Stephan Hammer
@Stephan_Hammer
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biocatalysis, organic synthesis & directed evolution @unibielefeld @CeBiTec
Joined October 2016
Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry. 🙏 RETWEET (We want to recruit internationally) Organic chemistry meets #DirectedEvolution Highly interdisciplinary & passionate research group https://t.co/YthVJyynS2
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Really enjoying #Repartzymes Repurposed and Artificial Enzymes meeting organized by #TomWard of Uni. Basel. Many former group members are here! https://t.co/P3GoQqgUce
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This is a fantastic meeting!
We are delighted to announce that registration for the 5th NextGenBiocat in Milan on 8-9 May 2025 is now open. NextGenBiocat is organised by and at early career researchers in bioctalysis, to share their research, and network with peers.
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Big congratulations to Sebastian Gergel for winning the biocatalysis award of the German Chemical Society @GDCh_aktuell
Die GDCh zeichnet Sebastian Gergel, EnginZyme AB, Solna, Schweden, für seine Dissertation zu Protein Engineering und dem Design neuer Enzyme mit dem GDCh-Preis für Biokatalyse aus: https://t.co/yNgOQ8mxbh
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Lineup: @francesarnold Bornscheuer @rebeccambuller @FasanLab @GreenGroupMIB Hauer @HysterLab @xiongyih @huangx513 @JCLewisLab @GPoelarends @RoelfesGroup Reetz @yang2biocat @HuiminZhaoLab and many others
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New Age of Biocatalysis by Generic Activation Modes. The field can expect rapid growth in the near future. Enzyme Engineering + Generic Activation Modes Many new catalytic transformations | JACS Au https://t.co/RJTzz2jyoE
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#OnTheCover Front Cover: Efficient Transferase Engineering for SAM Analog Synthesis from Iodoalkanes (ChemBioChem 10/2024) (S. C. Hammer et al.) @Stephan_Hammer
https://t.co/OVDZqFpT5t
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Molecular Basis for Chemoselectivity Control in Oxidations of Internal Aryl-Alkenes Catalyzed by Laboratory Evolved P450s (S. C. Hammer, M. Garcia-Borras et al.) @Stephan_Hammer, @MarcGBQ, @IQCCUdG, @UdGRecerca #openaccess
chemistry-europe.onlinelibrary.wiley.com
Computational modelling involving density functional theory (DFT) calculations, molecular dynamics (MD) simulations, and hybrid quantum mechanics / molecular mechanics (QM/MM) calculations, are used...
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🙏 for the highlight! @ChemEurope
Our Pick of the Week, published #OpenAccess in @ChemBioChem by @MarcGBQ, @KaiSchuelke, @Stephan_Hammer and team at @unibielefeld: "Efficient Transferase Engineering for SAM Analog Synthesis from Iodoalkanes" https://t.co/CDc2C9XMi6
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Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry. Organic chemistry meets #DirectedEvolution Highly interdisciplinary & passionate research group 🙏RETWEET (We want to recruit internationally) https://t.co/xol9YRph9u
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Efficient Access to S-Adenosylmethionine Analogs: Enzymatic alkylation of S-adenosyl-L-homocysteine using iodoalkanes https://t.co/uLggyaSAIs
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Orders of magnitude higher activity, for multiple substrate, in a single enzyme engineering step? Efficient transferase engineering for SAM analog synthesis ... towards selective alkylation with engineered enzymes @KaiSchuelke @MarcGBQ #FOR5596
https://t.co/zaxejCD36d
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Controlling carbocation rearrangements with a catalyst can be very challenging. Find out now in @angew_chem how engineered enzymes control the acid-catalyzed isomerization of pinene. https://t.co/OqM7NsbwqS
onlinelibrary.wiley.com
Carbocation-based rearrangements are vital for terpene versatility. AacSHC triterpene cyclase from Alicyclobacillus acidocaldarius acted as a promiscuous catalyst for multiple monoterpene rearrange...
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Great collection! Our article was collaborative work with @Stephan_Hammer and @EnzymeNicoCorn.
Interested in biocatalysis? Check out this cross-RSC collection covering work from across biocatalysis research, including work by ChemComm authors @RentmeisterLab, @JCLewisLab, @Lipshutz_group & many more! Read the full collection here 🔗 https://t.co/n7OHQ2ibs6
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Our research unit "Exploiting the potential of S-adenosylmethionine-dependent enzyme chemistry" #FOR5596 led by @andexerlab will be funded by @dfg_public. Looking forward to work with @Stephan_Hammer, @SeebeckLab, @barra_lena, @borras & X-less colleagues. https://t.co/1EdomOFj5o
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Happy to see our latest work highlighted in Synfacts. Thank you @thiemechemistry and @ListLaboratory
https://t.co/HJSIaW4W2c
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Another new #cytochromeP450 function! With #enzymes and #directedevolution, and some very clever intuition and analysis, we can push the #chemistry of the biological world into whole new and useful realms. Congrats @Stephan_Hammer and @MarcGBQ .
Enzymes for aerobic arylalkene to ketone oxidation now in @NatureCatalysis. Incl. #directedevolution, detailed mechanistic studies, carbocations, protein dynamics and application in synthesis. Great teamwork with @MarcGBQ
@unibielefeld @IQCCUdG @CeBiTec
https://t.co/8GNt7vsD7X
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Enzymes for aerobic arylalkene to ketone oxidation now in @NatureCatalysis. Incl. #directedevolution, detailed mechanistic studies, carbocations, protein dynamics and application in synthesis. Great teamwork with @MarcGBQ
@unibielefeld @IQCCUdG @CeBiTec
https://t.co/8GNt7vsD7X
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Please to share this collaborative work with the @Stephan_Hammer and @EnzymeNicoCorn. We directly compare a halide methyltransferase (HMT) and a methionine adenosyltransferase (MAT) to access SAM analogues and explore their utility in cascade reactions with methyltransferases.
New Communication out now from @EnzymeNicoCorn, @RentmeisterLab, Stephan C. Hammer & first authors Arne Hoffmann and Kai H. Schülke Now included in 2023 Pioneering Investigators Collection Read here;
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We are hiring a postdoc to work with us on an exciting research project in collaboration with BASF SE. #biocatalysis #proteinengineering 🙏 retweet https://t.co/vpJ8K4yaIY
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