Yoshiaki Tanaka lab@UdeM
@lab_tanaka
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We study brain tumor, tissue development and other human diseases using in vitro & in silico approaches. #umontreal, #CRHMR, #organoids, #bioinformatics, #AI
CRHMR, University of Montreal
Joined December 2020
ポスドク時代に関わった研究がCell Reportsにpublishされました。電子レンジや携帯電話から出るradiofrequencyが脳に与える影響を調べた研究です。
cell.com
Cakir et al. show that radiofrequency exposure disrupts radial glial differentiation and induces autism-related gene expression in human cortical organoids. BET protein dysregulation underlies these...
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Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development: Cell Reports
cell.com
Cakir et al. show that radiofrequency exposure disrupts radial glial differentiation and induces autism-related gene expression in human cortical organoids. BET protein dysregulation underlies these...
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Analyses of one of the world’s largest protein datasets offer new insights into the biological underpinnings of major neurodegenerative diseases, according to research from the Global Neurodegeneration Proteomics Consortium in @NatureMedicine and @NatureAging.
nature.com
The Global Neurodegeneration Proteomics Consortium is a multi-national database that aims to leverage proteomics and clinical data to understand and improve ...
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今号のNature 誌に、脳オルガノイドを改良する試みを紹介する記事が出ています。私たちの「コネクトイド」もより良いモデルを作るための手法としてハイライトしてもらっています。とても読みやすくよくまとまっていますので、ぜひ読んでみてください。 https://t.co/2caQRJK6i7
nature.com
Nature - With organoids, assembloids and a growing toolkit of bioengineering tricks, scientists are stitching together models of the developing human brain — and pushing the limits of realism and...
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(Dr. Tanaka write an article in Japanese) 先日Genome Res誌に発表した論文の紹介記事を実験医学で書かせていただきました。近年急速に発展しているAIをシングルセル解析にどのようにしてフィットさせたのか解説しています。 https://t.co/4RjqZ8i5yX
yodosha.co.jp
特集1：いかにして生体組織は自律的に組み上がるのか？ 細胞集団のふるまい・機能を自在にデザインし，自己組織化の謎と人工組織の創出に挑む／特集2：管理者権限がなくても大丈夫．共通計算機でも新たな解析ツールを気軽に試せる方法を手取り足取り伝授します．
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📣 We are hiring! Join Yoshiji Lab at McGill University Dept of Human Genetics in Montreal, Canada! https://t.co/lIoDBcTnA6 ✅Fully Funded Positions • 2 MSc Students • 1 PhD Student • 1 Postdoc ✅Goal: Using human genetics and multi-omics for drug target discovery and
📣Excited to share our paper in @NatureGenet! https://t.co/ppAX1dqKZg Do plasma proteins mediate obesity’s effect on CAD risk? →Using two-step proteome-wide MR, domain-aware MR, epigenomics & scRNA-seq, we prioritized endotrophin as a mediator & potential therapeutic target A
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Je suis heureux de partager notre nouvel article publié dans Genome Research. Ce projet propose une nouvelle approche d'apprentissage profond pour déduire le niveau de progression de la maladie des cellules individuelles dans scRNA-seq.
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I am happy to share our new article published in Genome Research. This project proposed a new deep learning approach to infer disease progression level of individual cells in scRNA-seq.
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ShanghaiTech University scientists describe the generation of 3D, neuromusculoskeletal tri-tissue #organoids from human #pluripotent stem cells through a co-development strategy. 🧫 🔗 Get the full story in @CellStemCell! https://t.co/yE1vpIjX30
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I'm glad to see @Mila_Quebec properly mentioned in the Japanese article.
AI研究力、シンガポールや韓国躍進 アメリカ帰りの人材活躍 https://t.co/Hh2GpnNfoy AIの国際学会の論文の著者数を機関別にみると、アジア勢の存在感が鮮明に。2020年に29位だったシンガポール国立大学は12位まで上昇しています。
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iPS細胞から作った「脳オルガノイド」をコンピューターにできるのか ―― ソフトバンクと東大が実験結果を発表(ケータイ Watch) #Yahooニュース https://t.co/NFJopPkUFw
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プレプリント（査読前論文原稿）が出ました！ オルガノイドをつなげることが機能性の向上に必要であることを見つけました。 Our preprint is out. We found that connecting organoids is critical for enhancing their functionality. https://t.co/KslAjMntn1
biorxiv.org
Neural organoids form complex networks but lack external stimuli and hierarchical structures crucial for refining functional microcircuits. In this study, we modeled the hierarchical and modular...
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Dr Tanaka a reçu le prix Maud Menten du nouveau chercheur principal de l'Institut de génétique des IRSC.
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Dr. Tanaka received Maud Menten New Principal Investigator Prize by the CIHR Institute of Genetics.
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Nous recherchons un étudiant postdoctoral ou diplômé très motivé.
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We are looking for highly-motivated a postdoc or graduate student.
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Dr Tanaka a été récompensé en tant que futur leader de la recherche sur le cerveau au Canada. https://t.co/FR4hc3cQ4q
braincanada.ca
Les bourses de formation à la recherche visent à favoriser la compréhension des cancers du cerveau et le développement de nouveaux traitements novateurs
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Dr. Tanaka was awarded as Future Leaders in Canadian Brain Research.
braincanada.ca
Brain Canada supports training awards aim to improve understanding of brain cancers and advance development of innovative new treatments
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Nous recherchons un étudiant postdoctoral ou diplômé très motivé.
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