Robert Rose, PhD, FHRS
@dysrhythmology
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Professor, University of Calgary, Deputy Director, Libin Cardiovascular Institute. Investigating the basis for cardiac arrhythmias and heart disease
Joined August 2018
“Atrial fibrillation is so common and so prevalent, it's really a huge challenge that affects millions of people around the world." Listen to this month's #CANetTickerTalk episode with Dr. Robert Rose and learn more about how his lab seeks to unravel the elusive causes of
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We're thrilled to share @CPKC’s Clear Rounds for Heart raised over $157,000 at the @SpruceMeadows 'Masters' on Sunday! The funds will support our Women’s Cardiovascular Health Initiative. Thank you CPKC! #CPKCHasHeart #SpruceMeadowsMasters
@ucalgary @UCalgaryMed @AHS_YYCZone
CPKC International at Spruce Meadows raises over $157,000 to support women’s heart health in Alberta: https://t.co/M7Jvmjdabr
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Fantastic!!
CPKC International at Spruce Meadows raises over $157,000 to support women’s heart health in Alberta: https://t.co/M7Jvmjdabr
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A pleasure to work on this with outstanding basic ( @SusanEHowlett Robert Rose) and clinical (Jon Howlett, @GAWHeckman ) scientists. Important problem in aged population, reviewed from bed to bedside. @Cardio_Girl @mmamas1973 @AmerGeriatrics @escardio @ACCinTouch @Dominik_Linz
Heart Failure With Preserved Ejection Fraction in the Elderly Population: Basic Mechanisms and Clinical Considerations ➡️ Read the August #CJC Article of the Month from @CJCJournals Editor-in-Chief @StanleyNattel: https://t.co/abhjPuH4Vj
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New publication on AF in aging and frailty: ACE inhibitors are protective. @LibinInstitute @UCalgaryMed Chronic angiotensin converting enzyme inhibition attenuates frailty and protects against atrial fibrillation in aging mice - Heart Rhythm
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Always a great pleasure to work with Rob Rose @dysrhythmology exploring how frailty sets the stage for late life heart diseases like HF and AF.
@SusanEHowlett and I have reviewed the effects of frailty on the heart in aging. Available here: Preclinical Studies on the Effects of Frailty in the Aging Heart - Canadian Journal of Cardiology
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Our latest 📰: Sex Differences in physical activity levels & sitting time in patients w/ atrial fibrillation (AF) 🔗 https://t.co/2s3PrDICQS 👏 @isabelarmarcal on leading the charge. Many women & men w/ AF did not meet the PA (60 vs 55%) but met the sitting time (70 vs 68%) recs.
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Atrial fibrillation is the most common heart rhythm disorder, but there’s a lot we still don’t understand about the condition. Findings from a CIHR-funded research team led by Dr. Robert Rose @UCalgary could lead to new preventive treatments. #HeartMonth
https://t.co/vCr3KP0ysk
cumming.ucalgary.ca
Team identifies receptor with important role in preventing atrial fibrillation
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Our new paper on natriuretic peptides and #AtrialFibrillation now available here: Natriuretic Peptide Receptor B Protects Against Atrial Fibrillation by Controlling Atrial cAMP Via Phosphodiesterase 2 | Circulation: Arrhythmia and Electrophysiology
ahajournals.org
BACKGROUND: β-AR (β-adrenergic receptor) stimulation regulates atrial electrophysiology and Ca2+ homeostasis via cAMP-dependent mechanisms; however, enhanced β-AR signaling can promote atrial...
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These authors won the #APSselect award in @ajpheartcirc for "Chronic testosterone deficiency increases late inward sodium current & promotes triggered activity in ventricular myocytes from aging male mice"👏 https://t.co/V3kRXzNHjx
@mmishrabio @dysrhythmology @SusanEHowlett
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New study demonstrates protective effects of GLP-1 on atrial fibrillation in a mouse model of type 2 diabetes via ion channel and antifibrosis mechanisms. https://t.co/6EaNYSl8rB
#AFib #EPeeps #diabetes #T2D #JACCBTS #CardioTwitter @dysrhythmology
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Once again, we're honored to be recipients of @CPKCrail’s #CPKCHasHeart #ClearRounds4Heart program @Spruce_Meadows which will support our efforts to advance personalized & precise cardiovascular health therapies. Read more at https://t.co/5KieHdf4ah
@UCalgaryMed @ucalgary
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September is Atrial Fibrillation Awareness month! #KnowYourRhythm #Epeeps #AtrialFibrillationAwareness @EPeeps_Bot @ACCinTouch @ArunRSridhar @DrRachitaEP @DrJCheungEP @KeepInRhythm @NazemAkoum @KTamirisaMD @MohitTuragam @DrIjeEkeruo @rajeshkabramd @drrakeshg1
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Our new publication on mechanisms of chronotropic incompetence and sinoatrial node dysfunction now available here: @LibinInstitute PDE4D mediates impaired β-adrenergic receptor signaling in the sinoatrial node in mice with hypertensive heart disease
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important information on personalized care for atrial fibrillation:
Atrial fibrillation phenotypes: the route to personalised care? Our latest editorial out in @Heart_BMJ We need to move away from a one-size-fits-all approach for atrial fibrillation @arunsau_ @LiborPastika @BalvinderHanda @ImperialEP @ImperialNHLI
https://t.co/6SNzr7zyQy
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Investigating the link between aging & arrhythmias, Dr. Lockhart Jamieson, PhD, aims to determine innovative therapies to prevent serious arrhythmias in the elderly. Jamieson is one of 16 #UCalgary postdocs to receive CIHR Postdoctoral Fellowships this year. Read more ➡️
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Important Na channel review here:
Our review published in this week's issue of #CardiovascularResearch The interplay of microtubule plus end binding proteins and #sodiumchannel interacting proteins mediates NaV1.5 delivery at subcellular domains summary ⬇️by @GA_Marchal
@CVR_TomaszGuzik
https://t.co/7OhQxzKc3Y
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Check out the last review about ryanodinopathies. Both gain of function and loss of function underlie fatal arrhythmia. CPVT and beyond. "RYR2-ryanodinopathies: from calcium overload to calcium deficiency." @EuropaceEiC
https://t.co/y3XX96EUFE
academic.oup.com
Abstract. The sarcoplasmatic reticulum (SR) cardiac ryanodine receptor/calcium release channel RyR2 is an essential regulator of cardiac excitation–contrac
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Great to collaborate with @SusanEHowlett and her team on this study: Chronic Testosterone Deficiency Increases Late Inward Sodium Current and Promotes Triggered Activity in Ventricular Myocytes from Aging Male Mice
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Wang et al. discovered the novel role of #FKBP5-deficiency in #HIF1a activation & its subsequent impact on the transcription of #NCX1. Learn more about the mechanism of NCX upregulation in #Afib at https://t.co/KR2Z3YDHR4
@JiaSongZeal @naliphd @xwehrens @JordiHeijman
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