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BökeLab

@LabBoke

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Oocyte Biology and Cellular Dormancy Lab in @CRGenomica, Barcelona, led by Elvan Böke. Joint lab account; tweets by Elvan are signed EB.

Barcelona, Spain
Joined February 2021
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@LabBoke
BökeLab
4 months
Proud to share what we hope will be a reference study on human oocyte proteostasis. Young-donor eggs show globally reduced organelle activity vs. somatic cells, with an even steeper drop as they mature. 👇 for @zaffagg3 's detailed explanation https://t.co/NQ1krrsRYb
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embopress.org
imageimageOocytes are long-lived cells that require specialized adaptations to maintain their fitness. This study shows that human oocytes display low lysosomal, proteasomal, and mitochondrial...
@zaffagg3
Gabriele Zaffagnini
4 months
📣 Paper alert!! Excited to share the 2nd research paper from my time in the @LabBoke at @CRGenomica, out today in the @embojournal! We asked: "how do human oocytes regulate proteostatic organelles under physiological conditions?" We collaborated with @DexeusMujer and employed
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@LabBoke
BökeLab
2 days
It was a pleasure to open the Spanish Society for Reproduction’s @ASEBIRreprod annual congress this morning! #XIIICongresoASEBIR - EB
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@LabBoke
BökeLab
8 days
This is next week! Women biology & health workshop with a mix of experts from medicine and basic sciences - join us if you’re in Barcelona :) - EB
@idibaps
IDIBAPS
4 months
🆕On November 11th, #IDIBAPS is organizing the “Women Biology & Health Workshop” #WBHW A scientific conference to highlight the women's health research♀️ Save the date and sign up👉 https://t.co/QdIcgWoGod
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@LabBoke
BökeLab
18 days
Oh wow - pre-made templates to share :) - EB I’m happy to present my latest research during Plenary II at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 https://t.co/ldXTtPlssQ @ISSCR
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invt.io
Register now
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@LabBoke
BökeLab
28 days
Hypothesis: cava tour and tasting improves team spirit Result: confirmed ✅ Add in games, lunch, and hiking = one unforgettable lab retreat! 🏞️🍾
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@adrianobolondi
Adriano Bolondi, PhD
1 month
🚨JOB ALERT🚨 PLEASE SPREAD and RT We are building a small expert team within the @LabBoke at @CRGenomica @the_prbb to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility. See below 2 calls👇
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@zaffagg3
Gabriele Zaffagnini
2 months
Great to see our work featured in @NatureSMB! Thanks @DimitrisTypas for your coverage! @LabBoke @DexeusMujer
@NatureSMB
NatureStructMolBiol
2 months
New online! A snapshot of proteostasis in human oocytes https://t.co/BiKO1xoANS
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@LabBoke
BökeLab
2 months
Thanks for highlighting our recent work in human oocytes! :) -EB
@NatureSMB
NatureStructMolBiol
2 months
New online! A snapshot of proteostasis in human oocytes https://t.co/BiKO1xoANS
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@LabBoke
BökeLab
3 months
Really looking forward to this workshop! - EB
@Co_Biologists
The Company of Biologists
3 months
Registration is now open for early-career researchers to apply for a funded place at our Workshop on Revisiting Metabolic Fundamentals, organised by @lydfinley& @WilhelmPalm. Find out more and apply at https://t.co/oBmoEsHATn #BiologistsWorkshops
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@zaffagg3
Gabriele Zaffagnini
3 months
Here we go again!! Our paper on #proteostasis in human oocytes featured on the #cover of @embojournal!! A great collaboration with @DexeusMujer @LabBoke! 🥂💪🏻👏🏻
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@hattaca
Hattie Chung
3 months
Our lab at @YaleMed seeks #postdocs with in vivo expertise to pioneer research at the intersection of tissue remodeling & aging. Work with us to uncover immunological & vascular drivers of ovarian aging, applying single-cell, spatial omics, and ML!
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@LabBoke
BökeLab
3 months
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@LabBoke
BökeLab
3 months
We’re so happy that our review on “Proteostasis in cellular dormancy” was chosen for the cover of the August issue of @TrendsBiochem in the old-school way; we were invited! Many thanks to our editor, Sannie Culbertson, and the reviewers for a great experience - EB
@TrendsBiochem
Trends in Biochemical Sciences
3 months
📢 Our August issue is online! 🎨 The cover highlights a Feature Review from Stephanie Rosswag de Souza, @LabBoke and @zaffagg3 on how proteostasis functions in cellular dormancy across a number of examples, from yeast to adult quiescent stem cells and vertebrate oocytes.
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@Newsweek
Newsweek
3 months
"Maintaining the egg's naturally quiet metabolism could be a better idea for preserving quality," said molecular biologist Elvan Böke.
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newsweek.com
"Maintaining the egg's naturally quiet metabolism could be a better idea for preserving quality," said molecular biologist Elvan Böke.
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@LabBoke
BökeLab
4 months
A bittersweet and slightly late! post: we celebrated @AidaRoNu as she heads off to start her own lab in the Department of Physiological Sciences at the University of Barcelona! 🥂 From postdoc to PI, we’re so proud and can’t wait to see all she accomplishes! Go shine, Aida! 🌟🥂
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@zaffagg3
Gabriele Zaffagnini
4 months
📣 Paper alert!! Excited to share the 2nd research paper from my time in the @LabBoke at @CRGenomica, out today in the @embojournal! We asked: "how do human oocytes regulate proteostatic organelles under physiological conditions?" We collaborated with @DexeusMujer and employed
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@reproseminars
Reproseminars
5 months
🧬 We're thrilled to close this semester of Reproseminars with Dr. Elvan Böke (@CRGenomica, Barcelona)! 🗣 Talk (in English): "Evading ageing: metabolic and proteostatic adaptations in oocytes" 🗓 Monday 07/07, Special time! 🕐 1 PM ARG🇦🇷 | 12 PM 🇺🇸 East | 6 PM 🇪🇺 Europe Join us!
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@cjmaddison
Chris J. Maddison
5 months
“Finally, maybe this is controversial but ultimately progress in science is bottlenecked by real-world experiments.” If this is controversial in SF, we’re cooked.
@_jasonwei
Jason Wei
5 months
We don’t have AI self-improves yet, and when we do it will be a game-changer. With more wisdom now compared to the GPT-4 days, it's obvious that it will not be a “fast takeoff”, but rather extremely gradual across many years, probably a decade. The first thing to know is that
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