Kelly Dawe
@corncolors
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Thank you André for hosting me. It was great to visit Max Planck and meet all the great scientists and see the wonderful facilities. Also nice to see the sights of Cologne.
I am very grateful and glad for the visit of Kelly Dawe @corncolors to @mpipz_cologne as our special seminar speaker! Thanks a lot for the inspiring discussions 🙌
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And here is my perspective on the new human artificial chromosome work. The methods deployed by Gambogi et al should be directly applicable to plants.
science.org
Constructing human artificial chromosomes in yeast avoids unintended multimerization
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Ben Black's lab describes a superior method for preparing human artificial chromosomes. The chromosomes are small enough to be engineered in yeast, but large enough to carry multiple genes and segregate like normal human chromosomes in cultured cells.
science.org
A quarter century after the first human artificial chromosomes, a solution to their uncontrolled multimerization is achieved.
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Very pleased to see our cenh3 haploid inducer being used to improve commercial maize lines!.
nature.com
Nature Plants - An efficient method of cyto-swapping by haploid induction using a CENH3 mutation is reported in maize, to convert commercial germplasm to cytoplasmic male sterility for hybrid seed...
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RT @jefowlerjr: New! Methylation-controlled gene regulation in maize pollen, led by Jonathan Gent (@corncolors group). Tldr: Two maize DNA….
biorxiv.org
Although DNA methylation primarily represses transposable elements (TEs) in plants, it also represses select endosperm and pollen genes. These genes, or their cis-regulatory elements, are methylated...
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RT @uga_plantbio: We’re hiring! We’re searching for an Assistant Professor in Plant Synthetic Biology to start Aug 1, 2024. The position wi….
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RT @TsaiLabUGA: Out now @plantjournal 717 genome-not one but two T2T assemblies for P. tremula & P. alba @phytozome! Creative work by @RanR….
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RT @hendersi: Teosinte Pollen Drive guides maize domestication and evolution by RNAi very beautiful work from Marti….
biorxiv.org
Meiotic drivers subvert Mendelian expectations by manipulating reproductive development to bias their own transmission. Chromosomal drive typically functions in asymmetric female meiosis, while gene...
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RT @charliesousbois: Great coverage of apomixis research in this headline news article this week @ScienceMagazine.h….
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Including two of my favorite colleagues and scientists, Luca Comai (@lucacomai) and Sundar. Richly deserved!.
We are thrilled to announce the election of 120 members and 23 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research. Congratulations to our new #NASmembers! #NAS160
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And congrats to Jianing Liu @ljn017 for following through on this difficult paper, years after graduation.
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Much of the maize pan-genome is ancient. We show that about a third of the pan-genome diverged earlier than ~100 kya and another third diverged ~10-30 kya, with centromere haplotypes appearing as evolutionary strata
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A nice summary of our work on maize synthetic centromeres by @hendersi.
New Article: "Synthetic maize centromeres transmit chromosomes across generations" N&V: "Plant genetics: Creating synthetic maize centromeres" Based on a LexA–CENH3 fusion; stably inherited and self-sustaining neochromosomes.
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Our successful effort to create synthetic maize centromeres is now published! We hope to use this method to alter karyotypes in maize and other plants. And one day engineer entire chromosomes.
nature.com
Nature Plants - Dawe et al. report a protein tethering method for recruiting Centromeric Histone H3 to synthetic repeat arrays. Newly recruited Centromeric Histone H3 organized functional...
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Meghan Brady.
It’s corn! I can’t imagine a more beautiful thing. Check out our latest article here:
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RT @pcronald: After more than 20 years of effort perennial rice (PR) has become a reality. PR produced yields in each of four consecutive y….
nature.com
Nature Sustainability - The environmental and socioeconomic costs of annual crops challenge their sustainability. This study reports the successful breeding of perennial rice and assesses its...
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RT @LabShih: We are excited to share new work from our group at .@UCBerkeley. We characterized hundreds of plant transcription factors, tha….
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RT @MaizeGDB: Stanford geneticist Dr. Virginia Walbot has been selected as the 2023 recipient of The Barbara McClintock Prize for Plant Gen….
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