Princeton Neuroscience Institute
@PrincetonNeuro
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Discoveries and developments from the @Princeton Neuroscience Institute.
Princeton, NJ
Joined May 2013
🧠 When faced with the same evidence, people can arrive at different outcomes, especially when the decision is difficult. For instance, two different drivers in rush hour traffic see the same congested road, yet one might speed up to merge while another cautiously brakes. How
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Pleased to share a preprint with grad student Steven Mesquiti! Steven reviews recent uses of AI in mental health research and treatment. Provides an accessible entrypoint to the topic, covers lots of applications, and identifies *super* important concerns:
osf.io
Mental health challenges add immensely to the global burden of disease, yet traditional approaches to psychological assessment and care remain resource-intensive and often inaccessible. There is...
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Sven's story is one that almost wasn't (aspiring physicist-turned-neuroscientist) -- learn how he wound up studying the complex connections between neurons. 📰: https://t.co/sQPSEoixpq
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Jessie's story starts in the suburbs of Montreal, where she was inspired to ask big questions from her uncle at age 6. Now, Muir pinpoints specific neurons involved in depression that are responsive to psychedelics. 📰: https://t.co/tjpEf2wVwz
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Congrats to PNI postdoc Jessie Muir of the @tinakim_neuro lab and @Princeton neuroscience PhD alumnus @sdorkenw *23 (of the @MurthyLab + @SebastianSeung lab) on being recognized as two of @statnews's 2025 Wunderkinds! 📰: https://t.co/plV2rpa4DP
#STATWunderkinds
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This morning Larry Abbott, 2024 Brain Prize winner, delivered a plenary lecture at #ECNP2025. It was a stunning example of how reconstruction of neural circuits at synapse resolution can provide fundamental insights into mechanisms of circuit computation. #NeuralCircuits
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Over a year ago, the surprising complex brain of the humble fruit fly was mapped after a decade of work. 🪰✅ The ~300 person team was led by @princeton and incl. #ElectronMicroscopy experts from @AllenInstitute. 🔗 https://t.co/jRhxLpK1z2 Video: @quorumetrix @flywirenews
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The Chris Chang Group publishes fascinating research in Molecular Cell identifying the role of copper in the evolution of sleep. Great work Tong, Aidan, Kelly, Chris et al. Enjoy our story latest on their work here: https://t.co/nnvhe35cMB
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I had the pleasure of writing a profile of a scientist I greatly admired and whose work continues to inspire me: Dale Purves ( https://t.co/dJOTLmxjaM):
https://t.co/gO4IghMsYk
aeon.co
How can you have a picture of the world when your brain is locked up in your skull? Neuroscientist Dale Purves has clues
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One year after @FlyWireNews — led by @PrincetonNeuro's Mala Murthy and @SebastianSeung — published the first-ever complete connectome of an adult fruit fly brain, scientists around the world are using its data to make their own discoveries.
thetransmitter.org
Nine Drosophila researchers share how the connectome transformed the field and what additional new tools they would like to see.
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Congrats🥂 to Callan O’Shea, a MolBio M.D./Ph.D student and newest recipient of the New Jersey Alliance for Clinical and Translational Science Award (NJ ACTS) T32 Fellowship. O'Shea is advised by associated faculty member Sam Wang. https://t.co/WXcpgnyhtW
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To celebrate the first anniversary of the release of FlyWire, we asked nine neuroscientists to share how they are using connectome data in their research and what they hope is in store for the future of fly connectomics. By @FrankieRivera25
https://t.co/fELW4sGif4
thetransmitter.org
Nine Drosophila researchers share how the connectome transformed the field and what additional new tools they would like to see.
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The 2025 Nobel Prize in Physiology or Medicine was awarded today to Princeton MolBio graduate alumna Mary Brunkow *91 “for groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.” https://t.co/spTMD0OzB9
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Congrats to @tinakim_neuro of ODBI and @PrincetonNeuro on being selected as a Freeman Hrabowski Scholar by @HHMINEWS! 🧵
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We're hiring! The @Princeton Neuroscience Institute and Department of Psychology (@PsychPrinceton) invite applications for a joint hire Assistant Professor in human cognitive neuroscience 🧠 Review of applications begin Oct 15. More details here: https://t.co/mrRAZBt73J
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⏰ Deadline approaching — apply for the PNI C.V. Starr Fellowship by Oct 10! 🧠 Up to 3 years of salary and research support, along with world-class faculty mentorship and facilities. 🔗 Learn more: https://t.co/ChebsItRl3
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With the help of AI, @Princeton’s @brody_lab can now pinpoint the exact moment a rat makes up its mind — just by reading its brain activity 🧠🐀 📰: https://t.co/ijJQYtKPfK
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Scientists can now freeze-frame the exact moment an animal makes up their mind and commits to a choice — simply by looking at their brain activity. In a new study from @PrincetonNeuro, researchers used AI to trace the trajectory of decision making in the frontal cortex of rats,
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Looking for a neuroscience postdoc opportunity with competitive salary + research funds? Apply for PNI's C.V. Starr Fellowship, which offers collaboration, mentorship, and up to 3 years of support! Applications due Oct 10. Learn more 🔗 https://t.co/ChebsIupaB
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🛑 Attention researchers who train freely-moving rodents! Jess Breda and I developed a protocol for training center-port nose fixation 61% faster than a previous curriculum while keeping violation rates low. Preprint here:
biorxiv.org
Center-port fixation is a common prerequisite for many freely-moving rodent tasks in neuroscience and psychology. However, typical protocols for shaping this behavior are non-standardized and...
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