Deepak Kumar
@deepakdbg90
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Research scholar at TAU, Israel, exploring the role of #CRISPR in microbial evolution, #Antifungal resistance, #Ph.D. student, #Maithil
Joined August 2013
New insights about antiviral immunity!. We show that a TIR–SAVED effector from a Type II #CBASS system can function independently of its cyclase, by sensing a host-conserved signal, previously linked to osmotic stress. Upon sensing this signal, the effector depletes NAD⁺ and.
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RT @NatureMicrobiol: Out Now! Structure of an archaeal ribosome reveals a divergent active site and hibernation factor .
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RT @pacyc1841: Prophages block cell surface receptors to preserve their viral progeny | Nature
nature.com
Nature - Zip promotes the accumulation of free phages in bacterial lysogen communities, safeguarding phage progeny.
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RT @cellhostmicrobe: Phage counter-defense repertoires:.New work IDs broad & specific anti-defense genes in variable regions of Pseudomonas….
cell.com
Costa, van den Berg, Esser, et al. identify two broad and three specific anti-defense genes by examining variable regions of Pseudomonas phage genomes. These inhibitors neutralize diverse bacterial...
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RT @protasov_evgeni: Archaeal virus entry and egress.Archaea also have viruses and they are cool! .#microbiology #virology #virus #viruses….
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RT @HsiehYp: Exciting news! I am launching the Lab of Polymicrobial Interaction & Evolution @IPMBSinica @AcadSinica! 🎉 Our brand-new websit….
labofpie.org
We study the mechanisms of cross-kingdom microbial competition and how it influences microbial evolution and interaction with hosts
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RT @crypticprophage: New type IX toxin/antitoxin system, anti-phage system Clover, where antitoxin produces 5′-trip….
biorxiv.org
The cellular nucleotide pool is a major focal point of the host immune response to viral infection. Immune effector proteins that disrupt the nucleotide pool allow animal and bacterial cells to...
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RT @pacyc1841: Immune-deficient bacteria serve as gateways to genetic exchange and microbial evolution.
biorxiv.org
Horizontal gene transfer plays a key role in bacterial evolution, yet its efficiency under natural conditions, especially between genetically distinct strains, remains unclear. Using Staphylococcus...
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RT @biorxiv_micrbio: Identifying phage proteins that activate the bacterial innate immune system #biorxiv_micrbio.
biorxiv.org
Bacteria have evolved sophisticated antiphage systems that halt phage replication upon detecting specific phage triggers. Identifying phage triggers is crucial to our understanding of immune signal...
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RT @biorxiv_micrbio: Histone diversity in the archaeal domain of life #biorxiv_micrbio.
biorxiv.org
Archaea represent a distinct domain of life that is genetically and biochemically unique from bacteria and eukaryotes. Two-thirds of all archaea encode histones, proteins that are ubiquitously used...
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RT @biorxiv_micrbio: Integrative Modelling of Innate Immune Response Dynamics during Virus Infection #biorxiv_micrb….
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RT @NatureMicrobiol: Out Now! Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like a….
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RT @ugophna: Exciting work by @deepakdbg90 showing that Cyclic di-AMP, a cellular molecule produced by #archaea and Gram-positive bacteria….
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RT @protasov_evgeni: Biogenesis, function and evolution of the archaeal S-layer.#microbiology #archaea #CellBiology..
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RT @SternbergLab: New pre-print(s) from the Sternberg Lab in collaboration with @LeifuChangLab! We uncover an unprecedented molecular mecha….
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RT @nitinchandra25: If you preserve your mother tongue, you can bring these positive change and boost a lot of things like,. 1. Local Econo….
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RT @SternbergLab: Our latest story is now online @Nature! We discovered a phage defense system that deploys kilobase-long DNA homopolymers….
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RT @RomilaMoirangt2: Super exciting 🥳.First review as first correspondence author during my PhD. Many thanks to my PI @Yotam_BarOn for his….
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