Ekta Shandilya
@ShandilyaEkta
Followers
325
Following
2K
Media
2
Statuses
137
Postdoc @PennStateBME and @psu_chemistry | PhD @IISERMohali
State College, Pennsylvania
Joined September 2019
Happy to share our just published @NatureComms article from @IiserMohali @DCS_IISERMOHALI Thanks to @ANRFIndia for funding. Hard work done by @Rishiram7777 Niranjani @NandhaEttikkan #ReactionDiffusion based system https://t.co/ye3v4cgpDS
nature.com
Nature Communications - Achieving spatiotemporal gating of signals is desirable for mimicking of biological processes, but is challenging to achieve in synthetic systems. Here, the authors report a...
45
21
180
I’ve been building lots of character this year !
8
2
83
We train machine learning models on millions of proteins. But when making predictions, do we need them to understand all proteins at once? Often we need an accurate model for the specific protein we are studying/designing. We address this with ProteinTTT https://t.co/1fj1huDzrZ🧵
5
68
322
The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution. https://t.co/q3AeqGsIS1
31
273
1K
Termites enlist microbes to defend their crops from undesirable fungi.
0
5
27
Huntington’s disease is brutal. A single DNA error → toxic protein → dead brain cells. No cure. Always fatal. Always inherited. But now? Science has flipped the script. How the new gene therapy works: 1️⃣ Huntington’s mutation makes a toxic protein that kills neurons. 2️⃣
155
3K
11K
WIRED just published an article featuring David Liu, cofounder of $PRME and $BEAM. 🧬 This is really something impressive. David Liu’s lab may have just taken prime editing to the next level: a “disease-agnostic” approach, one single therapy could target THOUSANDS of rare
7
36
194
This 1998 paper is, without question, one of the most beautiful in the history of biology. It answers two questions: First, how does a potassium channel let in K+ ions while excluding Na+ ions? And second, how does it funnel 100 million of those ions through each second? These
27
252
1K
Our latest @ChemicalScience ‘Decoding informational entropy of fatty acid and phospholipid vesicle via ordering combinatorial output of hydrazones’ from @DCS_IISERMOHALI @IiserMohali bridging #information theory with #supramolecular systems chemistry https://t.co/cK8gHYcNNy🧵
pubs.rsc.org
Leveraging information entropy to quantitatively measure the organizational diversity and complexity of different chemical systems is a compelling need for next-generation supramolecular and systems...
27
9
100
We are happy to share that our article on chirality-driven non-equilibrium assembly is now published in @angew_chem ! 🎉Congrats to Lenard and Kun for showing how left and right handed aminoacyl phosphates enable control over kinetics and pathways. https://t.co/p91j3M73IC
4
12
116
Fellow motorists, follow the roadmap for an exciting journey! Many thanks to @samuelnanobots and others for their insights, https://t.co/69msfxu3PK
0
6
31
A new and simple model-free method to analyze smFRET experiments. Protein dynamics from nano- to milliseconds without the nasty diffusion decays in standard FCS experiments - kudos to the great Ivan Terterov! Have a look! https://t.co/PU3yXelyWn
2
15
47
New from the Rouhanifard Lab! What if we could sort single cells based on whether a specific gene was actively being transcribed—and then ask what drives that burst? Introducing: NuclampFISH
4
26
123
We just published "NuclampFISH enables cell sorting based on nuclear RNA expression for chromatin analysis" in #BMCGenomics. 📄 Full paper:
1
3
7
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria | Nature
nature.com
Nature - Mitochondria are able to maintain two competing metabolic pathways—oxidative phosphorylation and the reductive synthesis of proline and ornithine—by generating two...
1
37
187
high-throughput single-molecule platform to study DNA supercoiling effect on protein–DNA interactions https://t.co/vD3sDJ9mZY
2
26
124
Getting to the virtual cell is the holy grail of life science. Now there's a challenge on to accelerate it https://t.co/s1qY1eerOb
@arcinstitute @CellCellPress @nvidia @10xGenomics @yusufroohani @StanfordAILab @davey_burke @UltimaGenomics
cell.com
Virtual cells are an emerging frontier at the intersection of artificial intelligence and biology. A key goal of these cell state models is predicting cellular responses to perturbations. The Virtual...
8
71
298
We are excited to publish on our brain ventricle model @PNASNews that can help hydrocephalus research progress further by understanding fluid dynamics in context of shunt implants @hseas
https://t.co/e6NrkzldtS
pnas.org
Hydrocephalus, a neurological condition characterized by an excessive buildup of cerebrospinal fluid (CSF) in the brain, affects millions worldwide...
0
1
12