Roberta Filograna
@RobertaFilogra2
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Joined April 2020
RT @mito_gene: Exciting news from Pretzel Therapeutics! .We’ve launched a Phase 1 trial for our POLG activator—PX578—targeting rare mito. s….
pretzeltx.com
First-in-class approach to targeting mitochondrial DNA polymerase (POLG) with disease modifying potential across mitochondrial DNA depletion syndromes
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RT @WredenbergLab: Interested in mitochondrial biology? We are looking for an enthusiastic PostDoctoral fellow and PhD student to join our….
ki.varbi.com
Do you want to contribute to improving human health? Research at the Division of Molecular Metabolism aims to understand the regulation of mitochondrial function and the role of mitochondrial dysfunct
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🚨PostDoc Alert!.We are looking for an enthusiastic and driven #PostDoc to study the role of mitochondrial dysfunction in neurodegenerative diseases. Join my research group @MolMet_KI within @karolinskainst! #Mitochondria #Neurodegeneration #MitoJobs .
ki.varbi.com
Do you want to contribute to improving human health? Division The Division of Molecular Metabolism aims to understand the regulation of mitochondrial function and the role of mitochondrial dysfunction
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RT @WredenbergLab: We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all coll….
nature.com
Nature Communications - Finding ways to compensate for mitochondrial dysfunction is essential. Here, the authors performed a genome-wide genetic screen to identify genes that mitigate the larvae...
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RT @mitopinionated: New study from us:.High mtDNA copy number promotes lung cancer growth in the mouse, whereas mtD….
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RT @CRC_1218: 🚨Save the date!🚨 Co-organized by our CRC1218 PI, Elisa Motori. EMBO Workshop “Mitochondria in the Nervous System” 🧠⚡ in beaut….
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RT @RubalDiana: 🚨Mitochondrial research out🚨 Our latest work on the synergy between LRPPRC and SLIRP for maintaining mtDNA gene expression….
academic.oup.com
Abstract. In mammals, the leucine-rich pentatricopeptide repeat protein (LRPPRC) and the stem-loop interacting RNA-binding protein (SLIRP) form a complex i
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RT @WredenbergLab: Happy to share our latest manuscript on using quantitative proteomics to diagnose patients with mitochondrial disease. G….
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We are excited to share our lab's first preprint, highlighting the role of the CHCHD2-CHCHD10 complex in preserving tissue homeostasis. A huge thank you to all our collaborators!.
biorxiv.org
The highly conserved CHCHD2 and CHCHD10 are small mitochondrial proteins residing in the intermembrane space. Recently, mutations in the CHCHD2 and CHCHD10 genes have been linked to severe disorders,...
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RT @mitopinionated: New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene….
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Our study is finally out! We here show that PARKIN is dispensable for OXPHOS function in adult mouse tissues and in skeletal muscle from a PD-patient. Thanks to @mitopinionated , @LabMotori, @perlmannlab and Per Svenningsson for the great collaboration!
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RT @hauke_hillen: I have the honor and pleasure of co-organizing the EMBO workshop on Molecular Biology of Mitochondrial Gene Maintenance &….
meetings.embo.org
The mitochondrial genome is essential for cellular energy transduction and cell viability. Mitochondrial DNA (mtDNA) is replicated autonomously, and transcription and translation of mtDNA-encoded pro…
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Just a few days left to apply for a #Postdoc position! Join us in the vibrant work environment at @MolMet_KI in Stockholm!.
PostDoc opportunity!.We are looking for an enthusiastic #PostDoc to study how mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative disease. Join my research group within @MolMet_KI @karolinskainst.
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PostDoc opportunity!.We are looking for an enthusiastic #PostDoc to study how mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative disease. Join my research group within @MolMet_KI @karolinskainst.
ki.varbi.com
Do you want to contribute to improving human health? The research at the Division of Molecular Metabolism aims at understanding the regulation of mitochondrial function and the role of mitochondrial d
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RT @MolMet_KI: Are you interested in understanding the molecular basis of mitochondrial DNA disease? We are looking for enthusiastic PostDo….
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RT @Mito_at_GU: Please see our latest mitochondrial transcription review, together with Ben Tan @mustloveDNA:.
nature.com
Nature Reviews Molecular Cell Biology - A unique feature of mitochondrial DNA function is the coupling of initiation of transcription with that of replication. Tan et al. discuss the choice between...
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RT @metaboflo: Two neighboring cells can be so different! Releasing scDVP - single-cell #DeepVisualProteomics for combined imaging and mass….
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RT @mitopinionated: New preprint from us! Paradoxically, daily treatment of obese mice with inhibitors of mitochondrial transcription (IMT)….
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RT @mitopinionated: The study "PARKIN is not required to sustain OXPHOS function in adult mammalian tissues" by @RobertaFilogra2 et al now….
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RT @tuuliel_lab: Faculty position at Karolinska, in the wonderful Solna campus across the street from us at SciLifeLab.
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