Asli Sahin
@aslisahin2205
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Joined April 2022
Beyond happy that our latest work is now available at @NatureComms!🎉 In this work, we present an evolutionary approach to enzyme kinetics and introduce our computational framework to explore the catalytically optimal enzyme.
Goodmorning :) Excited that our latest work ( https://t.co/Q6QZJWAfKz) just got published at @NatureComms! In this work, we introduce a framework to explore the catalytically optimal operating conditions of any complex enzyme mechanism from an evolutionary perspective.
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Very excited the first @NCCRMicrobiomes -wide review is now out @ASMicrobiology! Check it out here: https://t.co/kmaDY27HzR
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Very excited our latest work is now available at @ScienceMagazine Many congratulations to all the authors and a big thank you to our colleagues at the Vorholt Lab for the excellent collaboration, enabled through the @NCCRMicrobiomes More:
science.org
Interactions between plant-associated bacteria are recapitulated by experimentally informed genome-scale metabolic models.
Tell me what you eat, and I will tell you how you compete. A new study by the Vorholt Lab @Microbio_ETH @ETH_en with @realLCSB at EPFL predicts bacterial interactions with high accuracy using metabolic modelling. More: https://t.co/B1lsx180G0
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Ever thought about how evolution shapes enzyme binding mechanisms? Exited to share this work of @aslisahin2205 @realLCSB with @Vassily_13. We show that cellular concentrations and thermodynamics determine the optimal binding sequence and enzyme saturation.
Goodmorning :) Excited that our latest work ( https://t.co/Q6QZJWAfKz) just got published at @NatureComms! In this work, we introduce a framework to explore the catalytically optimal operating conditions of any complex enzyme mechanism from an evolutionary perspective.
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Earthquake in🇹🇷 and 🇸🇾 - The student association Turcopoly is holding a donation stand for the victims of the #earthquake at the Esplanade until March 3, from 11.30 am until 13.30 pm. Pay them a visit to make a donation or do it online: https://t.co/rV3pOaUFiQ
#Turkey #Syria
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"Several hundred people of Turkish or Syrian origin teach, learn and work at ETH Zurich," says Rector Günther Dissertori. ETH would like to express its solidarity with them and all those who have been affected by the catastrophic earthquake.
ethz.ch
On 6 February, an earthquake shook Turkey and Syria. An overview of fundraising appeals in aid of earthquake victims, and where affected members of the ETH community can find psychological support.
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Our latest work on devising metabolic engineering strategies using large-scale nonlinear kinetic models is now online on @biorxivpreprint: https://t.co/k7s1NQdquO Congratulations to Bharath (@bharathnarayana) Daniel (@realDRWeilandt) and Vassily (@Vassily_13)!
biorxiv.org
Increased availability of multi-omics data has facilitated the characterization of metabolic phenotypes of cellular organisms. However, devising genetic interventions that drive cellular organisms...
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Goodmorning :) Excited that our latest work, NICEgame, ( https://t.co/PEfq7DLO3O) just got published at @PNASNews!
pnas.org
Advances in medicine and biotechnology rely on a deep understanding of biological processes. Despite the increasingly available types and amounts o...
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Yoo our paper at @realLCSB and my art for the same is gracing the cover of @NatMachIntell August Issue! https://t.co/DX10jkliLE
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Good morning everyone :) Our recent work, REKINDLE, a deep learning pipeline to generate kinetic models of metabolism, just got published in @NatMachIntell! ( https://t.co/qZ9ryKyosP)
nature.com
Nature Machine Intelligence - Kinetic models of metabolism capture time-dependent behaviour of cellular states and provide valuable insights into cellular physiology, but, due to the lack of...
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Maria Masid, @AnastasiaSves, @oftadehomid, @aslisahin2205 and @EVayena really enjoyed the #LS2AM22, where they participated with 3 oral talks and 5 posters! Great job!
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Our latest work on optimal enzyme utilization is now online! In this study we present an evolutionary approach to enzyme kinetics, and introduce our computational framework to explore the catalytically optimal enzyme. Check out our preprint at
biorxiv.org
Understanding the dynamic responses of living cells upon genetic and environmental perturbations is crucial to decipher the metabolic functions of organisms. The rates of enzymatic reactions and...
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A big thank you to all the authors Asli @aslisahin2205, Daniel @realDRWeilandt and Vassily @Vassily_13!
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