RESOLUTE - Research Empowerment on Solute Carriers
@RESOLUTE_IMI
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The RESOLUTE & REsolution IMI consortia aim at triggering an escalation in the intensity of research on Solute Carriers (SLCs) transporters worldwide.
This work has received support from the EU/EFPIA Innovative Medicines Initiative 2 Joint Undertaking (RESOLUTE grant No 777372).
Joined January 2019
RT @giuliosf: Paper(s) alert from our @RESOLUTE_IMI project – In a compilation of four papers in Molecular Systems Biology we show how we w….
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RT @giuliosf: Are you curious what is known about SLCs? And how they are related? We are enthusiastic to wrap up the series of four (4) man….
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RT @giuliosf: We are thrilled to share the THIRD study of our series which sheds light on the genetic interactions between transporters and….
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RT @giuliosf: Do you want to know with which proteins an SLC membrane transporter socializes? Our @RESOLUTE_IMI series of 4 manuscripts con….
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RT @giuliosf: We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of….
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RT @giuliosf: Finally! It is happening! After 6 years of hard work by formidable teams in 13 institutions @RESOLUTE_IMI, we have ordered an….
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Check out this tour-de-force in technology and assay development by our partners at Novartis, @mpi_mr_hd, and @CeMM_News:
cell.com
Hellweg et al. introduce AspSnFR, a genetically encoded green fluorescent biosensor designed for the real-time measurement of aspartate concentrations in live cells. AspSnFR enables studies of amino...
Online now! AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells by Lars Hellweg, Kai Johnsson, @PLeippe, and colleagues at @EPFL_en @mpi_mr_hd @CeMM_News #chembiol.
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📢Dear followers! It has been an absolute pleasure to share news on Solute Carriers #SLCs transporters with you during the last 5 years! The RESOLUTE @IHIEurope project is ending soon, but all our resources and datasets are available at #CarryTheTorch!.
re-solute.eu
Research Empowerment on Solute Carriers
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RT @madamscientist: Many SLC superfamily #transporters could be included on this schematic, including organellar Na+/H+ exchangers SLC9A9 a….
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RT @MemProtPDB: Structural basis of anticancer drug recognition and amino acid transport by LAT1 | bioRxiv. https:/….
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RT @MemProtPDB: Uncoupled substrate binding underlies the evolutionary switch between Na+ and H+-coupled prokaryotic aspartate transporters….
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RT @DavidBSauer: A massive @RESOLUTE_IMI collaboration with @CmdOxford, #nuvisan, @BiochemOxford, @CeMM_News, @Bayer, @UZH_en . Work of man….
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RT @emeKato: new release1. SpSLC9C1 in lipid nanodiscs. apo.8PCZ: dimer.8PD2,3,5,7: protomer state 1-4. w/ cAMP.8PD8: dimer.8PD9: protomer….
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RT @MemProtPDB: Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP | Nature Comm. .
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RT @MemProtPDB: Mimicking the regulatory state of a major facilitator superfamily sugar transporter | eLife. . #Cry….
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RT @IHanelt: New preprint from the lab and guess what, it is not about a membrane transporter😱: "Sensory kinase KdpD is a tandem serine his….
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RT @MemProtPDB: Cryo-EM structure of TMEM63C suggests it functions as a monomer | Nature Comm. . #CryoEM #MembraneP….
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RT @MemProtPDB: Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport a….
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RT @solutecarriers: Structural investigation of human cystine/glutamate antiporter system xc− (Sxc−) using homology modeling and molecular….
frontiersin.org
The cystine/glutamate antiporter system xc- (Sxc-) belongs to the SLC7 family of plasma membrane transporters. It exports intracellular glutamate along the l...
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RT @MemProtPDB: Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP | eLife . https:….
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