IBBR's annual pumpkin carving contest did not disappoint! We had everything from Pacman to geese to virtual pumpkins! And the first place winner went to the Pandas! We are so excited to meet Bao Li and Qing Bao @NationalZoo in the new year!

Timescales in Cell Biology

Happy Birthday PDB, announced #OTD in 1971 In Nature New Biology. Today we celebrate the 53rd anniversary of the Protein Data Bank and the PDB depositor community, and congratulate the 2024 Nobel Prize in Chemistry Awardees https://t.co/iK5APvichT

New work on protein design... 🚨S2 immunogen design using advanced simulation @WestpaSoftware WE MD--> opening mechanism--> design--> stabilized protein--> cryoEM structure + immunology @xandra_nuqui @LCasalino88 @McLellan_Lab @ChandranLab https://t.co/Nhm580Tsom

Yesterday a Nobel prize was given for alpha fold. Alpha fold could not exist without the Protein Data Bank (PDB), a public database funded by US taxpayers. Every structural biologist in the world that deposited their structure to the PDB indirectly helped train alpha fold.

These laureates are VERY deserving. But an important addendum—no model could be trained without 40 years of Helen Berman and others’ work at the PDB, and we would not be certain of AF’s success without 30 years of John Moult and others’ work on CASP. Hats off to them as well 🥂

The fabulous Norbert Pardi and I wrote a review about mRNA vaccines for infectious diseases. Maybe worth a read if you are interested in the topic. https://t.co/PaplRna9FS

Happy to share an update to our TCR structure database, TCR3d, now online at @NAR_Open! More structures of TCR complexes, as well as TCR mimic antibodies, pep-MHC complexes, tools, and affinities. @UMD_IBBR @UMDCBMG #tcell https://t.co/hf5XWldEPQ https://t.co/gNuu5Ei7tL

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania @ASBMB @ChemBiochemUMD @Cannabatopia @UMmedschool @PurdueSCBB @GSKUS @skerramilli @MSDBiomarkers Dr Megan Mitchell from @UMD_IBBR and @NIST presents her research on supported bilayers.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania @ASBMB @ChemBiochemUMD @Cannabatopia @UMmedschool Alumni of @PurdueSCBB at the Third Annual Early Career Symposium (@UMD_IBBR). L to R: Patrick Dolan (@LVD_NIAID), Anita Ghosh (@ipiproteins), yours truly, Glenda Soriano (@GSKUS), and @skerramilli (@MSDBiomarkers).

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania @ASBMB @ChemBiochemUMD Joe Kousouros from Dr Jon Fay's lab ( @Cannabatopia ) at @UMmedschool presents his research on #gpcr structural biology.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania @ASBMB Dr Yanxin Liu from @UMD_IBBR and @ChemBiochemUMD.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania Dr Isabel Casas ( @ASBMB ) talks about her professional journey at the Career Session.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania Matt Martin from the Coleman Lab ( @1nsaneNmembrane ) shares his structural work on serotonin transport.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania Juliet Obi from @DeredgeLab shares her #cryoem and #massspec work on #denguefever

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop @ipiproteins @DabillaNathania from @LVD_NIAID talks about her work on #enteroviruses.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @umsop Dr Anita Ghosh from the @ipiproteins gives a talk at the Career Session.

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @timmaitland1 @DeredgeLab @umsop

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci @UMD_IBBR Co-Director Dr John Marino from @NIST and @timmaitland1 from @thermofisher

@SPTLabtech @CWolberger @UMD_IBBR @UMBaltimore @LVD_NIAID @UofMaryland @JohnsHopkins @1nsaneNmembrane @NIST @thermofisher @KempProteins @VWR @GenScript @Proteintech @NikonUSA @KoiralaLab @SmithLabUMBC @DeredgeLab @MiTeGen @BioRadLifeSci Dr Karndeep Singh from @UMBC speaks about his work on #HIV structural biology.