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Shozo Ohtsuki Profile
Shozo Ohtsuki

@ShozoOhtsuki

Followers
84
Following
657
Media
4
Statuses
173

Immunology, Protein engineering, Nucleic Acid Drug, Drug Delivery. Research Associate @MayoClinic, Postdoc @StanfordMed, Ph.D. in PharmSci @KyotoU_News

Joined May 2019
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@ShozoOhtsuki
Shozo Ohtsuki
3 years
Our work on immune checkpoint in autoimmune vasculitis, GCA, is out now! Huge thank you to all the amazing collaborators involved from @MdWarrington , @StanfordMed , @MayoClinic & Weyand Lab #GCA #vasculitis https://t.co/NssKmf3Hvl
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cell.com
Ohtsuki et al. report that patients with the autoimmune vasculitis giant cell arteritis (GCA) have a tolerance defect caused by the loss of an inhibitory immune checkpoint. CD155low-expressing...
@MdWarrington
KenWarringtonMD
3 years
🌟 Great work by @ShozoOhtsuki , Dr. Weyand and team 🌟 Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in #GCA #vasculitis @mayoclinic #Rheumtwitter https://t.co/npcCUa4Icc
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@GitaAbhiraman
Gita Abhiraman, MD, PhD
8 months
Excited to share this work from the Garcia Lab out today in @NatureComms! We engineer "cytokine adaptors", molecular switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. https://t.co/CYQzioKFmo
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@i_sturmlechner
Ines Sturmlechner
11 months
I’m very excited to have received a #K99/R00 award from NIA - on my first try! My program focuses on immune aging and T cell dysfunction, in the context of aging and cellular senescence. Send exciting opportunities my way - will go faculty job hunting next year!
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@takahito_myk
Takahito Miyake
1 year
【助教・講師を探しています】 このたび縁がありまして、次年度より、関西学院大学生命環境学部に准教授PIとして着任することになりました。 それに伴い、次年度より私のラボで助教(or 講師)として一緒に研究してくださる方を募集しております。研究で扱う内容は、(次 https://t.co/Gab2sjxXjS
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@SaligramaLab
Saligrama lab_WUSTL
1 year
young adults (<40 years), EBV-specific CD8+ T cells assume preferred differentiation states depending on their peptide specificity. By age >65- years, different T cell specificities had undergone largely distinct aging trajectories
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biorxiv.org
Memory T cells are a highly dynamic and heterogeneous population that is maintained by cytokine-driven homeostatic proliferation interspersed with episodes of antigen-mediated expansion and contrac...
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@biorxiv_immuno
bioRxiv Immunology
1 year
Aging trajectories of memory CD8+ T cells differ by their antigen specificity https://t.co/L4P7dmGtlP #biorxiv_immuno
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@KaymakciMd
Mahmut Kaymakci, MD
1 year
Excited to share our latest article on Subclinical Aortic Inflammation in Patients with PMR in @RheumJnl 🧿 ✅ Persistent aortic inflammation contributes to the development of aortic aneurysms not only in GCA but also in patients with PMR! https://t.co/evCk06ujyO #Vasculitis
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academic.oup.com
AbstractObjectives. To examine the clinicopathologic features of patients with polymyalgia rheumatica (PMR) who had thoracic aorta repair surgery. Findings
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@SaligramaLab
Saligrama lab_WUSTL
1 year
lets try this again -We are searching for #postdocs with deep #expertise in #Tcell #biology #structuralbiology #mutagenesis #invivo #editing #antigen #recognition. Please contact if you are #interested!
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@emeKato
Hideaki E. Kato
1 year
有り難いことにIUPAB (International Union for Pure and Applied Biophysics) から賞を頂けることになりました。 自分達の研究が国際的組織から評価して頂けたというのは素直に嬉しいです。 6/24より始まるIUPAB2024でlectureをすることにもなったので、学会に参加される&お時間のある方はぜひ。
@hekatolab
Hideaki Kato Lab (RCAST, UTokyo)
1 year
加藤英明教授が2024年度のIUPAB Young Investigator Prizeを受賞されました。おめでとうございます! https://t.co/XN9LWBvYEl https://t.co/lLGcXih8t6
