Westermann lab
@WestermannLab
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Host-pathogen-microbiota interactions lab @Helmholtz_HIRI @Uni_WUE . We love everything RNA! Tweets by Alex (-AW) or other lab members (-Lab).
Würzburg, Germany
Joined July 2020
Is it anything Hfq-like (RNA chaperone)? Or similar to CsrA (global translation modulator)? We don't know yet. But as it stands, Bacteroidota RRM proteins appear as excellent candidates to map post-transcriptional networks in gut microbiota species.
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RT @MoualiYoussef: Happy to share our work, now out in @cellhostmicrobe!. We investigated the human gut commensal Segatella copri (former P….
cell.com
El Mouali et al. characterized the RNA landscape of the human gut-residing bacteria Segatella copri using in vitro and gut-derived samples. They identified a small RNA regulator essential for gut...
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RT @abaumler: We are all living in a bubble that deprives us of experiences needed to understand the true magnitude of the threat posed by….
science.org
This month, the United Nations (UN) General Assembly will convene its second High-Level Meeting on antimicrobial resistance, urging UN member states to take decisive action against this growing...
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RT @MeetingRna: 1/2.Please mark your calendars for the 8th Conference on Regulating with RNA in Bacteria and Archaea! The meeting will be h….
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RT @LBarquist: We determined gene essentiality in 13 Enterobacteriaceae including E. coli, Salmonella and Klebsiella strains, and find ~1/3….
journals.asm.org
The essential genome, that is the set of genes absolutely required to sustain life, is a core concept in genetics. Essential genes in bacteria serve as drug targets, put constraints on the engineer...
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Last month, Gianluca Prezza (@prezzag) from the lab very successfully defended his PhD. 🎓Congratulations, Gianluca!!!.While we will sorely miss you, we wish you the best of luck for your future endeavors with @ProfTomEllis. (-AW)
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RT @biorxiv_molbio: A small RNA derived from the 5' end of the IS200 tnpA transcript regulates multiple virulence pathways in Salmonella Ty….
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RT @yanjiechao: Happy to share the results of last 5 years' work in #Klebsiella. By performing iRIL-seq in hypervirulent K. pneumoniae (HvK….
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RT @OKurzai: @lab_rudel introduces the basic concept of @CRC_DECIDE at #DGHMVAAM2024 after two great keynotes by @AndreasPeschel1 and….
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RT @LBarquist: Interested in RNA-targeting antisense technologies to manipulate and kill bacteria? Come join us in Würzburg this September….
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RT @biorxiv_micrbio: The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization https://t….
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RT @papenfortlab: Check out our newest manuscript published today in Cell Host & Microbe
cell.com
Activation of the lysogenic phage VP882 triggers intricate transcriptomic shifts in V. cholerae. Sprenger et al. reveal that phage activation promotes sRNA base pairing with host or phage transcripts...
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RT @NWenner: If you ever wondered why your favorite enteric bacterium does not grow well on a particular carbon source, despite carrying al….
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RT @LBarquist: Very excited to finally see our study of global RNA stability in Salmonella out today in .@PNASnews, where we use Bayesian s….
pnas.org
RNA decay is a crucial mechanism for regulating gene expression in response to environmental stresses. In bacteria, RNA-binding proteins (RBPs) are...
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RT @lab_maier: Over the moon that the DFG is establishing a priority programme to elucidate gene functions in the human gut microbiome. I a….
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5/5: Sharing our discoveries with the world! 🌍 Our data, now publicly accessible via Theta-Base (, serve as a valuable resource for the microbiome research community, fueling further exploration into the fascinating world of gut bacteria.
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4/5: What's MasB up to? 🤔 Using MS2 affinity purification and RNA-seq, we identify MasB's target and explore its impact on bacterial phenotypes. #MasB #GeneRegulation
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3/5: Small RNAs (sRNAs) play big roles! 🎵 By expanding the annotation of sRNAs and integrating transcriptomic & functional genomics data, we pinpoint conditionally important ones like MasB, crucial for regulating tetracycline tolerance. #sRNAs #AntibioticResistance
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