eBIC Beamline
@eBIC_Diamond
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eBIC provides scientists with state-of-the-art experimental equipment and expertise in the field of cryo-electron microscopy. @DiamondLightSou
Joined March 2022
📢 We’re hiring! Excellent opportunity at group-leader level for a Principal EM Scientist to underpin and further develop the electron Bio-Imaging Centre (eBIC) at Diamond Light Source as a leading centre for cryoEM. Apply by 5th October 2025 👉 https://t.co/ZlMTogLKrI
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Nice time contributing to the WTS-MRC #cryoEM ❄️🔬,training course held at @UniversityLeeds, @AstburyCentre with facilities from @SCMICryoEM, @eBIC_Diamond, @uniofleicester. Representing @ismb_london 🦉. 4x #Krios' in action 🇬🇧🌍 w/ users from across the map🗺️.
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Our method paper for HIV-1 nuclear import is out now in EMBO reports! Check it out here: https://t.co/jVZA7Z2CFJ
@GroupZhang @shen_yao10 @OxfordStrubi @NDMOxford @eBIC_Diamond @DiamondLightSou @emboreports
embopress.org
imageimageAn in situ system that recapitulates HIV-1 nuclear import using isolated HIV-1 cores and permeabilized CD4 + T cells is combined with cryo-electron tomography, enabling high-throughput...
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So excited to share our new work of in-cell Rubisco, now published in Nature Communications, check it out! https://t.co/JlRqZXVEAY
@GroupZhang @Nadav_Elad @eBIC_Diamond @OxfordStrubi @NDMOxford @WeizmannScience @NatureComms
nature.com
Nature Communications - Rubisco is a central enzyme in the global CO2 fixation during photosynthesis. Using cryo-ET on cryo-FIB milled alga cells, the authors reveal the native structures,...
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🔬 New to cryo-ET & FIB milling? Join our hybrid training course at Diamond Light Source, 7–12 Sept 2025! 🎓 For early-career EM/structural bio researchers 💡 Free academic places incl. meals, stay & travel Apply: https://t.co/bVQveWfsQQ
#CryoET #FIBmilling #Microscopy
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🥳 It's officially out!!! Curious how HIV-1 enters the nucleus to infect non-dividing cells? Check out our recent work now published in @NatureMicrobiol. Grateful to @EMBO for supporting my postdoc journey. @ZhenHou7 @GroupZhang @OxfordStrubi @eBIC_Diamond
Out Now! HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability https://t.co/536wnBx4Hp
#HIVResearch #ViralScience #Microbiology
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Our work @GroupZhang is now published in Nature Microbiology! @NatureMicrobiol Using cryo-CLEM and cryo-ET, we unveil the nuclear import of HIV-1 and the determinants of this mysterious process. Check it out! https://t.co/BEthQtEHhH
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🔬 New to cryo-ET & FIB milling? Join our hybrid training course at Diamond Light Source, 7–12 Sept 2025! 🎓 For early-career EM/structural bio researchers 💡 Free academic places incl. meals, stay & travel Apply: https://t.co/bVQveWfsQQ
#CryoET #FIBmilling #Microscopy
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🔥 We caught SARS-CoV-2 in the act of membrane fusion—frame by frame! Using cryoET, we reveal the entire fusion sequence in near-native conditions—and how S2-targeting antibodies slam the brakes on it. Don’t miss it 👉 https://t.co/64OWbETnW5
@OxfordStrubi @eBIC_Diamond
nature.com
Nature Communications - This study delineates the full sequence of SARS-CoV-2 spike-mediated membrane fusion and shows how S2-targeting antibodies inhibit this process, using a near-native...
