Albert A. Antolin (he/him)
@antolin_aa
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PI & @SaludISCIII Miguel Servet Fellow @ProcureICO @idibell_cat @ICO_oncologia | Harnessing Systems Chemical Biology to better cancer treatment🏳️🌈👨👨👧✊🏾
Barcelona, Spain
Joined October 2013
Thrilled to share the 1st paper from my lab @chemicalbiology
https://t.co/3WF5Qae6zr Rucaparib and its major metabolite have different activity that becomes synergistic in prostate cancer lines & active in a #Parkinson model @ICR_London @ProcureICO @ICO_oncologia @idibell_cat A🧵
cell.com
Hu et al. comprehensively characterized the kinome profile of the major metabolite of rucaparib, M324. The study uncovers distinct kinase landscapes between rucaparib and M324 that translate into a...
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📢 I am hiring a postdoc in #AI-driven #DrugDiscovery! Join my lab in Barcelona. Focus: AI, #Cheminformatics, #StructureBasedDesign, #CellPainting, #ImmunoOncology 💡 DM me for more information #PostdocJobs #AI #DrugDesign #MachineLearning #Barcelona @EuroPhDNetwork @PostdocJobs
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25 anys del Genoma Humà🧬: l’IA i la química biològica irrompen per ajudar a desxifrar els secrets del genoma Un equip on participa l’IDIBELL lidera una iniciativa global🌐per entendre el genoma, i poder facilitar així el descobriment de fàrmacs 👉 Més: https://t.co/ko0fRhLJMn
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25 years of the Human Genome🧬: AI and biological chemistry break in to help decipher the secrets of the genome A team in which IDIBELL participates leads a global initiative @target2035 🌐 to understand the genome and thus facilitate drug discovery 👉 https://t.co/nmOb2YQHvE
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#RExPO25 Conference abstract: 'Leveraging cancer drug metabolites for precision drug repurposing' ➡ https://t.co/DIRV8KbT4p ✍️ Presented by @antolin_aa, Group Leader at @idibell_cat Join us in Barcelona or online on 24-26 September 💊 https://t.co/rrq15tnMmy
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20th #ASEICACongress 8-10OCT Bilbao(Spain) 5⃣0⃣0⃣Scientists 5⃣0⃣Speakers Meet the Expert and6⃣Sessions 👉Late Abstract Submission:1JUL 👉Early🐦16JUL Register to learn about the next-to-come in the diagnosis, imaging, monitoring and treatment of cancer ✍️ https://t.co/PJyAgsdnUj
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🌕L'investigador #IDIBELL Albert Antolin @antolin_aa va participar al programa Planeta Catalluna de @RadioGava, amb Maripaz Garcia, vicepresidenta de l'Ass Viladecans contra el càncer. 📻Van parlar del projecte de recerca per al qual treballa l'associació: https://t.co/GVvzAmgXOM
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Un plaer i un honor participar amb l’Associacio Viladecans Contra el Cancer en aquest projecte!
🚀Tret de sortida del projecte 2025 de l’Ass. Viladecans Contra el Càncer: el Dr. Albert Antolin (@antolin_aa) explica com fem recerca de nous fàrmacs amb eines d’Intel•ligència Artificial #IA 💻, i com volem aplicar aquesta estratègia a la #immunoteràpia del càncer colorectal.
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We are uniting experts in ML, computational chemistry, and drug discovery to get hands-on experience with AIRCHECK. Co-developed by SGC and @UHN, AIRCHECK is an open data platform designed to enhance predictive models in drug discovery. Register here: https://t.co/SPvAASEo5T
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#MAINFRAME is launching! This international, #OpenScience Network brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks for tackling real-world challenges in #DrugDiscovery. Join us:
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Join us!!
We just launched #MAINFRAME! This international, #OpenScience Network brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks for tackling real-world challenges in #DrugDiscovery. Join us: https://t.co/oAcLGeaK3d
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The ChEMBL-og: Here's a nice Christmas gift - ChEMBL 35 is out!
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8 billion. It's just a number. Today, our 3D tranche browser shows 8 billion* purchasable molecules in biologically relevant, docking-ready 3D formats. https://t.co/aI5PgHBsiP * Yes, yes, a wee bit of double counting. But, 8 billion!
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A 2024 update on @Chemical_probes highlights a significant expansion in the number of chemical probes and human protein targets, along with major improvements in expert review processes and user engagement. https://t.co/YfTclLB9qI
academic.oup.com
Abstract. The Chemical Probes Portal (www.chemicalprobes.org) is a free, public resource, based on expert-reviews, that supports the assessment, selection
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A fully open framework for DEL-ML hit discovery. We replace explicit DEL compound structures with ML-ready chemical fingerprints, enabling the broad scientific community to advance DEL-ML models and refine discovery methods. All data available on AIRCHECK. https://t.co/fg3lyssOpf
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Our latest work shows a reported #kinase inhibitor causes cytotoxicity by directly inhibiting MTs. We need more clarity on how #chemotherapy drugs work if we are to use them effectively to treat #cancer. Work led by fantastic clinical fellow @joshcoats
aacrjournals.org
Abstract. Elraglusib (9-ING-41) is an ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK3) with preclinical studies demonstrating broad activity against many tumor types. Promising early-...
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We are excited to announce publication of our latest BindingDB update paper! https://t.co/MUrB60kuvg
academic.oup.com
Abstract. BindingDB (bindingdb.org) is a public, web-accessible database of experimentally measured binding affinities between small molecules and proteins
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Happy to have contributed! Great increase in numbers and functionality, have a look!
🚨 New publication alert! 🚨 Our latest update on the Chemical Probes Portal is live! 🎉 📜 Read the paper: https://t.co/idifAiYU4t 🔍 Learn about our expanded content + improved functionality in the 2024 Nucleic Acids Research Database Issue. #ChemicalProbes #BiomedicalResearch
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The FDA has approved revumenib, the first menin inhibitor for relasped or refractory acute leukaemia with a KMT2A translocation https://t.co/KT5za3C5dO For more on menin inhibitors, here's a news story from earlier this year https://t.co/vbuLgfxqYF
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