I’m very happy to share that next month I will be joining WashU’s Dept of Orthopaedic Surgery to launch the Joint Crosstalk Lab @JointCrosstalk! Our major objective will be to understand cellular and molecular mechanisms in joint health, disease, and regeneration.

Last week, three of our undergrads presented their research at the WashU Fall Undergrad Research Symposium. Congratulations to Evan, Eesha, and Julia -- keep up the great work!

And second - our postdoc Tong Yang has been accepted into the WashU Center of Regenerative Medicine’s Distinguished Postdoctoral Scholars Program @wustlcrm - aimed at training tomorrow's leaders in regenerative medicine. Well done, Tong!! Go team!

Two pieces of exciting lab news today! First - our postbacc Izzy Smith received the Rita Levi-Montalcini Award for Best Poster Presentation at the recent WashU DevBio/Regenerative Med retreat @wustlcrm. Congrats Izzy!! https://t.co/fE2W4BhyFa

🧬⏰#CoverThursday: Chronogenetics Could Transform Arthritis Treatment! An image of a clock within a cell symbolizes the emerging field of #chronogenetics and a discovery from @Guilak_Lab that may bring us closer to timing medicine perfectly with the body’s natural rhythm 💫

The findings of this study indicate that physical activity directly adds to total energy expenditure, without evidence of constraint or compensation, in humans.

We're pleased to receive funding from the Rheumatology Research Foundation @RheumResearch to help us unravel the onset and persistence of synovial fibrosis in joint disease - so we can block it before it sets in!

I had tons of fun visiting @uiowa this week in Iowa City, interacting with colleagues and trainees in Immunology and Orthopaedics. Met wonderful people and was lucky to see their amazing facilities. Thanks especially to @KCyndari !

🪃 Boomerang Tour Pt. 4 — final leg of the trip attending the @icors_l conference in Adelaide. Great people and great research - got to share some of my work too. Thanks again to @ITSASBMB for bringing me down under. Until next time!

If you are at #ICORS2025🇦🇺🦘, I’d love to see you at my talk in the OA Molecular Biology session starting at 11:15a today, Oct 8th! I’m also super excited to be sharing the session with my friend and fellow UMich lab alum, @JointCrosstalk !

BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

One of the most-viewed PNAS articles in the last week is “Energy expenditure and obesity across the economic spectrum.” Explore the article here: https://t.co/CdV3dA6vCx For more trending articles, visit https://t.co/EEEVobYgkw.

🪃 Boomerang Tour Pt. 3 — it was such a treat to be back in Sydney at @UNSW. Reconnecting with old friends and colleagues - fond memories.

🪃 Boomerang Tour Pt. 2 — honored to receive the ASBMB Boomerang Award @ITSASBMB This award has given me the opportunity to ‘return’ to Australia to share my work and meet great people at various venues around the country - including the ASBMB2025 meeting here in Brisbane

🪃 Boomerang Tour Pt. 1 — had an amazing day at the @TRI_info @MaterResearch in Brisbane, sharing my work and talking science + collaboration. Lucky to also be joined by my sisters, Emily and Grace

"Only ~0.02%-3.1% of [a cell's] genome" is being transcribed at any given moment. Other interesting takeaways from this new paper: > If you pool together a bunch of cells of the SAME type (like primary immune cells from a mouse's spleen), and you measure the transcription for

Scientists present an advanced new technique for live-imaging regenerating limbs, shown here on a sand flea. https://t.co/KB3GOXgA2M

Today in @ScienceMagazine, we report a new DNA editing technology to seamlessly write massive changes into the right place in the human genome. The reason gene editing hasn't transformed human health is that current gene editing technologies like CRISPR are very limited. The

Thrilled to share our new paper in @ScienceMagazine ! We identify septal LYVE1⁺ adipose macrophages (sATMs) as niche signals that control stem cell fate, restrain beiging & shape obesity susceptibility. Team effort with @FGinhoux and collaborators. https://t.co/mVWJ451FPQ

It's a slightly bewildering stat that there'll be a projected 1 billion people with osteoarthritis in 2050 The therapies we use at the moment address symptoms but not the underlying pathology – this is a huge unmet need (and a massive opportunity for innovation)

Get to Know the Speaker: Dr. Alexander Knights On August 27 at 12 PM PT / 3 PM ET, join us for a special osteoarthritis webinar exploring the science behind how joints stay healthy—and what happens when things go wrong. Dr. Alexander Knights, from Washington University in St.