Our study is out in Nature Communications! 🎉 We reveal the full sequence of SARS-CoV-2 spike-mediated membrane fusion & show how S2-targeting antibodies block it using cryoET in a near-native system. 🔬🦠 https://t.co/W0aV8gjgsv
#SARSCoV2 #CryoET #Virology #CryoEM #Antibodies
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In plants, the space between cells is a key battleground during infection 🦠 New research in @ScienceMagazine reveals that glycosyrin, produced by crop diseases, hides the disease by mimicking galactose – acting like a wolf in sheep’s clothing 👇 https://t.co/Kr34V0ltDM
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Just started our Next keynote - goto zoom if u hybrid! Valentina Loconte is the new Principal Beamline Scientist at B24 and joined us earlier this year @DiamondLightSou @ccp_em @instructhub and gets our B24 session at the BCI user meeting #BCIUM2025 going
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First keynote of the day from @DavidBSauer #bcium2025 …before coffee and chocolates from @DECTRIS_News @ccp_em @ccp4_mx @instructhub
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📢Prof Peijun Zhang is recruiting four PDRAs for the project supported by a recent Wellcome Discovery Award, to work on HIV-1 transport and host cofactor regulation. #cryoEM #cryoET Apply before 12 midday on 24 February 2025. https://t.co/UKrLGp1g51
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📢 Closing date fast approaching! Appply by Sunday 19 Jan for an in-person spot at "Wellcome-MRC Cryo-EM Structural Biology 2025 - March 03-07" - limited spots! @wellcometrust @The_MRC @eBIC_Diamond @DiamondLightSou & @Astbury_BSL @UniversityLeeds ⏳🔗 https://t.co/u5CZ3XDJS1
📢Apply by 19 Jan for an in-person spot! 📷 Join us March 03-07 at "Wellcome-MRC Cryo-EM Structural Biology 2025" @wellcometrust @The_MRC @eBIC_Diamond @DiamondLightSou & @Astbury_BSL @UniversityLeeds. https://t.co/u5CZ3XDJS1
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📢Apply by 19 Jan for an in-person spot! 📷 Join us March 03-07 at "Wellcome-MRC Cryo-EM Structural Biology 2025" @wellcometrust @The_MRC @eBIC_Diamond @DiamondLightSou & @Astbury_BSL @UniversityLeeds. https://t.co/u5CZ3XDJS1
📢 Apply now for the 'Wellcome-MRC Cryo-EM in Structural Biology 2025' @wellcometrust @The_MRC 📅 Join us March 03-07 @eBIC_Diamond @DiamondLightSou & @Astbury_BSL @UniversityLeeds for fundamentals in #CryoEM & #CryoET🦠 Apply by 19 Jan - limited spots! 🔗 https://t.co/XKIlF1Jz0q
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Upcoming Cryo-EM course at eBIC: 📢 Apply now for the 'Wellcome-MRC Cryo-EM in Structural Biology 2025' @wellcometrust @The_MRC 📅 Join us March 03-07 @eBIC_Diamond @DiamondLightSou & @Astbury_BSL @UniversityLeeds for fundamentals in #CryoEM & #CryoET🦠 Apply by 19 Jan '25 ⏳
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📢 Apply now for the 'Wellcome-MRC Cryo-EM in Structural Biology 2025' @wellcometrust @The_MRC 📅 Join us March 03-07 @eBIC_Diamond @DiamondLightSou & @Astbury_BSL @UniversityLeeds for fundamentals in #CryoEM & #CryoET🦠 Apply by 19 Jan - limited spots! 🔗 https://t.co/XKIlF1Jz0q
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🎉Well done to @eBIC_Diamond's Pete Harrison on a brilliant grid race win! 🎉 @quantifoil #cryoem #crystallography
Final conference of the year and what a pleasure to spend it @MRC_LMB with @britcryst BSG Winter Meeting. Lovely day discussing #cryoem and #crystallography, and congratulations to Peter Harrison @eBIC_Diamond for taking away the final grid race prize, with a fab 16 sec time!
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Thrilled about our giant virus (~2,300-pixel box!) in collaboration with @Gabriel_MFA & @sundberglr Huge thanks to EM @CICbioGUNE, @eBIC_Diamond and @RES_HPC (Malaga node). Stay tuned for virosphere and virus-host studies with a ONE HEALTH approach using cryo-EM/-ET @Ikerbasque
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A novel cryo-EM affinity-grid approach utilizing monodispersed single-particle streptavidin on a lipid monolayer is introduced to improve particle absorption, thereby addressing challenges like preferential angular distribution https://t.co/PlJo2KjTFG
@eBIC_Diamond @OxfordStrubi
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