 
            
              Gian Manuel Jmz Rdz
            
            @drgianma
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              Cardiólogo. PO-ICU #congenitalheart #interventionalcardilogy 🇲🇽 #structuralheart UMC Utrecht 🇳🇱 #cardiotwitter #radialfirst
              
              Joined November 2018
            
            
           The LMCA saga continued! 🔭In the OCTOBER trial, OCT guided PCI in true LM bifurcations was associated with a non-significant improvement in MACE - following the main trial. 🔥Even tough the LMCA ostium was difficult to visualize, USD in the edge was frequent! #TCT2025
          
          
                
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             PROCTOR trial: Post-CABG patients with graft failure undergoing PCI of an SVG had a lower 1-year MACE risk than those undergoing PCI of a native vessel. #TCT2025 View the slides here:  https://t.co/Gxk0tHMVJw 
          
          
                
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             Revascularization in Ischemic Left Ventricular Dysfunction: a pathophysiology-guided, evidence-based approach Trials of routine coronary revascularization for iLVD have shown neutral results except for a benefit of CABG emerging beyond 5 years from surgery, supporting a 
          
                
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            #TCT2025 LBCT Takeaways Thanks to all investigators & authors for advancing our field
          
           Trip this weekend to San Francisco for #TCT2025 Glad to be part of this global scientific program and to present some of our collaborative research including one featured in the Late Breaking Clinical Science session. Looking forward to learning & meeting colleagues worldwid 🌎 
            
                
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             Regarding this review, I’m sharing our publication on the V-LA #ECMO configuration in @asaiojournal. Initially inadvertent and not without risks, yet with remarkable potential benefits:  https://t.co/Qdj3f4fZX0 
          
           Patent foramen ovale (PFO) is present in approximately 25% of all adults and is a common cause of stroke in young and middle-aged patients. 📝 This Review discusses PFO-associated stroke management.  https://t.co/yr4xTLbuXh 
            
            
                
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             iMODERN Trial (NEJM/TCT 2025) In STEMI + multivessel CAD, immediate iFR-guided PCI was not superior to deferred stress CMR-guided PCI at 3 yrs (death/MI/HF HR 0.95). ~44 % iFR positive vs 22 % CMR positive. Stroke 3.7 %→1.3 %. ➡️ Physiology works, but timing may not matter. 
           Presented at #TCT2025: In STEMI with multivessel disease, immediate iFR-guided PCI of nonculprit lesions was not superior to deferred cardiac stress MRI–guided PCI in reducing death, reinfarction, or hospitalization for heart failure at 3 years. Full iMODERN trial results: 
            
                
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             Sharing the results of The PROMISE Trial - just released at TCT in San Francisco - investigating the benefit of stratified treatment in MINOCA @RoccoMontone @ehj_ed
             https://t.co/Np3doQWaYm 
          
          
                
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             TCT 2025 LATE BREAKING CLINICAL TRIALS: One LINER SUMMARY 📸 AT A GLANCE ⭐️ What a phenomenal scientific meeting! Congratulations to all the presenters & leaders for their innovation, hard work and knowledge sharing. Thank you @TCTConference @TCTMD @crfheart team for a 
          
                
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            #TCT2025 @TCTConference @crfheart 10 year results of Noble Trial 🧨PCI vs. CABG: similar all-cause mortality 🧨No difference at 0-5 and 5-10 years 🧨In ACS: PCI associated with lower mortality 🧨SYNTAX score: no association with mortality
          
          
                
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             SELUTION DeNovo - non inferiority for TVF at 1 yr demonstrated. Randomisation before lesion prep ➡️ 20% DES use in DEB arm ➡️ 50% non inferiority margin of overall tvf in both arms !!!!! ➡️ TVF 4.4 vs 5.3% in des and deb arms This is a landmark moment- analogous to introduction 
          
                
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             Game-changing balloon-expandable #TAVR platform MiRus® #Siegel valve 30d EFS presented #TCT2025 by @PradeepYadavMD ! - Rhenium frame nickel free, porcine dry pack tissue with anticalcification - 8F expandable sheath - Short height but high radial strength - PVL skirt - 
          
                
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             This is a truly historic moment. The results from this pivotal trial evaluating a fully percutaneous transcatheter mitral valve replacement technology has opened a new treatment option for patients who are not good candidates for surgery or TEER. This is a remarkable milestone 
          
                
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             Not all secondary #Mitral #regurgitations are equal. Careful assessment of the mechanism — ventricular vs. atrial, tethering vs. annular dilation — is essential to guide therapy. As @hahn_rt reminds us, precision imaging leads to precision intervention. #TCT2005 @crfheart
          
          
                
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             Sirolimus-Coated Balloon Meets Mark in De Novo Lesions and ISR: SELUTION  https://t.co/l36vzx9YiK 
          
          
                
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            #cardiotwitter #TCT2025 our multicenter data on saline vs contrast OCT being presented today by @SanyaChhikara As OCT technology advances, with new systems offering pullback speeds of up to 100 millimeters per second, the data provided in this study become increasingly pertinent
          
          
                
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            @MayraGuerreroMD ⚖️ TAVR-first or SAVR-first? #TCT2025 🩺 TAVR-first:✅ Lower mortality & stroke rates (1–10 yrs)✅ Less AF, shorter stay, better hemodynamics🫀 SAVR-first:✅ More data on durability & valve-in-valve options✅ Root enlargement possible @crfheart
          
          
                
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