Yangfei Xiang
@Yangfei_Lab
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Asst Prof at ShanghaiTech University | Stem cells, brain #organoids, brain disorders.
Shanghai, China
Joined October 2013
Glad to present our website! Please check https://t.co/rXGSZmtJfc. Thanks to all🤝🌹
yxlab.org
Xiang lab at Shanghaitech, led by Yangfei Xiang, is working on human brain organoids and their applications. 上海科技大学向阳飞实验室-大脑类器官技术与应用
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🚨 New method alert! @ShanghaiTechUni researchers report a method to differentiate #hPSCs into 3D #NeuralOrganoids that resemble peripheral sympathetic ganglia, producing both neurons and glial cells of the ganglia in a self-organized manner: https://t.co/WsMWKN2v47
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Online Now! Human PSC-derived organoids model sympathetic ganglion development and its functional crosstalk with the heart https://t.co/kj8tcCM5FL
#stemcells
cell.com
Sympathetic ganglia control vital body functions, yet their modeling is challenging. Xiang and colleagues developed hPSC-derived organoids that recapitulate the sympathetic ganglia and their functi...
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3/4 These models can facilitate future research into human sympathetic ganglia and cardiac innervation, encompassing studies on regulatory factors, risk factors, and potential interventions.
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2/4 We also developed a system to reconstruct functional connections between the human sympathetic ganglion and the heart, and found that inter-tissue crosstalk promote the development of both human sympathetic and cardiac tissues.
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1/4 In this study, we achieved self-organized and enriched production of human sympathetic lineages in 3D culture. Sympathetic neurons and satellite glial cells were generated robustly and exhibited long-term structural and functional development.
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We are pleased to share our latest progress in human neural organoids, recently published in Cell Stem Cell @CellStemCell.
cell.com
Sympathetic ganglia control vital body functions, yet their modeling is challenging. Xiang and colleagues developed hPSC-derived organoids that recapitulate the sympathetic ganglia and their functi...
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Looking forward to sharing our latest research progress at the conference.
Free online registration for Cell and gene therapies for neurological conditions: From bench to bedside | December 10-11, 2025 https://t.co/st0lN0PNjY
@MedCellPress @CellRepMed @NeuroCellPress @CellReports
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ShanghaiTech University scientists describe the generation of 3D, neuromusculoskeletal tri-tissue #organoids from human #pluripotent stem cells through a co-development strategy. 🧫 🔗 Get the full story in @CellStemCell! https://t.co/yE1vpIjX30
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Online Now! Generation of self-organized neuromusculoskeletal tri-tissue organoids from human pluripotent stem cells https://t.co/aAzJmmuINm
#stemcells
cell.com
Modeling the neuromusculoskeletal (NMS) axis with organoids is challenging. Xiang and colleagues developed hPSCs-derived NNMS organoids (hNMSOs) with co-development, self-organization, and functional...
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Congratulations to my three PhD students (Yin Yao, Zhou Wei, and Zhu Jinkui). Thanks to all who have helped us in this process.
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There is no need to separately differentiate and co-culture different lineages, which will facilitate future applications.
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Excited to share that our recent research has been published in @CellStemCell. This study has achieved simultaneous production and self-organized development of human neural, muscular and skeletal tissues within individual organoids.
cell.com
Modeling the neuromusculoskeletal (NMS) axis with organoids is challenging. Xiang and colleagues developed hPSCs-derived NNMS organoids (hNMSOs) with co-development, self-organization, and functional...
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I’m glad to share that our recent study on human SpV organoids has been featured on the cover of the October issue of @CellStemCell!
Our October issue is live! The cover features a story from @Yangfei_Lab making human medullary spinal trigeminal nucleus organoids, the information hub of the brain. Other highlights include a Review from @Marta_Shahbazi @vincentpasque on human development and embryo models,
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Wei Pang, Jinkui Zhu, and a team in the @Yangfei_Lab developed region-specific brain #organoids that recapitulate the development of the spinal trigeminal nucleus! 📌@CellStemCell: https://t.co/i5gDAZDEA4 🎧: https://t.co/lYVIeN5s58
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Online Now! Generation of human region-specific brain organoids with medullary spinal trigeminal nuclei https://t.co/tbkekZwen1
#stemcells
cell.com
Generating brain organoids with nucleus-specific identities is challenging. Xiang and colleagues report a method for generating human region-specific brain organoids that recapitulate the medullary...
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Excited to share our latest research published in @CellStemCell . In this study, we generated human brain organoids resembling the medullary spinal trigeminal nucleus and developed a model to study the trigeminothalamic connections.
cell.com
Generating brain organoids with nucleus-specific identities is challenging. Xiang and colleagues report a method for generating human region-specific brain organoids that recapitulate the medullary...
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Great to attend #CSOrganoids2024 in person to talk about our most recent research progress. Thanks @CellSymposia @CellStemCell @Dev_Cell for organizing this fantastic event. It’s always a honor to meet and chat with great scientists in the field.
Still time to register and discuss “building human neural #organoids to model the brain and beyond” w/ speaker Yangfei Xiang, ShanghaiTech University, China @CellSymposia #CSOrganoids2024
https://t.co/6hY84L2FOf
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Glad to share our latest work on ventralized human thalamic organoids @CellStemCell. Congrats to @Kiral_Ridvan @bilal_cakirr @lab_tanaka @Inhyun_P and all who supported this.
cell.com
Generation of organoid models for subregions of the human brain is challenging. Park and colleagues report a method to generate ventralized thalamic organoids, which recapitulate molecular and...
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Online Now! Generation of ventralized human thalamic organoids with thalamic reticular nucleus https://t.co/3i8yw5ypv6
#stemcells
cell.com
Generation of organoid models for subregions of the human brain is challenging. Park and colleagues report a method to generate ventralized thalamic organoids, which recapitulate molecular and...
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Congrats to all👍
Excellent work by @Kiral_Ridvan, @bilal_cakirr, @Yangfei_Lab, and @lab_tanaka is finally out at @CellStemCell to generate ventrally fated human thalamic organoids. https://t.co/2Hd5uTU0Vo
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