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Avi Roy Profile
Avi Roy

@agingroy

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Biomed Scientist in #longevity. Mentor & Investor in Health startups. Past CTO @BioVivaScience ,Researcher @CASMIORG ,Lead @oxfordscisoc @NewsInLongevity ,BGRF

Oxford, England
Joined May 2008
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@agingroy
Avi Roy
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@agingroy
Avi Roy
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RT @MariosGeorgakis: The modern cardiovascular drug development landscape has been largely shaped by human genetic studies. Emerging IL-6 t….
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@agingroy
Avi Roy
1 day
Breaking the benzo death trap: Startling data shows old studies claimed 4x death risk from anxiety meds, but meticulously controlled analysis of 1.25M patients found ZERO added mortality (HR=1.00, CI 0.96-1.04). Why the dramatic reversal? Bad methods create phantom demons.
@cremieuxrecueil
Crémieux
2 days
Benzodiazepines have been associated with tons of different causes of death, from cancer to car crashes. But why? Could it be that benzos hurt everything?. Doubtful. The reason seems to be that the studies were bad. With better methods, the risk elevation disappears.
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@agingroy
Avi Roy
3 days
Prime editing (an advanced form of gene editing that can precisely correct DNA errors) just restored immune function in chronic granulomatous disease (a rare immune disorder)—66% of immune cells that fight infections were working again by day 30, and inflammation was reversed.
@davidrliu
David R. Liu
4 days
Data from the second human treated with a prime edited medicine: a 56-year-old male with chronic granulotamous disease (CGD) had his bone marrow prime edited to insert the missing GT in NCF1, restoring NADPH oxidase function in neutrophils (DHR positivity) several fold beyond the
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@agingroy
Avi Roy
5 days
RT @MicrobiomDigest: This new preprint was designed so poorly that it provides absolutely no proof that mRNA vaccines caused cancer/other d….
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@agingroy
Avi Roy
5 days
RT @cremieuxrecueil: There's a widespread myth that zero-calorie sweeteners like aspartame spike your blood sugar and insulin levels. This….
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@agingroy
Avi Roy
6 days
RT @cremieuxrecueil: A massive new analysis found that rates of cognitive decline don't vary by education level. That is, though people wi….
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@agingroy
Avi Roy
8 days
This creates a dilemma: Hide AI use to maintain trust or be transparent and risk losing patients?. As AI transforms medicine, we must communicate its value without undermining the human connection essential to healthcare. ✅ How physicians can adopt AI while maintaining patient
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@agingroy
Avi Roy
8 days
The AI transparency paradox: Doctors disclosing AI use are perceived as LESS competent (-5.2%), trustworthy (-6.5%), and empathetic (-5.5%). A survey of 1,276 patients in @JAMANetwork shows transparency about #AI use reduces appointments by 11%, even for basic admin tasks.
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@agingroy
Avi Roy
10 days
RT @cremieuxrecueil: Cervical cancer is being defeated thanks to two things:. Pap smears and the Gardasil vaccine. HPV vaccination is so e….
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@agingroy
Avi Roy
10 days
RT @OurWorldInData: Life expectancy has increased dramatically in the last 150 years. How is life expectancy calculated, and what does it….
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@agingroy
Avi Roy
10 days
RT @shawnshenjx: I’m Shawn, founder of former researcher at Meta and CS PhD at University of Cambridge. Today we’….
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@agingroy
Avi Roy
13 days
Want to dive deeper? Here's your reading list:. 📊 Full study @BMCMedicine : What's your experience been? Let's discuss below 👇. #GLP1 #MedTwitter
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@agingroy
Avi Roy
13 days
What this means for YOU:.✅ Have realistic expectations.✅ Discuss long-term plans with your doctor.✅ Advocate for insurance coverage.✅ Don't blame yourself for biology. The science is clear: these medications work, but only while taking them. #Ozempic #WeightLoss #obesity
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@agingroy
Avi Roy
13 days
This isn't about willpower. Even patients who maintained diet & exercise saw regain. The implication? Obesity medication may need to be CHRONIC, like:.- Blood pressure meds.- Diabetes treatment.- Cholesterol drugs
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@agingroy
Avi Roy
13 days
Not all weight loss drugs are equal when it comes to rebound:. 🔴 GLP-1 drugs (#ozempic #wegovy ): 37% regain.🟡 Dual GLP-1/GIP drugs (#Mounjaro): 34% regain.🟢 Other AOMs (Orlistat): 25% regain. Why? It's about HOW they work on your brain and gut.
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@agingroy
Avi Roy
13 days
First surprise: You actually KEEP losing weight for 4 weeks after stopping! 📉. But then at week 8, something dramatic happens. Weight regain accelerates rapidly, with most people gaining 2.5 kg (5.5 lbs) by week 20.
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@agingroy
Avi Roy
13 days
New research reveals what REALLY happens when you stop #ozempic #wegovy . The results challenge everything we thought we knew about weight loss drugs. Here's what 11 studies covering 2,466 patients discovered.
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@agingroy
Avi Roy
20 days
RT @bbgoriginals: China's curing cancer faster and cheaper than anywhere else. But some worry they may be going too fast. More @business:….
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@agingroy
Avi Roy
20 days
📊 Want to dive deeper? Here's where the data comes from:. Primary Investigation: @business's exclusive analysis of @NorstellaCo's pharma intelligence database . Full article: What fascinates me most: This isn't government propaganda—it's Western.
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bloomberg.com
Chinese biotech's advance has been as ferocious as the nation's breakthrough efforts in AI and EVs, eclipsing the EU and catching up to the US
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@agingroy
Avi Roy
20 days
Remember when "Made in China" meant cheap knockoffs?. Now, China has more drugs in FDA/EMA expedited review than the entire European Union. These aren't generics—they're potential cures for cancers Keytruda can't touch. Your next life-saving medicine has a 50/50 chance of being
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