CuauhtemocLC
@cliconac
Followers
418
Following
3K
Media
43
Statuses
1K
Me: Assistant Professor @IBT_UNAM #AppliedMicrobiology #IndustrialGenomics #ClinicalMicrobiology #OpenWaterSwimming #Wine #Food
CDMX
Joined May 2010
FuNTB: A functional network clustering tool for the analysis of genome-wide genetic variants in... - https://t.co/JFsMVuO22c
#ScholarAlerts
0
0
0
📌 REGISTRO ABIERTO ¡Les invitamos a formar parte de los TIB2025! Tendremos los talleres: - Pangenómica y Filogenómica Microbiana (presencial) - Introducción a Python e IA (en línea 🌐) Convocatoria: https://t.co/xmRpwJJDeG
@ccg_unam @RBioinformatica @lcgunam
0
12
16
Exploring and expanding the natural chemical space of bacterial diterpenes | Nature Communications
nature.com
Nature Communications - Unlike that in plants, fungi, and marine animals, bacteria are vastly underrepresented in the production of terpenoids. Here, the authors report a systematic screening of...
0
7
20
Meet mandimycin, a new polyene antifungal with broad-spectrum activity and a unique mode of action targeting fungal cell membranes. 🦠🔬 #Antifungal Out in @Nature
https://t.co/aaFcLLylzv
nature.com
Nature - Mandimycin, a polyene macrolide, exhibits strong antifungal activity and possesses a mode of action that is distinct from other compounds of this class.
1
39
117
Computation-aided designs enable developing auxotrophic #metabolic #sensors for wide-range glyoxylate and glycolate detection—spearheaded by @enricoorsi w/a choral assembly of cool collaborators @LabNikel @NatureComms #SynBio #OpenAccess
https://t.co/IXyVsaurt2
nature.com
Nature Communications - Auxotrophic metabolic sensors (AMS) are vital for bioengineering but are often time-consuming to develop. Here, the authors present a workflow for designing versatile AMS,...
0
8
41
Discovery of a family of bile acid-methylcysteamines @Nature @Cornell @group_Schroeder #activitymetabolomics A nuanced interplay between host and microbiota in regulating bile acid signaling pathways through FXR with a new target for metabolic disorders https://t.co/VvnLBbGJ9A
0
14
48
~5y ago, @BDragonMaster @serina_robinson @marnixmedema & I teamed up to make a better NRPS A-domain specificity predictor. @Challis_Group & others joined along the way to add some very cool insights. Very proud of this work. Check it out now on biorxiv!
1
11
30
2024 FDA approvals https://t.co/mEpJ4Oc4f4 The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first MASH medicine and much more - find out about them in our annual round-up
4
96
259
Breast milk for adults: wellness elixir or unscientific fascination? | Well actually | The Guardian
theguardian.com
Researchers have found more promising ways the infant food can benefit health – aside from being a nutritional supplement and supposed hangover cure
0
0
0
New review paper is out! (Just in time for #NationalBreastfeedingWeek!) I learned loads writing this review with immunology collaborators @basbees & Jean Marshall... 🧵 https://t.co/P5XrZYgrOc
11
46
124
Smart microbes are rapidly emerging as potential therapeutic interventions. Srivastava and Lesser in MBT discuss the potential of engineered bacteria for ensuring healthy lives and promoting well-being for all ages, aligning with UN SDG 3. Read: https://t.co/MGT27oRksr
1
10
22
Designing strong inducible synthetic promoters in yeasts "inducible promoters that achieve a > 1000-fold induction" https://t.co/qLeWXiKGIk
1
27
134
In @eLife: Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
elifesciences.org
An approachable framework for the scalable implementation of proteome-wide thermal shift assays to assess drug mechanisms of action.
0
1
4
We are excited to announce that our collaborative work on the curation of the MIBiG 4.0 database has been successfully completed and is now published in Nucleic Acids Research! 🔗 The paper is publicly accessible here: https://t.co/lCwSqgn7Wg
@NABI_India @thinkgenome
academic.oup.com
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
4
3
24
📢Our final issue of 2024 is now online! 🔓Check out the #OpenAccess review behind the front cover by Vânia M. Moreira & co @UnivdeCoimbra covering the last decade of bi- & tricyclic diterpenoids research in search of leads against infectious diseases https://t.co/0zjdLjsuoT
0
2
3
An explainable deep learning platform for molecular discovery @NatureProtocols 1. This study introduces an explainable deep learning platform for molecular discovery, bridging the gap between powerful predictive tools and actionable chemical insights. 2. Traditional deep
1
18
92
Our new baby just got home 🐣#AstralOrbitrap for High throughput #Proteomics @CBFTEC @IngenieriasTec @thermofisher #proteomeDiscovery #biotechnology
2
2
23
0
1
9
Nice to see this wonderful story published. Congrats to Erin and Michael and all involved. Directed Evolution of an Adenylation Domain Alters Substrate Specificity and Generates a New Catechol Siderophore in Escherichia coli https://t.co/JE4XJNshfU
pubs.acs.org
Nonribosomal peptide synthetases (NRPS) biosynthesize numerous natural products with therapeutic, agricultural, and industrial significance. Reliably altering substrate selection in these enzymes has...
0
8
29
