Happy to share our recent #review on #allosteric #coupling and #ligand #bias in #GPCR. #allostery @cyclic_Andreas @MDC_Berlin @FU_Berlin

Here, we present MDPath, a novel tool to study allosteric communication pathways within protein structures: Unraveling Allosteric Communication Paths of Drug Targets through Molecular Dynamics Simulations.

It is a great pleasure to share that our extensive review on "The Chemistry and Biology of the Tetrodotoxin Natural Product Family" has been accepted for publication at Angewandte Chemie: https://t.co/Au6xajx05a.

📣 We are hiring a PhD candidate in computer-aided drug design with passion for MD simulations and ion channels to join our enthusiastic team at the University of Münster. For more details and information how to apply, please visit:

A bio. tools collection of online resources for GPCR research https://t.co/gjREPN7SfZ Thank you @bermudez_lab for leading this, happy to contribute

That's a great resource!

Interested in doing a #PhD in the field of #cellbiology and #pharmcology? We have an open PhD student position and develop novel optical to investigate how heterotrimeric #Gproteins enable #GPCR-specific signaling. Please repost :) https://t.co/AfpZBet2hO

Excited to share our work on GPCR antagonism: Contrary to popular belief, inverse agonists can bind to and act via GPCR:G protein complexes. We show this at kappa-opioid receptors by cellular, radioligand binding and cryoEM studies. A 🧵: @USC @USCDornsife https://t.co/7EN1pVc3Fd

Very honored to receive the Best Poster Award for the ONCORNET session for presenting dynamic models of ACKR3 to understand how it can bind opioid peptides. Special thanks go to the @GPCRForum team for organizing this fantastic virtual meeting! @PharmaCampus_MS @bermudez_lab

BitterDB: 2024 update on bitter ligands and taste receptors https://t.co/dHtQuWIq3Z - Please visit to find what is #bitter, to humans and other species

📢 Last Chance! Today is the final day to submit your abstracts for the 1st GPCRForum Conference! Get ready for an exciting program featuring cutting-edge science, inspiring talks, and top GPCR experts! Don’t miss out—check the program and submit today! https://t.co/UIGkADI4lU

📢 JOB ALERT 📢 My team @molecularML is searching for a #postdoc with a background in medicinal chemistry! 👩‍🔬👨‍🔬🧪 Do you have the experience? Are you eager to contribute to #AI for discovering new drugs? 👉Then DM me! Funded by @ERC_Research and located at @TUeindhoven 🚀

We are excited to share the update that our project OpenMMDL has been accepted as MDAKit, now available at MDAnalysis https://t.co/0QwMFjpIoW and via conda forge https://t.co/XdBSFBq1SR @openmm_toolkit @VTalagayev @YuChen_istry @Habacef @jchodera @orbeckst

We recently launched our seminar series for the #ChemTrap consortium (Topical Program @uni_muenster) with an amazing talk by @yifan_ucsf @UCSF on the structural studies of TRPV1 channel #cryoEM #resolution_revolution. Stay tuned for more updates!

Please check out the final version of our paper, featuring new cyclic peptides that beautifully mimic the actions of the opioid receptor nanobody. This has been a very fun project and we look forward to continuing our work with these new ligands. Congrats to all authors.

Muscarinic receptors never get boring! Here, we report the first photoswitchable allosteric modulators for a class A GPCR. @chem_pharm_ms @IBECBarcelona @Uni_WUE

#OnTheCover Photo-BQCA: Positive Allosteric Modulators Enabling Optical Control of the M1 Receptor (Michael Decker and co-workers) https://t.co/JEFgF1aJ3f @IBECBarcelona #openaccess @uni_wue https://t.co/YFUPyFnL72

Fantastic opportunity!

Tomorrow is THE DAY! 🎉 We're kicking off the #4th_Transatlantic_ECI_GPCR_Symposium. This is the final reminder for registration! Besides the amazing keynote speakers, and career and lunch/dinner panelists, we have wonderful #ECI speakers who will present their latest research!

A µ-opioid receptor modulator that works cooperatively with naloxone | Nature https://t.co/QaZCobFl6a

If you have a background in chemistry, biophysics, cell biology and ambitious for research we are searching for you!! Apply to do your PhD with us! https://t.co/d1683BQFY7