Sebastian Seung
@SebastianSeung
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@FlyWireNews https://t.co/ZUXm93WUll @eye_wire. Read https://t.co/meh9OZPrQk @WSJ Top 10 Nonfiction 2012. @PrincetonNeuro @PrincetonCS
Princeton, New Jersey
Joined March 2010
A historic milestone for neuroscience! It's been a fantastic journey for the #FlyWire Consortium. This special edition of Nature showcases the power of open science, with nine papers that not only describe the fly connectome, but also make discoveries using it.
Big news! The fly connectome is featured on the cover of a special edition of Nature. This is all possible thanks to the collaboration of 292 members of The FlyWire Consortium! https://t.co/Mrz7Yrx1eU Check out the thread for an overview of the 9 #flywire papers published today
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Another link that isn't paywalled.
nytimes.com
They hoped to make tomorrow’s medicines. Then came Trump.
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Taxpayers: you reap enormous rewards from your modest investment in scientific research. American science is in grave peril. https://t.co/qupotRQSAl
nytimes.com
They hoped to make tomorrow’s medicines. Then came Trump.
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Holy Soma Batman! You never know what you may find when you cruise our MICrONS Explorer, such as a blood vessel piercing the soma of a neuron! 👀 See this incredible find up close using this shortcut: https://t.co/QkoavsnhtS
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Interactive brain-body connectivity at the Codex. Click on thorax, salivary gland, etc, and see the neurons associated with that body part! H/T @mottcallie
https://t.co/5KZxJTVdqx
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FAFB-FlyWire went from brain salami to connectome in 10 years. BANC-FlyWire took 5 years. The next time will be 2x faster still!
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The ongoing commercialization of connectomics by these companies is also a democratization, disseminating cutting-edge technologies and making connectomes accessible to researchers around the world.
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Shout-out to @zettaconnectome for handling tricky locations in the dataset, especially the neck connective running between the brain and cord. And kudos to SixEleven and Aelysia for proofreading and to Yikes for software tools. (I have a financial interest in Zetta.)
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I'll mention just one of the many scientific implications here. Adding the cord to the brain will boost efforts to integrate connectome-based brain simulation with physical simulation of the body.
This preprint is now published at @Nature. With current and former DeepMinders @yuvaltassa, Josh Merel, Matt Botvinick, and my @HHMIJanelia colleagues @vaxenburg, Igor Siwanowicz, @KristinMBranson, @MichaelBReiser, Gwyneth Card and more
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So FlyWire joined forces with the BANC team at @harvardmed, and the current data release is the fruit of our labors. We've proved once again that a connectome can be obtained through cooperation by many small labs. Connectomics is not dominated by large institutions.
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Last year we published the neuronal wiring diagram of a fruit fly brain. This was a huge advance, but something important was missing: the ventral nerve cord (VNC). The VNC is the brain-body interface, analogous to our spinal cord.
Big news! The fly connectome is featured on the cover of a special edition of Nature. This is all possible thanks to the collaboration of 292 members of The FlyWire Consortium! https://t.co/Mrz7Yrx1eU Check out the thread for an overview of the 9 #flywire papers published today
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A wealth of connections, now in the BANC! Congrats to this international consortium for a massive new data release shedding light on brain-body interactions.
Introducing The BANC (Brain and Nerve Cord) connectome preprint! Thanks to all who helped make this synapse-resolution map of an adult fruit fly central nervous system possible! Preprint: https://t.co/aQUyKkIHWD The BANC is publicly available in Codex: https://t.co/dUBuTa4Ilz
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Didn't know this had been quantified: "monozygotic twins differ on average by 5.2 early developmental mutations"
This is not true. Identical twins do not share 100% identical DNA. Close but no dice.
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Neuroglancer was originally developed by @Google for connectomics. It's a fantastic visualization tool for 3D images.
Need an easier way to visualize and collaborate on large-scale volumetric images? Join our live Q&A 'Extending the Neuroglancer Paradigm: Advancing Collaboration on Large-Scale Imaging Data' 👉 Register here: https://t.co/cmewmVMuYs 🗓 Tuesday, July 29th | 12:30pm - 2:00pm ET
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Ancestry of PyTorch explained. I just looked for my old SN2 manual but couldn't find it...
@kchonyc @LeonBottou True story. I used this particular Amiga 1000 to write SN (Léon had his own Amiga) using Emacs and gcc, and to write my PhD thesis with Emacs and LaTeX in 1987. SN, later evolved into SN2 and SN3, and was open sourced under the name Lush in 2001. SN3/Lush (tensor engine with Lisp
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Grant cancellations have been arbitrary, not rational.
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
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Yes the talent pipeline is the only way for the US to succeed in science and tech, because US population is smaller than EU, 4x smaller than China. We win by persuading the best and brightest to come to US. We lose if we drive them away.
@XirtamEsrevni @SebastianSeung @Harvard Give it some time - especially if researchers are not made to feel welcome here they’d soon go elsewhere
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In my US professor vanity, I always assumed Chinese students came to US for its superior universities. My former student informed me that they come to get a high paying US job after graduation.
@SebastianSeung @Harvard Idk, still don't see Europeans & Americans clamoring to go to top Chinese universities. It's always the other way, so something is up.
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Editorial "MAGA’s assault on science is an act of grievous self-harm" "America will pay the price most of all" https://t.co/eUN0NLxsfG From The Economist
economist.com
America will pay the price most of all
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