Christopher Kelly
@ckellzchem
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Principal Scientist @ JnJ and Lecturer @ Penn. Lover of old school synthesis, punk rock, astronomy/space, gardening/succulents, and Camaros. Views are my own.
Philadelphia, PA
Joined September 2017
Super proud of how strong @JNJInnovMed collab w/ @LevinChem and @group_levin has become! Our 1st foray for our collab on skeletal edits yielded an cool approach to the synthesis of N-Alkyl Pyrazoles from a non-intuitive SM, isothiazoles! Truly an honor to have been involved in
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Come join us on Mole Day for a great lecture and special treats!
The long-awaited 2nd POCC lecture of the season is tomorrow (October 23) at 7:30pm, with a reception beginning at 6:30pm! We hope to see you there!
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The long-awaited 2nd POCC lecture of the season is tomorrow (October 23) at 7:30pm, with a reception beginning at 6:30pm! We hope to see you there!
Join us on October 23rd for our first industry seminar of the semester starring Dr. Andrew DeAngelis from FMC, where he will be sharing the discovery of bicyclic carboxamides and their role in pest control! We hope to see you there in a few weeks!
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One of the most used photoredox reactions in pharma is the deoxygenative cross-coupling using deoxazole ("NHC"), and the industry wide uptake of this diversity generating transformation has just been brilliant to see. This new paper from Johnson & Johnson (by Shane Plunkett and
pubs.acs.org
Advancements in the field of C(sp2)–C(sp3) cross-coupling using alcohols as feedstocks have resulted in widespread adoption in analogue synthesis. Using high-throughput experimentation, an in situ...
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Harnessing gem-Diboron Radicals: A Ni-Catalyzed Reductive Coupling Platform for Diverse sp3-Rich Molecular Architectures (@JOC_OL): https://t.co/t4BdpsjxB4.
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Overriding Norrish Type II to Access Cyclopropanols | Journal of the American Chemical Society @RousseauxGroup
@chemuoft
@UofT
@UofTArtSci
pubs.acs.org
The propensity for photoexcited aryl ketones to undergo 1,5-hydrogen atom transfer (HAT) reactions is a fundamental process in organic synthesis and polymer degradation. Since its discovery in 1958,...
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Super excited to have POCC off to a great start building on a fantastic year last year championed by @jamilligan12 . Courtney Roberts (our first speaker and Students's Choice lecturer) gave an awesome talk on the work her group is doing in advancing our understanding of aryne
We hope everyone had a great time last night at our kickoff seminar of the 2025-2026 series, our Student Choice Lecture featuring Courtney Roberts! Tune in again next month (October 23rd) to hear some more incredible chemistry shared by Dr. Andrew DeAngelis from FMC!
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Another awesome joint venture with @TrevorAHamlin Was great to work with the talented students Trevor is mentoring and yet another great @UConnChem alumni collab! Looking forward to future endeavors!
Excited to share our group’s latest preprint: a study on methyl radical additions to monosubstituted alkenes. @YumanHordijk, T. Kaptein, @EvaBlokker, @ckellzchem do a fantastic job clarifying the “why” behind radical reactivity and regioselectivity. 🔥 https://t.co/CLWKcng900
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Looking forward to a great kick off! Please join us!
Join us at our first meeting of the 2025-2026 POCC season THIS Thursday, September 18th, for the Student Choice Lecture featuring Courtney Roberts! We hope to see you there later this week!
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Add a little (pumpkin) spice to your Fall semester by attending our first seminar of the season! Professor Courtney Roberts will be speaking on all things arynes at our Student Choice Lecture on September 18th, 2025, at 7:30pm. We hope to see you there!
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Like all good things, ACS DC 2025 has ended and the experience there is one for the record books. This conference was particularly special because myself, Paramita Deria, and Fangzheng Li got to see the fruits of our labor with the resounding success of our first ““Accelerating
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Super humbled and thrilled by this, our 4CzIPN protocol is the most accessed protocol at Org Synth! Written and executed with two star undergrads, Saskia and Kisha, was one of my favorite publications during my time at @VCUChemistry !
Top Ten Organic Syntheses Articles (Vol 65 to present) accessed during 2024 (1) Kelly Carbazole Photoredox Catalyst OS 2019, 96, 455 (2) Taber Oxone Preparation OS 2013, 90, 350 (3) Miyaura Bis(pinacolato)diboron OS 2000, 77, 176 (4) Boeckman Dess Martin Reagent OS 2000, 77, 141
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Really looking forward to what is turning out to be an amazing year. Please join use for some great seminars in the great city of Philadelphia!
If you attended the ACS meeting in DC and are looking to keep the chemistry flowing, look no further! POCC is BACK for another year of outstanding seminars with an excellent lineup for the 2025-2026 season, chaired by Chris Kelly (@ckellzchem). We hope to see you in September!
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Come one, come all...to our FULL DAY (!) joint symposium between the ORGN and AGRO divisions at ACS DC featuring a selection of fantastic chemists from across industry and academia. Super excited for all the seminars in this symposium, especially my colleague Rosaura
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The final version of our paper is available, and open access! If you are interested in radical decarboxylative approaches or small rings, please have a look. @snsf_ch @KatayevL @pushingarrows @DCBPunibern
Our Iron-photocatalysis approach to small-ring transfer is now live in its final form @angew_chem! Great collaboration with Julian West @pushingarrows. Congratulations to everyone involved 🚀 @DCBPunibern @SwissChemistry #chemistry Check it out here 👉 https://t.co/4sjzYrIDQf
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Always a pleasure to continue to work with @UConnChem alumni! @TrevorAHamlin and I worked extensively on computational modeling during our grad school days and its great to be talking shop again with him and his team! Congrats to all involved and hopefully more to come soon!
This work has been published in @JOC_OL! 🖥️ 🧪 Congrats to the team! @YumanHordijk Baart Waaijer, @ckellzchem ! 🔥 https://t.co/eicx0L7zBB
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Synthesis and Application of Geminal Halodiborylalkanes: Recent Advances and Future Perspectives (@ChemCatChem): https://t.co/eSBOxfqxW5.
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Really enjoyed kicking off our 2025-2026 @JNJNews Spring House seminar series with @andrei_yudin from the University of Toronto. Andrei gave a great talk on the ‘dark space’ of macrocyclic peptide conformations & ‘frame-shifting’ our mentality to heterocyclic construction .
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Super thrilled to finally see this collaborative work between @JNJNews 's DPR, CCAP, and ISD groups with @LevinChem and @group_levin live on @NatureChemistry ! Here's to more fruitful endeavors in the world of molecular editing and deaminative functionalization! Link:
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Words can't describe our feelings! In @ScienceMagazine, we present a flow method to prepare CF3-X anions on demand using organic precursors and CsF, avoiding #PFAS use in the process. 🔗 https://t.co/syGixy4Po4 This allows for precise introduction of these groups at any stage!
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A mechanistically interesting strain-release cascade reaction with BCBs ⚡️Synthesis of Oxa-spiro-bicyclo[2.1.1]hexane by Au/Sc Relay Catalysis | Organic Letters
pubs.acs.org
A new Au/Sc relay catalysis approach has been developed for the rapid construction of oxa-spiro-bicyclo[2.1.1]hexanes under mild conditions. This cascade reaction proceeds via a gold-catalyzed...
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