Yu Ye
@_yu_ye
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Proteostasis and dementia researcher; Coach @lab_ye; Senior Lecturer @ImperialBrains; ex-fellow @selwyn1882; Alumnus (he/him) @MRC_LMB|@stjohnscam
London, England
Joined July 2012
Join us for a truly interdisciplinary experience funded by @ARUKscientist working at @ImperialBrains! #PhD #biophysics
#bioengineering #Optics #microscopy
We're recruiting a PhD student to study protein aggregates in neurons using advanced fluorescence imaging techniques! Contact us if you have a background in biophysics/bioengineering/etc with prior experience in image analysis/coding. Find out more here:
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Join us and lead projects to determine proteostasis mechanisms in tauopathies and alpha-synucleinopathies funded by @ARUKscientist and @Eisai_SDGs, supported by @UKDRI and @ImperialBrains. A plus if you're into baking and public engagement activities!
🚨There's still time to apply for these two exciting postdoc roles in @lab_ye at Imperial! Details below, apply by 3 Nov⬇️
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We have some exciting news to share from the Ye Lab! The first PhD student of the Ye Lab, @liina_sirvio, recently passed her PhD viva at @imperialcollege! 🎉A big thanks to the excellent examiners Ed Tate and Catherine Lindon
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Applications for a computational postdoc in epigenetics in our group @ImperialBrains @UKDRI closes on Fri! Apply here: https://t.co/hjMzEjuyXY Who we are: https://t.co/KevC1WCzkT 🌈🥼💻🧬
lnkd.in
This link will take you to a page that’s not on LinkedIn
Looking for a computational postdoc in epigenetics and dementia? Join our team at @ImperialBrains @UKDRI_ECR! Details in the tweet below 💻🧠👩💼
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Come join us for fancy microscopy imaging in IPSC-neurons!
We have a postdoc position @ImperialBrains to work on degradation of tau aggregates for up to three years, funded by a generous major projects grant @ARUKscientist. Please recommend, spread the word and apply!
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Our wonderful postdoc @mikejmorten was featured in the @ImperialBrains staff blog! You can read it here:
blogs.imperial.ac.uk
As part of our Staff Profile series, we spoke to Dr Mike Morten, Research Associate in Dr Yu Ye's lab. Here, he tells us more about his research background and interests.
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Tuesday evening I’ll be interviewing my Cambridge colleague and friend @AtheneDonald about her new book. Join us in the @Selwyn1882 auditorium or online. https://t.co/PHfyKZfSGu
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In the college’s tradition, Fellows formed a guard of honour across Old Court for our late master Sir David Harrison after his funeral this afternoon. The service can be viewed here: https://t.co/nLOjmtN4S8
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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system:
nature.com
Nature Communications - Tau aggregates are associated with several neurodegenerative disorders. In this work, I. Saha and colleagues show that valosin-containing protein (VCP) recruited to Tau...
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Writing yet another research manuscript and I really want to cite this story in its finalised form. How is this not accepted yet!
biorxiv.org
Amyloid-like aggregates of the microtubule-associated protein Tau are associated with several neurodegenerative disorders including Alzheimer’s disease. The existence of cellular machinery for the...
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The other image I also really liked @lab_ye
A new study led by Dr Yu Ye (@lab_ye) found that small, aggregated proteins enter cells & cause distinct toxic effects in Parkinson’s & dementia with Lewy bodies Both involve the same protein (alpha-synuclein), but it behaves differently in each disease👉 https://t.co/BRW0MHMzgm
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Thanks for this generous support from the Uren foundation
A generous £7.5 million gift from the Michael Uren Foundation will drive forward experimental research into #Alzheimers disease at @imperialcollege @UKDRI
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Our latest paper is out now in @PNASNews! Quantitative super-resolution microscopy of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies Fantastic effort from @mikejmorten @liina_sirvio @yeyu_nj and collaborators! https://t.co/4LqRribxzT
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Thanks for highlighting our research article
New paper from @yeyu_nj @lab_ye & collaborators presents quantitative super-resolution imaging & analysis of alpha synuclein aggregates from #Parkinsons & dementia with Lewy bodies cases, revealing distinct toxicity profiles https://t.co/0Wk2kWhl2X
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In this review, the authors define protein condensation diseases as caused by aberrant liquid-like or solid-like states of proteins, and describe opportunities for therapeutic interventions. @VendruscoloLab
https://t.co/Fvg9OzV38T
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Happy postdoc appreciation week to our beloved @mikejmorten! A top notch scientist and enthusiastic fan of #GBBO #greatbritishpostdoc #GBPD
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We are recruiting @ImperialBrains a postdoc to study proteostasis and protein aggregation in neuronal models @UKDRI using IPSC and 3D microscopy techniques, with possibility for extension. Please get in touch and help rt! https://t.co/0zvRqASu85
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We are recruiting @ImperialBrains a postdoc to study proteasome activity on aggregates @UKDRI using advanced imaging and biochemical techniques, with possibility for extension. Please get in touch and help rt! https://t.co/uLXO06Koxh
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Cool stuff from John. Should we cancel our Nikon orders 🧐
Following the steps of our great predecessors, I am pleased to present a protocol for the NanoPro - a high-quality SMLM at a fraction of the price of available alternatives. The NanoPro is accompanied by many IKEA style illustrations to allow the broader community build it.
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Is anyone I know in London a member of Oxford & Cambridge Club to help out with a small favour?
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