Sirota Lab at UCSF
@SirotaLab
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Embracing a multitude of computational methods, biomedical data, & unique perspectives to advance precision medicine - & having a lot of fun in the process!
San Francisco, CA
Joined September 2021
Come join us! Info on open postdoc positions below 🧬💻🥳
The @SirotaLab has openings for postdocs who are interested in exploring one or more of the following research areas: electronic health records, multi-omics integration, pregnancy, endometriosis, autoimmune diseases, and Alzheimer’s disease. See below for contact info. Please RT!
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It is with a mix of emotions that I finally announce this work, my very last w/ @atulbutte. Atul believed in the power of open data and our ability to learn from the data we already have to improve healthcare now. This work is a tribute to this belief, made possible by his career
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Tremendous thanks to Martin Papenberg, Cheng Wang, MaĂŻgane Diop, Syed Hassan Bukhari, Boris Oskotsky, Brittany Davidson, Kim Chi Vo, Binya Liu, Juan C. Irwin, Alexis J. Combes, Brice Gaudilliere, Jingjing Li, David K. Stevenson, Gunnar W. Klau, Linda C. Giudice, and Marina Sirota
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Our Anticlust article by Papenberg et al. is now published in Cell Reports Methods, https://t.co/O9McIt6aYy, and featured on their cover, https://t.co/HcirBDK1pc 🎉 @UCSF_BCHSI @HHU_de @UCJointCPH @StanfordMed
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Today, tech & health communities remember life of @atulbutte & celebrate @UCSF_BCHSI 10 years. Colleagues revealed a single person & approach - optimism-generosity-expertise - can shape the future of an industry. His protege @msirota84 of his words to her: Take it, run with it!
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Scientists at Gladstone and @UCSF have identified a combination of two anticancer drugs that the researchers suggest may reverse the changes that occur in the brain during Alzheimer’s disease, potentially slowing or even reversing its symptoms. https://t.co/EXcaTpkonz
genengnews.com
Study harnesses a cell-type-specific, multi-target drug discovery strategy grounded in human data and real-world evidence.
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Using big data to tackle endometriosis! Umair Khan from our lab combined AI and large-scale health records to uncover new insights into a disease that affects millions, out in Cell Reports Medicine today. @SirotaLab @UCSF_BCHSI @CellPressNews
ucsf.edu
Records from millions of patients at University of California health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.
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We are excited to introduce a dedicated Agent Track as part of the SEA-AD DREAM challenge! Informational webinar on Monday 8/11, 3pm PT https://t.co/G2gcn9dAkx Join our worldwide challenge leveraging #snRNAseq data & cutting-edge #AI/#ML approaches. #Alheimers #neuropathology
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Excited to announce the SEA-AD DREAM on @SynapseOrg! Join the global research community to tackle AD using single cell data and innovative AI/ML solutions. Let’s accelerate discovery together! https://t.co/8CIjLs4mmz
@AllenInstitute @DR_E_A_M @Sagebio @SirotaLab @UCSF_BCHSI
synapse.org
'SEA-AD DREAM Challenge - Predicting Alzheimers Pathology from snRNA-seq Data' (Synapse ID: syn66496696) is a project on Synapse. Synapse is a platform for supporting scientific collaborations cen...
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The SEA-AD DREAM Challenge is now live on @SynapseOrg🧠🧑‍💻 Join this worldwide challenge leveraging single-cell data and cutting-edge AI/ML approaches. P.S. An exciting announcement will be coming - stay tuned! #MachineLearning #Alzheimer #OpenScience
https://t.co/gpUvmpZpbN
Excited to announce the SEA-AD DREAM on @SynapseOrg! Join the global research community to tackle AD using single cell data and innovative AI/ML solutions. Let’s accelerate discovery together! https://t.co/8CIjLs4mmz
@AllenInstitute @DR_E_A_M @Sagebio @SirotaLab @UCSF_BCHSI
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How can researchers identify effective drug combinations to treat Alzheimer's disease by targeting different brain cell types simultaneously?@CellCellPress @UCSF_BCHSI "Cell-type-directed network-correcting combination therapy for Alzheimer’s disease" • Alzheimer's disease
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FDA-approved cancer drugs reversed brain changes tied to Alzheimer’s and brought back memory. UCSF and @GladstoneInst researchers combined patient data with genetic analysis to fast-track a potential new treatment. https://t.co/W5onhPHjtV
ucsf.edu
Scientists at UCSF and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its...
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What an honor to be able to be able to share our work on KTVU this morning: https://t.co/zwwdpst29r with my former graduate student Dr. Yaqiao Li! @UCSF_BCHSI @SirotaLab @GladstoneInst
ktvu.com
Researchers from UCSF discovered two FDA-approved cancer drugs appear to slow, or even reverse, memory loss.
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The UCSF community mourns the passing of Atul Butte, MD, PhD, a bold thinker, inspiring mentor and founding director of the Bakar Computational Health Sciences Institute. https://t.co/l0zNMhRdGC
ucsf.edu
Atul Butte, who championed the use of big data in science and health care and inspired a generation of trainees at UC San Francisco and beyond to pursue the fields he pioneered — translational and...
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Now online! Cell-type-directed network-correcting combination therapy for Alzheimer’s disease
cell.com
A multi-cell-type drug discovery strategy targeting dysregulated gene networks in neurons and glia identified letrozole and irinotecan as a combination therapy that significantly improved memory and...
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Do These Two Cancer Drugs Have What It Takes to Beat Alzheimer’s? @UCSF @SirotaLab @GladstoneInst Yadong Huang publish in @CellCellPress !
ucsf.edu
Scientists at UCSF and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its...
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A new study has identified FDA-approved cancer drugs that reverse gene expression signatures associated with Alzheimer’s.
gladstone.org
A new study has identified FDA-approved cancer drugs that reverse the gene expression signatures associated with Alzheimer’s.
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.@msirota84 on how she and colleagues used the EHR, genetics data & @UCSF_BCHSI SPOKE knowledge graph to improve predictive power for #Alzheimer's among women, and detect links with #osteoporosis. For more research highlights, connect to CPH YouTube channel (link in bio)!
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Today, 3/26 at 6-7pm. Join us online for this webinar! AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine
Join the @UCSF @Stanford Enact webinar on Wed., 3/26 w/ BCHSI team "AI, Research, and Future Innovations for Endometriosis and Beyond in the Era of Precision Medicine" @msirota84 @tomiko22 Umair Khan - Details here https://t.co/0ie0nG9lnS
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