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@Abhinav_Jain_19
Abhinav Jain
1 year
I would like to share my wonderful and enjoyable three-year journey in Dr. Jorg Goronzy and Dr. Cornelia Weyand's lab at @MayoClinic. This period has been profoundly enriching, both personally and professionally. In my new journey I am excited joining @UCSF in @diazlaboratory.
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@JCI_insight
JCI insight
2 years
PREX1 improves homeostatic proliferation to maintain a naive CD4+ T cell compartment in older age: https://t.co/UVt7zzjgxH @MayoClinic #Aging #Immunology
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@Abhinav_Jain_19
Abhinav Jain
2 years
I am thrilled to share our first co-author article with Huimin & Hiro from Goronzy Lab PREX1 improves homeostatic proliferation to maintain a naïve CD4 T cell compartment in #older age published in @JCI_insight https://t.co/ktZOBeossX Special shoutout for the whole team 📚🎉
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@KAyasoufi
Katayoun Ayasoufi
2 years
We have an open post-doc position! Our projects include mechanisms of peripheral immune suppression as a result of brain insults. Other projects include responses of tissue resident memory cells in various organs. Check out this job at Duke University:
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@KaoriYamada01
Kaori YAMADA, PhD
2 years
ポスドク1名募集します。アメリカ、シカゴです。J1ビザサポートします。血管内皮細胞の研究を通して、がんの転移や加齢黄斑変性、糖尿病網膜症の治療法を模索しています。 https://t.co/kNMpI8qh9n
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@ns_ore_ns
Nori Saiki
2 years
My co-first author work has been published in Cell Stem Cell! https://t.co/TUnO5EAsFC We modeled episodes of endotheliopathy, thrombosis, and inflammatory responses in COVID-19 by newly developed iPSC-derived human vascular organoid and reconstructed engineered vessels.
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cell.com
COVID-19 can lead to endotheliopathy and multi-organ failure. We developed an infection-permissive human vascular organoid to delineate the key role of complement pathway causing endothelial damage...
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@jsung0906
Jaeyun Sung, PhD
2 years
#ACR2023 @ACRheum is well under way in San Diego! ☀️ Presenting a talk on our giant cell arteritis proteomics research with #MayoClinicRheumatology colleague and friend @MdWarrington at the #Vasculitis session Wed 11/15 11am Room 33A-C. If around, please stop by to say hello 😀👋
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@max_guarda
Max Guarda, MD
2 years
Master and apprentice, side by side at #ACR23! Come check out our posters 0268 and 0269 on CT-guided biopsies for retroperitoneal fibrosis and AKI in VEXAS! #MayoClinic #Rheumatology
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@ACRheum
American College of Rheumatology
2 years
Sunday afternoon at #ACR23: The Klemperer Memorial Lecture will focus on RA as a mitochondrial disease. Preview the session in ACR Convergence Today → https://t.co/MtT5Ae67MF
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@JExpMed
Journal of Experimental Medicine
2 years
Waipan Chan, Ronald Germain et al. @NIAIDNews show that PD-1 engagement by T cells inhibits distinct antigen-evoked signals in a nonlinear manner, strongly influenced by the nature of available TCR ligands. https://t.co/87qnxmZmjt #TumorImmunology #LymphocyteBiology
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@MayoClinic
Mayo Clinic
2 years
For nearly a century, Mayo Clinic physicians have led research advances into the autoimmune disease, giant cell arteritis. Today, they continue to pave the way to help the ~200,000 people affected in the US. Learn more:
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@FrontImmunol
Frontiers - Immunology
2 years
New Research: Use of high-plex data provides novel insights into the temporal artery processes of giant cell arteritis: Objective To identify the key coding genes underlying the biomarkers and pathways associated with giant cell arteritis… #immunology
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