quang-n-nguyen.bsky.social
@QNNDuke
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@NDMOxford DPhil| Erasmus Vaccinology MSc| @DukeU BS| @ArtisVentures Fellow, Computational vaccinology enthusiast š¾ SLO CD8 T cell diversity
Oxford, UK
Joined July 2017
Interested in learning about how some cool follicular T cells modulate B cell and antibody responses in #hooman ? PM me š¤£šš« #vaccinology #immunology #computationalimmunology #bluedevils #follicularTcells
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I am no longer active on social media. Reports of my accounts being hacked have been noted. Please always reach out face-to-face as needed regarding any suspicious message.āŗļø.
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Following suit, I too will no longer be on the dark X -- Plz join me ( catching butterflies on @bluesky.
The chatter is becoming very noisy and I canāt learn as much science here compared to before. Will be off from the blue bird (or the dark X). You can find me on BlueSky
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RT @theHumanBorch: Very cool single-cell visualization package with support for TCR/BCR analysis and compatible with scRepertoire. Blown awā¦.
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RT @simocristea: Brain tumors hijack neural language circuits to fuel their growth š³.
nature.com
Nature - High-grade gliomas functionally remodel neural circuits in the human brain, promoting tumour progression and impairing cognition.
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RT @TsangLab: Really cool paper: refueling T cells by sending mitochondria via a tunnel empowers the T cells to fight tumors better. httā¦.
cell.com
Transfer of mitochondria via nanotubes from bone marrow stem cells to CD8+ TĀ cells augments cellular metabolism, empowering engineered TĀ cells and tumor-infiltrating lymphocytes to counteract...
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FDCs, Tfh/Tfr, and B cells, NK cells, et al. but there is always a place for something else -- a tingible body macrophages that autocorrect will continue to fix into tangible. š
#germinalcenters #follicular #humoral #vaccinology.
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Non-resolving inflammation can induce "bad" lymphoid rxns, leading to dysregulation of host defense & pathogenic autoreactivity. But not in all #autoimmunedisease & cancer patients #Tfh #Tfr #GCreactions .
nature.com
Nature Reviews Immunology - Inflammation can promote the development of lymphoid structures in tissue sites at which they do not normally occur. Here, the authors discuss how these ectopic...
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RT @TsangLab: Excited to share our new paper on temporal analysis of vaccine+/- adjuvant hours to 100 days (14 time pts). Vax alone inducesā¦.
cell.com
Apps etĀ al. use systems immunology to assess H5N1 vaccination with and without the AS03 adjuvant, revealing dynamic response patterns associated with the adjuvant and vaccine immunogenicity. Indepe...
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Adaptive and innate immune cell diversity and composition underlying #immunevariations between human populations, and how they are influenced by both host genetics and non-genetic factors. Quite an insightful read on #systemsimmunology w historical touch.
cell.com
The genetic architecture of the human immune response has been shaped by varying selective pressures and population admixture, making population genetic data a powerful tool to derive greater...
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RT @LukasValihrach: Mapping cellular interactions from spatially resolved transcriptomics dataš
nature.com
Nature Methods - Spacia is a multiple-instance learning model for cellācell communication (CCC) interference in single-cell resolution spatially resolved transcriptomics data. Spacia can map...
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"Several HLA haplotypes, some of which encode ligands for natural killer cell receptors (KIRs), were acquired through admixture with Denisovans or Neanderthals." š #introgression
cell.com
The genetic architecture of the human immune response has been shaped by varying selective pressures and population admixture, making population genetic data a powerful tool to derive greater...
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RT @erturklab: What if we could map every cell in the body, revealing its location and molecular identity? In this @NatureMethods perspectiā¦.
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RT @LukasValihrach: Directly selecting cell-type marker genes for single-cell clustering analyses.
cell.com
Chen etĀ al. develop Festem (feature selection by expectation maximization test), a method that enables direct cell-type marker gene selection for downstream clustering of scRNA-seq data. Festem...
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RT @clintomics: Single cell profiling is costly and not yet scalable across large population cohorts. Here an interesting āsemi-profilingāā¦.
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RT @mjwsim: Love Immunology? Hate Cancer?. Come join the Centre for Immuno-Oncology as a senior postdoc in Immunopeptidomics. https://t.cā¦.
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RT @CalvinYLaw_: Extremely proud and excited to share my thesis work from the Choi lab @jaehyukchoimd, in collaboration with @Deepakarao anā¦.
nature.com
Nature - Insufficient AHR activation has been suggested in SLE, and augmenting AHR activation therapeutically may prevent CXCL13+ TPH/TFH differentiation and the subsequent recruitment of B cells...
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RT @NimaAghaeepour: Stanford Medicine is making a large investment to hire multiple faculty in AI/ML. I'm one of the co-chairs. If you haveā¦.
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RT @d_brueckner: š¢Hot off the press: our review on "tissue active matter". Together with @EdouardHannezo, we review theoretical approachesā¦.
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RT @simocristea: R package to query the Human Cell Atlas at the tissue, condition or sample level.
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