Wael Awad
@WaelAwadMoh
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ARC Australian DECRA Fellow Group leader | Metabolite Processing and Presentation @MonashUni Structural immunologist
Melbourne
Joined April 2018
Finally, published @JExpMed after a decade of work. Through multidisciplinary approaches, we found that components of #cigarrete & #vaping smoke (CS) modulate #MR1- #MAIT cells axis in the lung with a major implication for COPD, the third leading cause of death worldwide.See š§µ.
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Mitochondria produce nucleobase ligands for T cells. Our recent paper was published today in PNAS. @Jamie_Rossjohn @Jamie_Rossjohn.Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells.
pnas.org
Mitochondria coordinate several metabolic pathways, producing metabolites that influence the immune response in various ways. It remains unclear wh...
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Our recent review on MR1/MAIT axis. Molecular Insights Into MR1āMediated T Cell Immunity: Lessons Learned and Unanswered Questions .@Jamie_Rossjohn @Jamie_Rossjohn @Monash_FMNHS
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RT @LabWaggoner: Commentary @Cancer_Cell @Schumacher_lab.Learning the language of TĀ cell receptors through large-scale screening. https://t.ā¦.
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RT @ELeeansyah: Happy to share our #MAIT lab @TsinghuaSIGS latest review on our favourite cell homing in intestinal homeostasis and inflammā¦.
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RT @SandbergLabKI: Happy to share our latest findings out today in @PNASNews by @C_Boulouis showing how human mucosal-associated invariantā¦.
pnas.org
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that mediate rapid antimicrobial immune responses to antigens derived from m...
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RT @JExpMed: .@WaelAwadMoh, Mayal, Xu, @HansbroResearch @Jamie_Rossjohn et al. @MonashUni show that cigarette smoke can impair MAIT cell fuā¦.
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RT @STITCHESMed: Cigarette smoke components harm MAIT cell function, increasing infection risk and exacerbating diseases like chronic obstrā¦.
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RT @JExpMed: Cigarette smoke components modulate the MR1āMAIT axis, say Wael Awad (@WaelAwadMoh), Jemma Mayall, Weijun Xu, Jamie Rossjohn (ā¦.
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Cigarette Smoke Impairs Lung Immune Cells, Elevates Infection Risk via @karmactivealive.
karmactive.com
"New study reveals how chemicals in cigarette smoke impair lung immune cells, heightening infection risk. Learn the implications for smokers and those exposed to second-hand smoke."
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How Cigarette Smoke Cripples Key Lung Defenders
medindia.net
Cigarette smoke damages key lung defenses, weakening the bodyās ability to fight infections and leading to respiratory diseases and chronic lung conditions.
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Cigarette smoke alters immune cell function in the lungs.
news-medical.net
Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of...
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RT @WHOWPRO: Have you been thinking about trying vapes or e-cigarettes? Think again!. Most e-cigarettes contain nicotine and other harmfulā¦.
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RT @JExpMed: #PressRelease š° Australian researchers have discovered that multiple chemicals found in cigarette smoke & e-cigarettes alter tā¦.
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RT @JExpMed: .@WaelAwadMoh, Mayal, Xu, @HansbroResearch @Jamie_Rossjohn et al. @MonashUni show that cigarette smoke contains a diverse mixā¦.
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My interview with the Australian . Researchers find clue to how smoke causes disease.via .@australian
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RT @LabWaggoner: Cigarette smoke chemicals bind MR1 and modulate MAIT cell function in the lung through diverse mechanisms, impacting theirā¦.
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RT @RockUPress: In @JExpMed, @WaelAwadMoh, Mayal, Xu, @HansbroResearch @Jamie_Rossjohn et al show that cigarette smoke contains a diverse mā¦.
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