_prashantbhat Profile Banner
Prashant Bhat Profile
Prashant Bhat

@_prashantbhat

Followers
888
Following
1K
Media
11
Statuses
260

Uncovering the functions of genome organization | M.D. @UCLAšŸ‘ØšŸ½ā€āš•ļø| Ph.D. '23 @mitchguttman @Caltech | Previously worked on #CRISPR @doudna_lab @UCBerkeley '14

Pasadena and Los Angeles, CA
Joined November 2017
Don't wanna be here? Send us removal request.
@_prashantbhat
Prashant Bhat
1 year
A long sought after hypothesis has been that organizing biomolecules in and around nuclear bodies is essential for functional RNA processing. We now provide direct evidence of this in @Nature for nuclear speckles and mRNA splicing. Check out this thread!.
@mitchguttman
Mitch Guttman
1 year
What are the functional roles of 3D genome organization? Our paper in @Nature led by @_prashantbhat demonstrates how dynamic 3D genome organization around nuclear speckles plays a crucial role in regulating mRNA splicing efficiency.
Tweet media one
14
27
154
@_prashantbhat
Prashant Bhat
4 days
RT @brangwynnelab: Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing du….
0
37
0
@_prashantbhat
Prashant Bhat
3 months
RT @yodai_takei: Excited to share our new paper out in @Nature revealing cell-type specific nuclear organization and its link to gene regul….
0
56
0
@_prashantbhat
Prashant Bhat
7 months
RT @mitchguttman: Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper….
0
190
0
@_prashantbhat
Prashant Bhat
8 months
Hi! I’ll be speaking at @harvardmed Department of Biomedical Informatics on December 5th about genome organization and splicing/speckles. Thank you to the organizers for the invite! Harvard/MIT/affiliate trainees can RSVP to attend with this link:.
Tweet media one
2
16
91
@_prashantbhat
Prashant Bhat
8 months
RT @bsabari: I am excited to share our review, published online today @NatRevMCB. Pilong Li, Gaofeng Pei, @Heankel_, and I review the curre….
0
43
0
@_prashantbhat
Prashant Bhat
8 months
Delighted to read this article by @TheScientistLLC featuring our work on nuclear speckles! Also features quotes from @mitchguttman and @belmont_andrew.
0
2
15
@_prashantbhat
Prashant Bhat
8 months
Elegant study by @ejkk0 & @daSpliceIsRight identifying 5'UTR intron sequences that enhance mRNA expression. Cool to see the integ. reporter + higher Dox leading to greater intron-med. enhancement. Suggests a feedback loop between transcription & splicing to boost gene expression!.
@ejkk0
Emma Kowal
8 months
My PhD work is live on bioRxiv today! :)
1
2
19
@_prashantbhat
Prashant Bhat
9 months
And a big and hearty congratulations to Gary Ruvkun, too!.
0
0
24
@_prashantbhat
Prashant Bhat
9 months
1st yr college (4/2011) Dr. Ambros visited Berkeley. His Cell 1993 paper was the 1st biology paper I ever read. After the talk, I asked for a picture; he looked around him when the organizer clarified, . "Victor, he is asking to take a picture *with* YOU!" 🄲. Congrats, Victor!🧬
Tweet media one
15
81
2K
@_prashantbhat
Prashant Bhat
9 months
RT @sofiquinodoz: Excited to share a new preprint!.(1)šŸ”¬The nucleolus is the most prominent nuclear condensate, with a fascinating multilaye….
0
111
0
@_prashantbhat
Prashant Bhat
9 months
RT @brangwynnelab: How do you turn a condensate inside-out? Congrats to @sofiquinodoz & @jiang_lifei & co-authors on amazing study from our….
0
41
0
@_prashantbhat
Prashant Bhat
9 months
RT @corcoran_lab: We are really excited to share this story! We discovered that a major function of the KSHV RNA, kaposin, is as an archite….
0
21
0
@_prashantbhat
Prashant Bhat
10 months
RT @UCSF: Cheer on.@UCSFDeptofEM’s Kishan Patel, MD, as he competes on @CBS #Survivor47 in the Fiji islands! This ER doctor thrives in high….
0
4
0
@_prashantbhat
Prashant Bhat
1 year
I’ve had the chance to interact with all of these amazingly bright and kind humans - congrats to all on their amazing PhDs from @lpachter lab! Go @Caltech!.
@lpachter
Lior Pachter
1 year
Proud of newly minted PhDs Tara Chari, @NeuroLuebbert, @tdilan4, and @LambdaMoses (PhD ā€˜23).
Tweet media one
0
0
11
@_prashantbhat
Prashant Bhat
1 year
RT @NatRevMCB: Now Online Splicing regulation through biomolecular condensates and membraneless organelles https://….
0
8
0
@_prashantbhat
Prashant Bhat
1 year
It was fun to present at my first @RNASociety meeting in Edinburgh! Thanks to the organizers for a great meeting and the audience for the engaging questions! #RNA24 . Want to chat about speckles and splicing in different cellular contexts, including disease processes? DM me!
Tweet media one
1
3
81
@_prashantbhat
Prashant Bhat
1 year
Thanks @philipcball for showcasing our work!.
0
0
6
@_prashantbhat
Prashant Bhat
1 year
RT @LaskerFDN: Proximity to nuclear speckles–areas dense in mRNA splicing regulators–determines mRNA splicing efficiency. Variation in dist….
0
5
0
@_prashantbhat
Prashant Bhat
2 years
RT @IdoAmitLab: ā€œFall in love with the problem, not the technologyā€.
0
22
0