William Scotton
@drwillscotton
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Neurologist with interest in disorders of movement and cognition. Follow me on https://t.co/xsqg9O9b3s
Brewood, England
Joined April 2018
**NEW PAPER ALERT** Delighted for the first work from the Pick’s disease International Consortium (PIC) to be published in Lancet Neurology.. (1/12)
thelancet.com
The Pick's disease International Consortium provides an opportunity to do large studies to enhance our understanding of the pathobiology of Pick's disease. This study shows that, in contrast to the...
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Introducing Kosmos: ‘AI Scientist’ That Makes Discoveries Overnight | ALZFORUM
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📢FLYER OUT The next Queen Square Basal Ganglia Club Meeting will host Prof. Maria Grazia Spillantini from @Cambridge_Uni and Prof. @GeorgeTofaris from @UniofOxford. 🌍@UCLIoN, London 📅03/12/2025, 4PM All welcome Please🔁 @kailashbhatia @UCLIoN_DCMN @MDC_IoN_UCL @UCLBrainScience
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Repetitive head injury can lead to the development of chronic traumatic encephalopathy (CTE), a neurodegenerative disease with unclear pathogenesis. In a new Science study, researchers discover high burdens of somatic small insertions and deletions in a subset of #CTE
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pleasure to be on #newsnight last night with @scott.mitchell3 remembering his fabulous wife, Barbara Windsor #dementia goals programme and urgent need to modernise dementia services to deliver disease changing treatments - the challenge is great but cannot wait #implementation
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We are excited to confirm with @CurePSP the scientific committee for Neuro26. This includes Dr Kat Bowles, Dr Ed Jabbari, and Professor James Rowe! They will be helping to shape the programme for the event in coming months. We'll be sharing more soon.
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Neuropathologic Changes in People With Essential Tremor With Dementia | Neurology
neurology.org
Background and ObjectivesProspective cohort studies have demonstrated elevated risks of incident dementia in patients with essential tremor (ET). The explanation for this enhanced risk of dementia in...
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Neurodegenerative disease does not respect the artificial silos of movement and cognitive specialism which we slot ourselves into as Neurologists .. Parkinsonism & Related Disorders
prd-journal.com
Visuospatial dysfunction is a common yet underappreciated non-motor manifestation of Parkinson's disease (PD) that significantly impacts quality of life and predicts cognitive deterioration. While...
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James et al. report the development of a highly selective, CNS-penetrant small molecule HDAC6 inhibitor that shows robust efficacy in preclinical models of ALS and FTD. https://t.co/RcwRvb8rZ0
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The next round of recruitment for our training and development programmes is now underway! 🔹 Starter Fellowships 🔹 Clinical Academic Research Partnerships 🔹 New Consultant Scheme 🔹 BHP Clinician Scientists Deadline Mon 19 Jan Find out more & apply: https://t.co/PUvxlgrOav
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As the WM Regional Investment Summit showcased, our city is at the heart of growing sectors like life sciences, thanks to fantastic projects like #Birmingham Health Innovation Campus and the pioneering work of partners like @unibirmingham, @BW_SciTech and @PHTA_Ltd
#InvestInBrum
Ahead of the WM Regional Investment Summit today, here's what Minister for Investment @jstockwood said about his visit to Birmingham Health Innovation Campus & @PHTA_Ltd a new facility within Birmingham Health & Life Sciences District, of which this University is a key player👇
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Come and work with us at RWT! Job advert for senior clinical fellow in the Neurology team
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Asymmetric Applause Sign in Corticobasal Syndrome: A Case of Clonic Motor Perseveration - Rafee - Movement Disorders Clinical Practice - Wiley Online Library
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Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor Antibodies: Clinical Features and Outcomes https://t.co/8PKDixdcMj
#NeuroTwitter #NeuroX
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Limbic Alzheimer’s co-pathology in multiple system atrophy is associated with cognitive impairment and diagnostic inaccuracy | Acta Neuropathologica
link.springer.com
Acta Neuropathologica - The clinical heterogeneity of multiple system atrophy (MSA) may, along with the primary aggregation of alpha-synuclein (α-syn), partly be shaped by co-pathologies, such...
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🧠Read the updated ABN guidelines for autoimmune myasthenia gravis - summarised in the infographic below. Highlights include👇 • Daily (not alternate-day) steroids • Early thymectomy for AChR+ MG (<50 yrs; consider ≤65 yrs) • Evidence for early rituximab • New targeted
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PhD opportunity for clinicians with myself and Sonia Gandhi @LabGandhi @TheCrick working on Multiscale Modelling in Parkinson’s. Details here: https://t.co/F7qELtzkDe
@ABNTrainees @MDC_IoN_UCL #parkinsons
crick.ac.uk
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AZP2006 in Progressive Supranuclear Palsy: Outcomes from a Phase 2a Multicenter, Randomized Trial, and Open‐Label Extension on Safety, Biomarkers, and Disease Progression - Corvol - Movement Disorders - Wiley Online Library
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Delighted to see this review out focusing the urgent challenges in neurocritical care: Refractory Status Epilepticus (RSE) -
advanced.onlinelibrary.wiley.com
Refractory status epilepticus (RSE) is a life-threatening neurological emergency with high rates of death and long-term disability, but treatments for it are often based on limited evidence. RSE is...
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New online! Progress and challenges in sporadic late-onset cerebellar ataxias https://t.co/qtq2lwodBI
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We developed a new PSD-based approach to characterize tremor & cortical myoclonus. OT, ET, DT & myoclonus form a spectrum of movement regularity. Combined PSD features differentiate conditions and distinguish ET from DT. @UCLIoN_DCMN @UCLIoN @MDJ_Journal
https://t.co/Bx7Ncdj4mm
movementdisorders.onlinelibrary.wiley.com
Background The hallmark feature of tremor is rhythmicity, which can be quantified using power spectral density (PSD) analysis. However, tremor exhibits considerable variability, ranging from highly...
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