Joost Snijder
@joostsnijder
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a sort of scientist. viruses and antibodies. structure and biophysics. mass spec and cryoEM. assistant professor @UtrechtUni @ICI_NL | voorzitter SP Culemborg
Utrecht, The Netherlands
Joined December 2015
The Brixen Proteomics Summer School is back! Speaker list is already looking strong!
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Structures of the fusion glycoprotein from respiratory syncytial virus (RSV) were used to engineer effective vaccines to fight viral infection More at PDB-101:
pdb101.rcsb.org
Structures of the fusion glycoprotein from respiratory syncytial virus (RSV) were used to engineer effective vaccines to fight viral infection.
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โSomni,โ our most ambitious album to date, made possible by a team of over one hundred musicians, engineers, videographers, lighting specialists, and production crew, is finally out worldwide. https://t.co/rkU8YCxD0O
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A groundbreaking paper by @younis_sh1 et al. @stanfordimmuno provides an answer to the long-standing question about how EBV infections are linked to lupus. A short thread to explain the key findings. (1/) https://t.co/dUpz19IjEv
science.org
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
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Delighted to share the peer-reviewed version of our article describing a prefusion-stabilized MARV GP vaccine immunogen and a best-in-class MARV neutralizing and protective antibody! Led by Amin Addetia with @VirBiotech
@HHMINEWS
https://t.co/SI78iXWkef
nature.com
Nature - Potent neutralization of Marburg virus by a vaccine-elicited antibody
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This recent article in @JVirology is a treat for researchers with interest in #picornaviruses. The team @mihnea_bostina Lab reconstructed essentially all intermediate states of uncoating of the oncolytic Seneca Valley Virus from only a few hundred electron micrographs.
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Thrilled, and admittedly relieved, to see this major investment in Dutch #cryoEM become reality! ๐ณ๐ฑ๐ฌ Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! https://t.co/PhbGCUvxk5
uu.nl
A major new national facility for electron microscopy, called EMPower, has been awarded to a consortium of Dutch universities and medical centers.
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Hot off the presses and 5 years in the making โ our first step toward building a synthetic carboxysome is out in @NatureComms An amazing collab between @SydneyChemistry @ARC_CoESB and @ourANU:
nature.com
Nature Communications - Installing algal pyrenoids or cyanobacterial carboxysomes into plants to enhance photosynthetic efficiency remains a formidable challenge. Here, the authors report the...
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โง ๐๐ฆ๐ญ๐ญ๐ฐ ๐๐ด๐ฆ๐ณ๐ด! ๐๐ฆ ๐ข๐ณ๐ฆ ๐ค๐ฐ๐ฎ๐ช๐ฏ๐จ ๐ฃ๐ข๐ค๐ฌ ๐ง๐ฐ๐ณ ๐ข ๐ง๐ฆ๐ธ ๐ด๐ฉ๐ฐ๐ธ๐ด ๐ช๐ฏ ๐๐ถ๐ณ๐ฐ๐ฑ๐ฆ ๐ช๐ฏ ๐๐ฆ๐ค๐ฆ๐ฎ๐ฃ๐ฆ๐ณ, ๐ด๐ต๐ฐ๐ฌ๐ฆ๐ฅ ๐ต๐ฐ ๐ฃ๐ฆ ๐ฑ๐ญ๐ข๐บ๐ช๐ฏ๐จ ๐ช๐ฏ ๐ต๐ฉ๐ฆ ๐๐ฏ๐ช๐ต๐ฆ๐ฅ ๐๐ช๐ฏ๐จ๐ฅ๐ฐ๐ฎ ๐ง๐ฐ๐ณ ๐ต๐ฉ๐ฆ ๐ง๐ช๐ณ๐ด๐ต ๐ต๐ช๐ฎ๐ฆ! ๐ด๐ฆ๐ฆ ๐บ๐ฐ๐ถ ๐ด๐ฐ๐ฐ๐ฏ โง ๐ณ๐ฑ๐ฌ๐ง๐ซ๐ท
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New preprint! "An engineered closed-shell, two-component, 480-subunit nucleocapsid" https://t.co/MFyHx78TS3 Thanks to all co-authors! @Mik_Levasseur @AngelaSteinauer @stetter19
biorxiv.org
Self-assembling protein cages are powerful nanoscale containers for biotechnology and medical applications. Two-component systems are especially attractive due to their potential for functional...
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Happy to share that our paper on the PlPVC1 eCIS is out in @NatureComms ๐ฅณ Congratulations to first author Leyre Marรญn-Arraiza and all co-authors! #cryoEM @cryoEM_Papers @UCPH_CPR
nature.com
Nature Communications - Marรญn-Arraiza and colleagues report the cryo-EM structures of an extracellular contractile injection system from Photorhabdus luminescens in extended and contracted...
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Welcome to flu season. Influenza Neuraminidase is an important target for influenza drugs More at PDB-101: https://t.co/IjJXt5QXI4
pdb101.rcsb.org
Neuraminidase is an important target for influenza drugs
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Evolution of Ab cross-reactivity to influenza H5N1 NA: New work isolates & characterizes protective antibody against influenza neuraminidase that acquires cross-reactivity to avian H5N1 as a byproduct of affinity maturation against human H3N2 @wchnicholas
https://t.co/RGeirbO2ER
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Atypical viral latency๐ฆ โฑ๏ธ has been found for Ebola virus (known to only induce acute infection in human), again! Our latest preprint on viral condensate prolonging residential RNA half-life may provide a clue. See ๐ https://t.co/tcHIgNNqK0
"Instead of clustering with more recent outbreaks, a pathogen assumed to evolve steadily appears, in part, unchanged for half a century." New letterโEbola virus in Kasai revives 50-year-old questions on viral latency
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