Chronic diseases were more strongly linked to suicide attempt, while severe conditions and psychiatric polygenic scores were more associated with suicide, indicating overlapping but distinct risk factors for attempt and death by suicide. https://t.co/0BKIBCHPZo

🧬💥 Do the genetics that make you develop a disease also help you survive it? Not much. Our new @NatureGenet including 9 disease and 7 biobanks shows: • Susceptibility variants ≠ survival • PRSs for onset weak at predicting survival • Lifespan PRS predicts survival better

Very happy to share our new paper now on @medrxivpreprint: “Genetic risk effects act in sets”, a great effort led my PhD student @JolienRietkerk, and performed together with collaborators @andywdahl, @AndrewSchork, @jonathan_flint1 etc. Thread 1/n

🙌 And to @NCRRCBP, Marianne Pedersen, @sussieantonsen, Emil Pedersen, @HorsdalThisted, Jean-Christophe Debost, @BoPreben, Liselotte Petersen, @bvilhjal, Jørgen Feldbæk Nielsen, Jeppe Klok Due, Anders Søgaard, @christian_igel, Wes Thompson, Chun Fan, @WrayNaomi, @John_J_McGrath

Oof. Polygenic scores for IQ lose 75% of their explained variance when adding family controls, even worse than the attenuation for Educational Attainment. These are the scores Silicon Valley is using to select embryos 😬. A few thoughts on this study ...

The New York Times recently had an article on IVF and embryo selection which I think buries a few important ledes about these products ...

It's amazing how Trump just made the Euro strengthen by more than 2% in one day, and with it the size of the EU economy.

@orthonormalist oops, fixed. Now we get that nice straight line

russia is not on the US tariff list because the US does not trade with russia, says the US Treasury Secretary. In fact, they do trade, even more than with Mauritius or Brunei, for example, which were added to the tariff list. Cuba, Belarus, and North Korea were also not

I wrote about how population stratification in genetic analyses led to a decade of false findings and almost certainly continues to bias emerging results. But we are starting to have statistical tools to sniff it out. A 🧵:

This place used to be great for learning about the latest things going on in science. Now it feels completely overrun MAGA fanatics and extremist bots. 🤮

Truly remarkable with Vice President JD Vance 🇺🇸 saying that 🇩🇰 “is not a good ally” and indicates 🇺🇸 will do whatever with 🇬🇱 in spite of “the screaming of the Europeans”.

A new preprint from Estonian biobank reporting an impressive range of genetic findings based on GWAS of 4,884 clinical end points in ~200k Estonian individuals. Alekseienko, Abner, et al. medRxiv https://t.co/fZTaAly7hS Like Finnish population, Estonian population has also

gsMap paper online. Source code: https://t.co/J1YnfnJ1j6. Results visualisation website: https://t.co/mVKmv21wbZ.

The top 0.1% of Americans control $22 trillion in wealth. The bottom 50% of the country controls $3.8 trillion in wealth. Read that back. Is it any wonder why so many think the system is rigged?

@FoxNews @FoxNews shame on you for this title making people read the reality backwards. UKRAINE HAS AGREED TO THE CEASEFIRE. russia has not. Hence we need to continue to protect OUR CHILDREN FROM BEING KILLED.

Canada is starting to get really angry at Trump. Their Foreign Minister Melanie Joly is serious about standing up to Trump's attempt to annex her country and doesn't think it's funny. "If the U.S. can do this to us, their closest friend, then nobody is safe." She also

A big anti-Trump rally took place in Nuuk, Greenland, protesting Trump’s insane calls for annexing the island to the United States. https://t.co/UOFeQ1DuqP

The beginning of the demonstration at 1pm Nuuk, Greenland 🇬🇱 March 15, 2025

@atrupar This is a Norwegian Church in Greenland. A wedding in 1408, between Sigríður Björnsdóttir and Þorsteinn Ólafsson. The Curch is much older. How old is the US again?