La Zingarella restaurant in Rome, Italy?
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Must-read review on 'Diagnosis and Management of Prediabetes' in the latest issue of JAMA
@JAMA_current
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Must-read JACC Scientific Statement on 'Heart Failure With Preserved Ejection Fraction'
@JACCJournals
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Today a fellow told me complex CAD with ⬇️LVEF is a contraindication for CABG:
I was amazed by how poorly we are training our younger colleagues!
It's always useful to remember that the benefits of CABG go beyond the amelioration of the culprit lesion
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My ECFMG Certificate, issued on January 18, 2003 - valid indefinitely: I will never forgive me for not having moved to the US! Indeed, I had even matched at Baylor in Houston...
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'Acute coronary occlusions were found in 20% of out-of-hospital cardiac arrest patients without STEMI. The frequency of these occlusions did not differ between stable and unstable patients, and the occlusions were associated with a higher risk of death'
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A few days ago a patient of ours required a partial forearm fasciotomy after transradial PCI for a hematoma compressing the radial nerve!
It was the first case I saw with my eyes in my practice.
Have you ever seen it in your own practice?
(the picture is from the web)
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Isn't this a beauty? I just asked to DALL·E 3 from OpenAI to create the image of a heart all composed by stents of different features (eg size, length, strut shape and thickness): really amazing!
#chatgpt_at_a_glance
#CAAG
#ChatGPT
@OpenAI
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Claudio Rapezzi has passed away... A giant of international cardiology, but above all a caring colleague... He defended me from many false accusations in the Modena criminal court... And when I asked him how much I owed him, he replied "a coffee"... We will miss you Claudio!
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'Coronary microcirculatory dysfunction is frequent in patients with CAD and correlates with cerebral small vessel disease, abnormal cerebral flow haemodynamics, and significant cognitive impairment'
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Must-read review in the latest issue of The Lancet on mechanisms and management of valvular heart disease
@TheLancet
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Must-read review in the latest issue of JAMA on the diagnosis and management of paroxysmal supraventricular tachycardia
@JAMA_current
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Proposed optimal location of septal crossing:
-> Red: LVAD/MV implantation
-> Green: LAA closure
-> Yellow: PFO closure
-> Blue: PV intervention
-> Purple: Paravalvular leak closure/MitraClip
(from Katsiampoura et al: )
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Diagnosis and management of heart failure from hospital admission to discharge: A practical expert guidance by
@SABOURETCardio
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#FullPhysiology
: a systematic step-by-step guide to implement intracoronary physiology in daily practice, by Scarsini et al
#MinervaCardiologyAngiology
@GianlucaCampo78
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It's official! The impact factor (IF) of
#MinervaCardiologyAngiology
has nearly doubled in comparison to the previous year: from 0.713 for 2019 IF to 1.347 for 2020 IF!
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Must-read systematic review on aortic stenosis progression
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Anaphylaxis after 1st dose of the Pfizer-BioNTech COVID-19 vaccine: as few as 11 cases reported in VAERS per 10,000,000 doses administered, without any death
via
@JAMA_current
part of
@JAMANetwork
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I have finally reached the milestone of 1,000 entries in MEDLINE/PubMed, between 2000 and 2023: many thanks to all my mentors, colleagues and mentees who have supported me over these 23 years of scholarly publishing!
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Management strategies for heavily calcified coronary stenoses: an EAPCI clinical consensus statement in collaboration with the EURO4C-PCR group
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We are proud to announce that the Impact Factor of Minerva Cardiology Angiology has nearly doubled in 1 year: it is now 2.269!
Many thanks to all our readers, authors, and editorial board members!
#MinervaCardiologyAngiology
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According to a 22,586-patient Canadian registry, comparing CABG vs PCI for left main disease, 'after matching, there was no difference in early mortality but improved late survival and freedom from MACCE with CABG'
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Reverse-TAP: the new kid on the block for coronary bifurcation stenting (basically a blend of crush and SKS?)
