Magdalena Zernicka-Goetz
@ZernickaGoetz
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Scientist @Cambridge & @Caltech trying to build life from stem cells to understand it better. The author of #TheDanceofLife. Warsaw/Cambridge/LA. Art @BBBPACK
Cambridge & Caltech
Joined May 2016
After building embryoids for 10 years, we succeeded in generating structures with brains, hearts, neural tubes, somites with a yolk sac. Both original submissions using two different approaches are on BioRxiv, to be published soon.
biorxiv.org
Embryo-like structures generated from stem cells can achieve varying developmental milestones, but none have been shown to progress through gastrulation, neurulation, and organogenesis.[1][1]–[7][2]...
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My book « Cells - The Illustrated Story of Life » is in New York. Thanks to « The Experiment » . Distributed by Norton in the book stores on december 2nd. Printed or digital copies can be preordered from the publisher or platforms. @theexperiment #artandscience #cellbiology
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FUTURES TRADERS: Get 40% off all evals, no activation fees, end-of-day drawdown in our live-market PRO+ accounts…and still daily PRO payouts!
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Such a great pleasure to visit Harvard today - thank you all for coming to my talk to hear news about our embryos and their models!
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Polar Bearings: Cells at the poles at different times in the early developing embryo have distinct behaviours breaking symmetry Image made with @LeicaMicro microsystems 📷 Adiyant Lamba & Meng Zhu et al @Cambridge_Uni in @eLife ➡️ https://t.co/PMtwr5KnjD with @DrJohnAnkers
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I’m excited to share a new postdoctoral opportunity in my lab to use chromosome engineering to study the consequences of chromosomal rearrangements in iPS cells. Check out the posting below and shoot me an email if you’re interested -
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There are little things you can do in sales that move the needle. Most overlook them because they seem insignificant. But they compound over time. This includes: Before the call - Join two minutes early - Have good lighting - Position your camera to show your chest up During
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@ZernickaGoetz His experiments inspired me to enter Ph.D. research on DNA replication and RNA transcription in X. laevis. Thank you Sir John for making basic research so exciting. Love this picture of the squamous epithelial cells keeping him company. 🔬
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John Gurdon, whom we lost today, was not only my mentor but a dear friend. We met 30 years ago in Cambridge. He believed in me more than I believed in myself. His generosity, boundless curiosity, and sense of adventure shaped my life as a scientist 🖤 He will be missed by many.
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John Gurdon as Traveller and as I like him most
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New protocol for growing mouse embryo-like models (blastoids) from stem cells aiding study of effects of environmental factors on embryo development 📷 Victoria Jorgensen, Min Bao & Sergi Junyent et al @ZernickaGoetz lab @Caltech in @Dev_Cell ➡️ https://t.co/t0pL8EKnwX
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Apply for the brand-new interdisciplinary PhD program in Dresden! Tony Hyman and I are seeking a student to study how condensates influence cellular reaction kinetics across different animal species. https://t.co/yrBbtBfweL
Accepting applications from highly motivated Masters degree holders with prior research experience to take on interdisciplinary thesis projects in Dresden on the physical properties & biological functions of Biomolecular Condensates. Apply before 24.10.: https://t.co/8pWxOebO16
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Online now: Efficient stem cell-derived mouse embryo models for environmental studies
cell.com
Jorgensen, Bao, Junyent, et al. aggregate ESCs, TSCs, and PE-fated inducible GATA4-ESCs to build iGATA4-blastoids: robust and highly efficient stem cell models of the mouse blastocyst. iGATA4-blast...
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Warmest congratulations & thanks to brilliant member of our team @Caltech Wenqi Hu, collaborator @Roser Vento (not on X) & HDBR for a fantastic journey in bringing this unique resource. We hope it will be valuable as a reference point to build more powerful stem cell models
Atlas of amnion development during the first trimester of human pregnancy @NatureCellBio @ZernickaGoetz
https://t.co/LrxcJfe1wk
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@SocDevBio Another example of what a whole embryo of a model/ research animal provides that in silico and in vitro conditions cannot offer.
🧠✨ E14 mouse embryo lighting up with neural progenitors! Nestin (⚪️), p73 (🟢), and Tbr2 (🔴) mark distinct progenitor populations shaping the nervous system. @VishalLolam is investigating how their balance is disrupted in neurodevelopmental disorders. #FluorescenceFriday
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While I’m a big fan of new technologies that help us study human biology…there’s still no replacement for animal research! I wrote an article outlining this in @GENbio
https://t.co/CGXeaMs7Fa
genengnews.com
The portrayal of uncaring scientists without any thought for the animals being used in their research is far from the truth.
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I saw it firsthand at the #Lindau2025 Nobel Laureates meeting--international young scientists welcomed and recruited in Germany and elsewhere. Some of the very best are leaving, and many of the best will no longer come. https://t.co/5TtqpRIYIx
wsj.com
Research-funding cuts and immigration changes threaten some of America’s economic advantages.
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Is you support animal research, watch the video and comment!
https://t.co/q9x70xVVLs Please watch video and post a comment in support of use of animal models. They are seeking our input and if we don’t provide it then they will simply say well we didn’t hear anything
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Dear all, Please comment on the importance of model organisms research
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My son sang last night. It’s hard to believe that before he was born, tests suggested he might not survive or thrive. I’m endlessly grateful for the path I chose. To study human embryos is not to lessen the mystery of life—but to honour it, and to save it when we can.
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In this conference we couldn't care less where you published your story because 1. we only care if it's interesting and good and 2. participants will discuss unpublished work
Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres. #theconferencetoendallconferences Register now:
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This is exactly right and we'll experiment with this format in Woodstock Night Science in June! "Day science" prepared talks will be followed up on with "Night Science" explorations. Join us! #theconferencetoendallconferences
I feel like the conference talk format has gotten so stale, even for those who are good at it. How can we switch it up? One idea is an "interview" style, where after a 5 minute presentation, an interviewer who has read the paper engages in a structured conversation. Thoughts?
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We felt it during our lab meeting so many miles away, in Pasadena
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When Tech Week’s not happening, we get a little nostalgic around here. This week’s an exception. News coming soon.
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