Green Research Group
@GreenGroupMIB
Followers
842
Following
32
Media
7
Statuses
35
Student-run account for the Green group (MIB). Enzyme design. Directed evolution. Genetic code expansion. Industrial biocatalysis.
University of Manchester
Joined May 2020
Congratulations to our group members Anna and Emily for winning presentation and poster prizes respectively, in the biological section of the 2025 UoM Chemistry PGR Conference! 🎉🎉🎉
0
0
11
Very happy to announce that 'Efficient and selective energy transfer photoenzymes powered by visible light' is out today in Nature Chemistry! Congratulations to Rebecca, Ross and everyone else involved in this project! 🎉🎉🎉 https://t.co/mIYqmFCksO
nature.com
Nature Chemistry - Recent studies have shown that energy transfer photoenzymes can be engineered to promote stereocontrolled [2 + 2] cycloadditions; however, existing systems rely on...
0
9
43
Delighted to announce that 'Engineered enzymes for enantioselective nucleophilic aromatic substitutions' is out now in Nature! Congratulations to Tom, George and everyone else involved in this project! 🎉🎉🎉 https://t.co/qnrNLXLhbw
nature.com
Nature - A biocatalytic approach to enantioselective nucleophilic aromatic substitution (SNAr) was achieved through laboratory evolution of highly efficient and selective SNArase biocatalysts.
0
14
70
Exciting PhD opportunity in microfluidics and therapeutic peptide discovery! Join a collaborative team at the University of Manchester for a fully funded PhD in the Obexer, Markin, Hurd and Barran groups. https://t.co/wBUAClqnHt
findaphd.com
PhD Project - Converting acid phosphatases into sulfotransferases that accept inexpensive sulphate donors at The University of Manchester, listed on FindAPhD.com
0
3
4
Applications are now being accepted for Senior Technician (Biomolecular Engineering) and Senior Technician (Bioautomation and high-throughput analytics) roles within the MIB. Please see links below for details and for how to apply. https://t.co/1LDi7a43MM
https://t.co/ikPixFrjiT
jobs.manchester.ac.uk
0
3
2
Very happy to announce that 'Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site' is out now in JACS! A really exciting collaboration with @UWproteindesign 🎉🎉🎉 https://t.co/TdGT9rBTIj
pubs.acs.org
The catalytic versatility of pentacoordinated iron is highlighted by the broad range of natural and engineered activities of heme enzymes such as cytochrome P450s, which position a porphyrin cofactor...
0
13
69
Very happy to the share the news that 'An enzyme cascade enables production of therapeutic oligonucleotides in a single operation' is out now in Science! Great work by @LovelockLab 🎉🎉🎉 https://t.co/bULLQTforv
science.org
A polymerase and endonuclease work in concert to produce high-purity oligonucleotides.
0
6
31
Science meets Christmas! Thanks Emily for the delicious gingerbread lab bench🎄
1
0
5
Very excited to announce our latest paper, 'A Designed Photoenzyme for Enantioselective [2+2]-Cycloadditions', is out now in Nature as an AAP! Congratulations Jonathan, Rebecca and everyone else involved 🎉🎉🎉
1
17
91
The Lovelock group are hiring 3 Postdoctoral Researchers Associates in #biocatalysis and #proteinengineering to join their team at the Manchester Institute of Biotechnology https://t.co/Uh7iag7AsE
0
8
15
Very excited to announce that 'Directed evolution of an efficient and thermostable PET depolymerase' is out now in Nature Catalysis! Congratulations Izzy, Ross and everyone else involved 🎉🎉🎉 https://t.co/nH7URueQ2F
nature.com
Nature Catalysis - Enzymes for poly(ethylene terephthalate) (PET) deconstruction are of interest for plastics recycling, but reports on their directed evolution are missing. Now, an automated,...
1
30
167
Bank holiday reading anyone? Review 'The road to fully programmable protein catalysis' from Baker/Hilvert/Green https://t.co/q7lTH2sJHu
nature.com
Nature - Recent progress in computational enzyme design, active site engineering and directed evolution are reviewed, highlighting methodological innovations needed to deliver improved designer...
0
13
54
Very happy to be sharing this work fresh on the @ChemRxiv this morning from the Green group! ''A Designed Photoenzyme Promotes Enantioselective [2+2]-Cycloadditions via Triplet Energy Transfer'' https://t.co/eIa3pauYhf
2
3
36
Big smiles for Rebecca's graduation day, congratulations! 🍾🍾🍾
0
0
14
Congratulations to the Turner group on their latest paper, 'Multifunctional biocatalyst for conjugate reduction and reductive amination'! Out now in @Nature,
nature.com
Nature - A biocatalytic enzyme originating from bacteria, EneIRED, facilitates amine-activated conjugate alkene reduction followed by reductive amination, efficiently preparing chiral amine...
We are excited to share that our work on a multifunctional enzyme that catalyses conjugate reduction and reductive amination is out now in @nature! This was a collaboration with the Grogan group @YSBL, @Prozomix and @pfizer
https://t.co/8yj5ZGyOzf
1
1
4
Very happy to announce that 'Directed Evolution of an Efficient and Thermostable PET Depolymerase' is now available to read on the ChemRxiv archive, congratulations to Izzy, Ross and everyone else involved! 🎉 https://t.co/qq9FQRxmFO
0
3
20
Massive congratulations to Rebecca, Amy and everyone else involved in 'Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction' 🎉🎉🎉 Out now in Nature Chemistry
3
10
63
We're happy to present our work on the biocatalytic manufacture of Molnupiravir with @GreenGroupMIB and @Prozomix: Gates Foundation funding for University to develop low cost manufacturing route to the promising COVID-19 therapy Molnupiravir
manchester.ac.uk
The University of Manchester has received $500,000 from the Bill & Melinda Gates Foundation to develop a low cost manufacturing route to Molnupiravir, a promising antiviral drug for the treatment of...
4
10
41
Massive congratulations to Rebecca and Ashleigh for passing their PhD vivas this week!!! Can't wait to see where your futures take you 🎉
0
0
10
We are happy to announce that additional experimental data has been added to Ashleigh's paper on the ChemRxiv archive. In particular, a more highly evolved cytidine amino transferase has been developed and the sequence is published here. https://t.co/RzY2cNJ7yn
0
0
9