@BifurcationClub
@BURZOTTA_F
@tmuenzel
@SVRaoMD
@mmamas1973
@LAzzaliniMD
@GoranEBC
@sbrugaletta
@MarioIannaccon8
@GianlucaCampo78
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Revascularization strategies versus optimal medical therapy in chronic coronary syndrome: A network meta-analysis, by Galli et al
@MattiaGalli10
@DFCapodanno
@DDamario
@ItaloPorto2
@BURZOTTA_F
@JEscaned
@ehj_ed
@IJCardio
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Direct oral anticoagulants versus vitamin K antagonists in the treatment of left ventricular thrombosis: when off label becomes routine, by Di Muro et al
#MinervaCardiologyAngiology
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Really sad to read today the landmark editorial on the COAPT score from the late Michele Pighi: we will miss you!
@JACCJournals
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De-escalation of antiplatelet therapy in patients with coronary artery disease: Time to change our strategy? by Sabouret et al
@SABOURETCardio
@LuigiSpadafora
@DrMarthaGulati
@SaDeRosa78
@DocSavageTJU
@MattiaGalli10
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For those passionate about statistics, I have created 2 TikTok channels, 1 in English, and 1 in Italian, naming them "Statistics in 15 Seconds": the main strength is I try to explain key statistical concepts in understable terms and in </= 15 seconds
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According to a comprehensive network meta-analysis including 24 RCTs and 6,890 patients, a double kissing crush technique is clearly the best option for true coronary bifurcation lesions!
@DFCapodanno
@EuroInterventio
@sbrugaletta
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Must-read review on "diagnosis and treatment of acute coronary syndromes", by Bhatt, Lopes and Harrington
@JAMA_current
@DLBHATTMD
@HeartBobH
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A must-reply question for any would-be invasive cardiologist: who are these three guys?
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Radial artery avulsion due to irreversible spasm: have you ever had a similar case?
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We have just submitted the final draft of our handbook entitled 'ChatGPT for Medical Research', which will be published soon by Edizioni Minerva Medica: we dearly hope you will find it interesting and useful when finally available in print!
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Today I have finally reached 💯 on Google Scholar: many thanks for all the people smarter than me I have had the privilege to collaborate with!
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Must-read review on management of adults with anomalous aortic origin of the coronary arteries, by Gaudino et al
@JACCJournals
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Lucky me! I have just been informed that I have been inducted in the Editorial Board of the prestigious American Journal of Medicine
@amjmed
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4 high-risk plaque features on coronary CT angiography were associated with features of vulnerability on invasive OCT: positive remodeling, low-attenuation plaque, napkin-ring sign, and spotty calcification
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Must-read review from Eugene Braunwald on "Gliflozins in the Management of Cardiovascular Disease" in The New England Journal of Medicine
@NEJM
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'Modified TAP stenting (pulling the SB stent before inflating it until it indents a 4 ATM-inflated MB balloon) resulted in larger stent area and shorter neocarina than TAP stenting in bench testing'
@ccijournal
@BURZOTTA_F
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"Head-Up Tilt Table (HUTT) in post-acute sequela of COVID-19 (PASC) patients revealed orthostatic intolerance suggestive of autonomic dysfunction in nearly all subjects"
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A meta-analysis including 12 studies and 8,377 patients suggests that "provisional stenting should be the preferred technique over dual stenting when treating left main bifurcation lesions with DES"
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Another proof that impact factor (IF) has a very limited association with quality and impact... Statistics in Medicine, a key resources for all biomedical and clinical researchers, has a modest 2.5... Still, every issue is worth perusing in detail!
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Kudos to Simone Biscaglia for being the recipient of the TCT Linnemeier Young Investigator Award thanks to his many achievements, including the landmark FIRE trial
#TCT2023
@SimoneBiscaglia
@TCTMD
@crfheart
@GianlucaCampo78
@SMTStents
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The guide extension tunnel in landslide technique (TILT) for equipment delivery in severely tortuous or uncrossable lesions during percutaneous coronary intervention
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Must-read systematic review on complete percutaneous coronary revascularization in acute coronary syndromes with multivessel coronary disease
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"Transradial access was noninferior to transfemoral access for CTO PCI but had fewer access-site complications"
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The career of Christian Eriksen has likely ended yesterday... but what troubles me most is the ineffectiveness of screening tests, even in professional athletes
#ChristianEriksen
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Must-read review on 'Pathophysiology, Echocardiographic Diagnosis, and Treatment of Atrial Functional Mitral Regurgitation'
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'Classification of edge-to-edge mitral valve repair patients into HFrEF-secondary mitral regurgitation stages according to extramitral cardiac involvement provides prognostic value in terms of postinterventional survival and symptomatic improvement'
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Must-read review on state-of-the-art management of stable ischemic heart disease
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Have you ever placed 2 sheaths in the same radial artery? A few days ago we did it! Eventually it proved successful and uneventful!
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In the DanGer Shock randomized trial, including 360 patients with STEMI complicated by cardiogenic shock, Impella reduced 180-day all-cause death from 59% to 46% (p=0.04, NNT=8), and a composite endpoint of escalation of treatment to additional MCS, heart transplantation, or…
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'Patients with thrombotic antiphospholipid syndrome randomized to DOACs compared with VKAs appear to have increased risk for arterial thrombosis. No significant differences were observed for subsequent VTE or major bleeding'
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Must-read state-of-the-art review on major global coronary artery calcium guidelines, concluding that knowing them 'is essential for clinicians to correctly adjudicate personalized statin and aspirin therapy and further medical management'
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How to write an umbrella review? A step-by-step tutorial with tips and tricks
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"Improving PCI Outcomes Using Postprocedural Physiology and Intravascular Imaging": a must-read review
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How to perform ultrasound-guided pericardiocentesis without X-rays: A problem-solving step by step tutorial
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An achievement I am very proud of... thanks to
@TomLuscher
and
@ehj_ed
for their leadership and mentoring!
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Must-read JAMA Guide to Statistics and Methods article: Adjustment for Baseline Characteristics in Randomized Clinical Trials
See also
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In STEMI patients, there is a direct relationship between total stent length implanted in the culprit vessel and the risk of TLF at 10 years, mainly driven by TLR. The use of DES did not modify this association
@AmericanHeartJ
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I'll tell you a secret: I will apply!
📢 We're seeking a proven physician scientist, inspirational leader & strategic thinker to serve as the next Editor-in-Chief of
#JACC
, beginning Jan. 2024.
If you're interested, submit your application by Sept. 12 here:
#CardioTwitter
#CardioEd
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LAD is associated with a lower post-PCI FFR than non-LAD arteries, emphasizing the importance of interpreting post-PCI FFR on a vessel-specific basis
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We are all close to Michele Pighi's family for their loss... Michele will never be forgotten!
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Acute coronary syndrome stratification: is it time to go beyond the ECG? by Bernardi, Spadafora, Gaudio et al
@MarcoBernardiMD
@LuigiSpadafora
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Must-read review on "Transcatheter Aortic Valve Replacement in Failed Transcatheter Bioprosthetic Valves" by
@G_Tarantini01
et al
@JACCJournals
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'Clopidogrel monotherapy was associated with lower rate of primary composite endpoint compared to aspirin monotherapy as long-term maintenance therapy after dual antiplatelet therapy for coronary stenting in both patients with and without diabetes'
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Kudos to Francesco Saia for receiving absolute majority of votes to become a member of Board of Directors (and likely upcoming President) of Italian Society of Invasive Cardiology, with 426 votes out of the total 843 eligible (50.5%)
@saia_francesco
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A 48-year-old man with prior smoking history presents with ongoing crushing chest pain which began 1 hour before. Would you send him to the cath lab?
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Heart Failure After ST-Elevation Myocardial Infarction: Beyond Left Ventricular Adverse Remodeling, by Del Buono et al
@MarcoDelBuono3
@ISeropianMD
@thiele_holger
@AbbateAntonio
@chiarabd
@ehj_ed
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Modified TAP techinique based on pulling the side branch stent indenting the main branch balloon before inflating the former: is it a meaningful improvement for PCI of coronary bifurcation lesions?
@ccijournal
@BURZOTTA_F
@enromagnoli
@sbrugaletta
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Four AI-generated hearts courtesy of Lefteris Teperikidis... which one do you like better?
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